| MmpL3 as a target for the treatment of drug-resistant nontuberculous mycobacterial infections W Li, A Yazidi, AN Pandya, P Hegde, W Tong, ... Frontiers in microbiology 9, 1547, 2018 | 54 | 2018 |
| Indole-2-Carboxamides Are Active against Mycobacterium abscessus in a Mouse Model of Acute Infection AN Pandya, PK Prathipati, P Hegde, W Li, KF Graham, S Mandal, ... Antimicrobial agents and chemotherapy 63 (3), 10.1128/aac. 02245-18, 2019 | 40 | 2019 |
| Antitubercular agents CC Aldrich, RS Wallis, RP Remmel, P Hegde, CL Stallings Burger's Medicinal Chemistry and Drug Discovery, 1-110, 2003 | 18 | 2003 |
| Proton transfer activity of the reconstituted Mycobacterium tuberculosis MmpL3 is modulated by substrate mimics and inhibitors Casey Stevens, Svilana Babii, Amitkumar N Pandya, Wei Li, Yupeng Li ... PNAS 119 (30), e2113963119, 2022 | 17* | 2022 |
| Mycobacterium tuberculosis PanD Structure–Function Analysis and Identification of a Potent Pyrazinoic Acid-Derived Enzyme Inhibitor P Ragunathan, M Cole, C Latka, WW Aragaw, P Hegde, J Shin, ... ACS chemical biology 16 (6), 1030-1039, 2021 | 16 | 2021 |
| Redesign of Rifamycin Antibiotics to Overcome ADP‐Ribosylation‐Mediated Resistance T Lan, US Ganapathy, S Sharma, YM Ahn, M Zimmerman, V Molodtsov, ... Angewandte Chemie 134 (45), e202211498, 2022 | 14 | 2022 |
| Formulation and characterization of ternary amorphous solid dispersions of a highly potent anti-tubercular agent and curcumin S Borde, P Hegde, P Prathipati, J North, D Kumari, H Chauhan Journal of Drug Delivery Science and Technology 64, 102564, 2021 | 12 | 2021 |
| 8-cyanobenzothiazinone analogs with potent antitubercular activity G Zhang, L Sheng, P Hegde, Y Li, CC Aldrich Medicinal Chemistry Research 30, 449-458, 2021 | 12 | 2021 |
| Reinvestigation of the structure-activity relationships of isoniazid P Hegde, HIM Boshoff, Y Rusman, WW Aragaw, CE Salomon, T Dick, ... Tuberculosis 129, 102100, 2021 | 11 | 2021 |
| Structural determinants of indole-2-carboxamides: identification of lead acetamides with pan antimycobacterial activity P Bhattarai, P Hegde, W Li, PK Prathipati, CM Stevens, L Yang, H Zhou, ... Journal of medicinal chemistry 66 (1), 170-187, 2022 | 10 | 2022 |
| β-lactamase-mediated fragmentation: historical perspectives and recent advances in diagnostics, imaging, and antibacterial design MS Cole, PV Hegde, CC Aldrich ACS Infectious Diseases 8 (10), 1992-2018, 2022 | 9 | 2022 |
| Innovative Strategies for the Construction of Diverse 1′-Modified C-Nucleoside Derivatives S Panda, TN Poudel, P Hegde, CC Aldrich The Journal of Organic Chemistry 86 (23), 16625-16640, 2021 | 8 | 2021 |
| Identification of 5-(Aryl/Heteroaryl) amino-4-quinolones as potent membrane-disrupting agents to combat antibiotic-resistant Gram-positive bacteria JR Schultz, SK Costa, GR Jachak, P Hegde, M Zimmerman, Y Pan, ... Journal of medicinal chemistry 65 (20), 13910-13934, 2022 | 7 | 2022 |
| Structural and Mechanistic Insights into Mycobacterium abscessus Aspartate Decarboxylase PanD and a Pyrazinoic Acid-Derived Inhibitor WG Saw, CY Leow, A Harikishore, J Shin, MS Cole, WW Aragaw, ... ACS infectious diseases 8 (7), 1324-1335, 2022 | 7 | 2022 |
| Synthesis and biological evaluation of orally active prodrugs and analogs of para-aminosalicylic acid (PAS) PV Hegde, MD Howe, MD Zimmerman, HIM Boshoff, S Sharma, ... European journal of medicinal chemistry 232, 114201, 2022 | 7 | 2022 |
| Structure activity relationship of pyrazinoic acid analogs as potential antimycobacterial agents PV Hegde, WW Aragaw, MS Cole, G Jachak, P Ragunathan, S Sharma, ... Bioorganic & medicinal chemistry 74, 117046, 2022 | 5 | 2022 |
| Polyfluorinated salicylic acid analogs do not interfere with siderophore biosynthesis P Hegde, MO Orimoloye, S Sharma, CA Engelhart, D Schnappinger, ... Tuberculosis 140, 102346, 2023 | 3 | 2023 |
| Drugging the microbiome: targeting small microbiome molecules S Sharma, P Hegde, S Panda, MO Orimoloye, CC Aldrich Current Opinion in Microbiology 71, 102234, 2023 | 3 | 2023 |
| 1′-Cyano intermediate enables rapid and stereoretentive access to 1′-modified Remdesivir nucleosides TN Poudel, S Panda, M Orimoloye, P Hegde, CC Aldrich The Journal of Organic Chemistry 87 (21), 14452-14462, 2022 | 3 | 2022 |
| Chemoselective reduction of tertiary amides by 1,3-diphenyldisiloxane (DPDS) CA Travis Hammerstad, Pooja V Hegde, Kathleen J Wang Synthesis, 2021 | 3* | 2021 |
