Exposure of bovine oocytes and embryos to elevated non-esterified fatty acid concentrations: integration of epigenetic and transcriptomic signatures in resultant blastocysts KLJ Desmet, V Van Hoeck, D Gagné, E Fournier, A Thakur, AM O’doherty, ... BMC genomics 17, 1-18, 2016 | 111 | 2016 |
S1P stimulates proliferation by upregulating CTGF expression through S1PR2-mediated YAP activation JC Cheng, EY Wang, Y Yi, A Thakur, SH Tsai, PA Hoodless Molecular Cancer Research 16 (10), 1543-1555, 2018 | 68 | 2018 |
Hepatocyte nuclear factor 4‐alpha is essential for the active epigenetic state at enhancers in mouse liver A Thakur, JCH Wong, EY Wang, J Lotto, D Kim, JC Cheng, M Mingay, ... Hepatology 70 (4), 1360-1376, 2019 | 65 | 2019 |
TGF-β1 induces VEGF expression in human granulosa-lutein cells: a potential mechanism for the pathogenesis of ovarian hyperstimulation syndrome L Fang, Y Li, S Wang, Y Li, HM Chang, Y Yi, Y Yan, A Thakur, PCK Leung, ... Experimental & molecular medicine 52 (3), 450-460, 2020 | 46 | 2020 |
5-Hydroxymethylation marks a class of neuronal gene regulated by intragenic methylcytosine levels RE Irwin, A Thakur, KM O'Neill, CP Walsh Genomics 104 (5), 383-392, 2014 | 35 | 2014 |
Ontogeny, conservation and functional significance of maternally inherited DNA methylation at two classes of non-imprinted genes CE Rutledge, A Thakur, KM O’Neill, RE Irwin, S Sato, K Hata, CP Walsh Development 141 (6), 1313-1323, 2014 | 29 | 2014 |
G protein-coupled estrogen receptor stimulates human trophoblast cell invasion via YAP-mediated ANGPTL4 expression JC Cheng, L Fang, Y Li, A Thakur, PA Hoodless, Y Guo, Z Wang, Z Wu, ... Communications biology 4 (1), 1285, 2021 | 27 | 2021 |
DNA methylation plays an important role in promoter choice and protein production at the mouse Dnmt3L locus AM O'Doherty, CE Rutledge, S Sato, A Thakur, DJ Lees-Murdock, K Hata, ... Developmental biology 356 (2), 411-420, 2011 | 27 | 2011 |
YAP transcriptionally regulates ErbB2 to promote liver cell proliferation EY Wang, JC Cheng, A Thakur, Y Yi, SH Tsai, PA Hoodless Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1861 (9), 854-863, 2018 | 25 | 2018 |
Depletion of DNMT1 in differentiated human cells highlights key classes of sensitive genes and an interplay with polycomb repression KM O’Neill, RE Irwin, SJ Mackin, SJ Thursby, A Thakur, C Bertens, ... Epigenetics & chromatin 11, 1-21, 2018 | 24 | 2018 |
Tumor-associated antigen PRAME exhibits dualistic functions that are targetable in diffuse large B cell lymphoma K Takata, LC Chong, D Ennishi, T Aoki, MY Li, A Thakur, S Healy, ... The Journal of Clinical Investigation 132 (10), 2022 | 23 | 2022 |
Association of circulating monocyte chemoattractant protein‐1 levels with polycystic ovary syndrome: A meta‐analysis Z Wu, L Fang, Y Li, Y Yan, A Thakur, JC Cheng, YP Sun American Journal of Reproductive Immunology 86 (2), e13407, 2021 | 23 | 2021 |
SOX9 reprograms endothelial cells by altering the chromatin landscape BM Fuglerud, S Drissler, J Lotto, TL Stephan, A Thakur, R Cullum, ... Nucleic acids research 50 (15), 8547-8565, 2022 | 22 | 2022 |
Widespread recovery of methylation at gametic imprints in hypomethylated mouse stem cells following rescue with DNMT3A2 A Thakur, SJ Mackin, RE Irwin, KM O’Neill, G Pollin, C Walsh Epigenetics & Chromatin 9, 1-15, 2016 | 10 | 2016 |
Imprint stability and plasticity during development SJ Mackin, A Thakur, CP Walsh Reproduction 156 (2), R43-R55, 2018 | 8 | 2018 |
Cell diversity and plasticity during atrioventricular heart valve EMTs J Lotto, R Cullum, S Drissler, M Arostegui, VC Garside, BM Fuglerud, ... Nature Communications 14 (1), 5567, 2023 | 4 | 2023 |
The UHRF1 protein is a key regulator of retrotransposable elements and innate immune response to viral RNA in human cells RE Irwin, C Scullion, SJ Thursby, M Sun, A Thakur, L Hilman, B Callaghan, ... Epigenetics 18 (1), 2216005, 2023 | 3 | 2023 |
HNF4A guides the MLL4 complex to establish and maintain H3K4me1 at gene regulatory elements A Thakur, K Park, R Cullum, BM Fuglerud, M Khoshnoodi, S Drissler, ... Communications Biology 7 (1), 144, 2024 | 2 | 2024 |
Single-cell transcriptomics reveals diversity during heart valve epithelial-to-mesenchymal transitions J Lotto, R Cullum, S Drissler, M Arostegui, V Garside, B Fuglerud, ... | 2 | 2022 |
SOX9 acts as a dynamic pioneer factor inducing stable changes in the chromatin landscape to reprogram endothelial cells BM Fuglerud, S Drissler, J Lotto, TL Stephan, A Thakur, R Cullum, ... bioRxiv, 2020.09. 11.293993, 2020 | 2 | 2020 |