Safety and efficacy of rituximab in systemic sclerosis (DESIRES): a double-blind, investigator-initiated, randomised, placebo-controlled trial S Ebata, A Yoshizaki, K Oba, K Kashiwabara, K Ueda, Y Uemura, ... The Lancet Rheumatology 3 (7), e489-e497, 2021 | 150 | 2021 |
Contribution of soluble forms of programmed death 1 and programmed death ligand 2 to disease severity and progression in systemic sclerosis T Fukasawa, A Yoshizaki, S Ebata, K Nakamura, R Saigusa, S Miura, ... Arthritis & Rheumatology 69 (9), 1879-1890, 2017 | 67 | 2017 |
Rituximab therapy is more effective than cyclophosphamide therapy for Japanese patients with anti‐topoisomerase I‐positive systemic sclerosis‐associated interstitial lung disease S Ebata, A Yoshizaki, T Fukasawa, S Miura, T Takahashi, H Sumida, ... The Journal of Dermatology 46 (11), 1006-1013, 2019 | 59 | 2019 |
Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis A Kuzumi, A Yoshizaki, KM Matsuda, H Kotani, Y Norimatsu, M Fukayama, ... Nature communications 12 (1), 5947, 2021 | 49 | 2021 |
Skin thickness score as a surrogate marker of organ involvements in systemic sclerosis: a retrospective observational study KM Matsuda, A Yoshizaki, A Kuzumi, T Fukasawa, S Ebata, S Miura, ... Arthritis research & therapy 21, 1-10, 2019 | 39 | 2019 |
Single-cell-level protein analysis revealing the roles of autoantigen-reactive B lymphocytes in autoimmune disease and the murine model T Fukasawa, A Yoshizaki, S Ebata, A Yoshizaki-Ogawa, Y Asano, ... Elife 10, e67209, 2021 | 37 | 2021 |
Combined immunosuppressive therapy provides favorable prognosis and increased risk of cytomegalovirus reactivation in anti‐melanoma differentiation‐associated gene 5 antibody … KM Matsuda, A Yoshizaki, A Kuzumi, T Fukasawa, S Ebata, ... The Journal of Dermatology 47 (5), 483-489, 2020 | 33 | 2020 |
B cell depletion inhibits fibrosis via suppression of profibrotic macrophage differentiation in a mouse model of systemic sclerosis H Numajiri, A Kuzumi, T Fukasawa, S Ebata, A Yoshizaki‐Ogawa, ... Arthritis & Rheumatology 73 (11), 2086-2095, 2021 | 26 | 2021 |
Interleukin-17 pathway inhibition with brodalumab in early systemic sclerosis: Analysis of a single-arm, open-label, phase 1 trial T Fukasawa, A Yoshizaki, S Ebata, M Fukayama, A Kuzumi, Y Norimatsu, ... Journal of the American Academy of Dermatology 89 (2), 366-369, 2023 | 24 | 2023 |
Safety and efficacy of rituximab in systemic sclerosis (DESIRES): open-label extension of a double-blind, investigators-initiated, randomised, placebo-controlled trial S Ebata, A Yoshizaki, K Oba, K Kashiwabara, K Ueda, Y Uemura, ... The Lancet Rheumatology 4 (8), e546-e555, 2022 | 24 | 2022 |
New era in systemic sclerosis treatment: recently approved therapeutics S Ebata, A Yoshizaki-Ogawa, S Sato, A Yoshizaki Journal of Clinical Medicine 11 (15), 4631, 2022 | 22 | 2022 |
Serum interleukin‐34 levels in patients with systemic sclerosis: Clinical association with interstitial lung disease A Kuzumi, A Yoshizaki, S Toyama, T Fukasawa, S Ebata, K Nakamura, ... The Journal of dermatology 45 (10), 1216-1220, 2018 | 22 | 2018 |
Predictors of rituximab effect on modified Rodnan skin score in systemic sclerosis: a machine-learning analysis of the DesiReS trial S Ebata, K Oba, K Kashiwabara, K Ueda, Y Uemura, T Watadani, ... Rheumatology 61 (11), 4364-4373, 2022 | 21 | 2022 |
Nucleosome in patients with systemic sclerosis: possible association with immunological abnormalities via abnormal activation of T and B cells A Yoshizaki, T Taniguchi, R Saigusa, T Fukasawa, S Ebata, H Numajiri, ... Annals of the Rheumatic Diseases 75 (10), 1858-1865, 2016 | 20 | 2016 |
Interleukin (IL)‐17F and IL‐17E are related to fibrosis and vasculopathy in systemic sclerosis M Fukayama, A Yoshizaki, T Fukasawa, S Ebata, A Kuzumi, ... The Journal of Dermatology 47 (11), 1287-1292, 2020 | 14 | 2020 |
Involvement of B cells in the development of systemic sclerosis A Yoshizaki, T Fukasawa, S Ebata, A Yoshizaki-Ogawa, S Sato Frontiers in Immunology 13, 938785, 2022 | 12 | 2022 |
Autoantibody landscape revealed by wet protein array: sum of autoantibody levels reflects disease status KM Matsuda, A Yoshizaki, K Yamaguchi, E Fukuda, T Okumura, K Ogawa, ... Frontiers in Immunology 13, 893086, 2022 | 12 | 2022 |
Rapid alteration of serum interleukin‐6 levels may predict the reactivity of iv cyclophosphamide pulse therapy in systemic sclerosis‐associated interstitial lung disease H Numajiri, A Yoshizaki, T Fukasawa, S Ebata, K Nakamura, T Yamashita, ... The Journal of Dermatology 45 (10), 1221-1224, 2018 | 12 | 2018 |
Long-term outcomes after rituximab treatment for patients with systemic sclerosis: follow-up of the DESIRES trial with a focus on serum immunoglobulin levels A Kuzumi, S Ebata, T Fukasawa, KM Matsuda, H Kotani, ... JAMA dermatology 159 (4), 374-383, 2023 | 11 | 2023 |
Unprecedented success of rituximab therapy for prednisolone-and immunosuppressant-resistant systemic sclerosis-associated interstitial lung disease S Ebata, A Yoshizaki, T Fukasawa, K Nakamura, T Yamashita, S Miura, ... Scandinavian Journal of Rheumatology 46 (3), 247-252, 2017 | 10 | 2017 |