The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase! SA Wickström, A Lange, E Montanez, R Fässler The EMBO journal 29 (2), 281-291, 2010 | 315 | 2010 |
Comprehensive single cell mRNA profiling reveals a detailed roadmap for pancreatic endocrinogenesis A Bastidas-Ponce, S Tritschler, L Dony, K Scheibner, M Tarquis-Medina, ... Development 146 (12), dev173849, 2019 | 199 | 2019 |
Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae SA Wickström, A Lange, MW Hess, J Polleux, JP Spatz, M Krüger, ... Developmental cell 19 (4), 574-588, 2010 | 197 | 2010 |
Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment M Kim, M Ogawa, Y Fujita, Y Yoshikawa, T Nagai, T Koyama, S Nagai, ... Nature 459 (7246), 578-582, 2009 | 196 | 2009 |
Integrin-linked kinase is an adaptor with essential functions during mouse development A Lange, SA Wickström, M Jakobson, R Zent, K Sainio, R Fässler Nature 461 (7266), 1002-1006, 2009 | 159 | 2009 |
Targeted pharmacological therapy restores β-cell function for diabetes remission S Sachs, A Bastidas-Ponce, S Tritschler, M Bakhti, A Böttcher, ... Nature Metabolism 2 (2), 192-209, 2020 | 118 | 2020 |
Systematic single-cell analysis provides new insights into heterogeneity and plasticity of the pancreas S Tritschler, FJ Theis, H Lickert, A Böttcher Molecular Metabolism 6 (9), 974-990, 2017 | 117 | 2017 |
Modelling the endocrine pancreas in health and disease M Bakhti, A Böttcher, H Lickert Nature Reviews Endocrinology 15 (3), 155-171, 2019 | 108 | 2019 |
The late endosomal p14–MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration N Schiefermeier, JM Scheffler, MEG de Araujo, T Stasyk, T Yordanov, ... The Journal of cell biology 205 (4), 525, 2014 | 97 | 2014 |
Point mutations in the PDX1 transactivation domain impair human β-cell development and function X Wang, M Sterr, I Burtscher, A Böttcher, J Beckenbauer, J Siehler, ... Molecular metabolism 24, 80-97, 2019 | 76 | 2019 |
Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice A Aliluev, S Tritschler, M Sterr, L Oppenländer, J Hinterdobler, T Greisle, ... Nature metabolism 3 (9), 1202-1216, 2021 | 73 | 2021 |
Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates A Böttcher, M Büttner, S Tritschler, M Sterr, A Aliluev, L Oppenländer, ... Nature cell biology 23 (1), 23-31, 2021 | 66 | 2021 |
How ILK and kindlins cooperate to orchestrate integrin signaling RT Böttcher, A Lange, R Fässler Current opinion in cell biology 21 (5), 670-675, 2009 | 62 | 2009 |
Epithelial cell plasticity drives endoderm formation during gastrulation K Scheibner, S Schirge, I Burtscher, M Büttner, M Sterr, D Yang, ... Nature cell biology 23 (7), 692-703, 2021 | 56 | 2021 |
Flattop regulates basal body docking and positioning in mono-and multiciliated cells M Gegg, A Böttcher, I Burtscher, S Hasenoeder, C Van Campenhout, ... Elife 3, e03842, 2014 | 52 | 2014 |
Integrin-linked kinase regulates p38 MAPK-dependent cell cycle arrest in ureteric bud development J Smeeton, X Zhang, N Bulus, G Mernaugh, A Lange, CM Karner, ... Development 137 (19), 3233-3243, 2010 | 51 | 2010 |
Activation of the c‐Met receptor complex in fibroblasts drives invasive cell behavior by signaling through transcription factor STAT3 A Cramer, S Kleiner, M Westermann, A Meissner, A Lange, K Friedrich Journal of Cellular Biochemistry 95 (4), 805-816, 2005 | 48 | 2005 |
scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies KT Schmid, B Höllbacher, C Cruceanu, A Böttcher, H Lickert, EB Binder, ... Nature communications 12 (1), 6625, 2021 | 45 | 2021 |
Local call: from integrins to actin assembly S Wiesner, A Lange, R Fässler Trends in cell biology 16 (7), 327-329, 2006 | 38 | 2006 |
CD81 marks immature and dedifferentiated pancreatic β-cells C Salinno, M Büttner, P Cota, S Tritschler, M Tarquis-Medina, ... Molecular Metabolism 49, 101188, 2021 | 37 | 2021 |