Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation RA Ward, C Brassington, AL Breeze, A Caputo, S Critchlow, G Davies, ... Journal of medicinal chemistry 55 (7), 3285-3306, 2012 | 187 | 2012 |
Acoustic mist ionization platform for direct and contactless ultrahigh-throughput mass spectrometry analysis of liquid samples I Sinclair, M Bachman, D Addison, M Rohman, DC Murray, G Davies, ... Analytical chemistry 91 (6), 3790-3794, 2019 | 118 | 2019 |
Novel acoustic loading of a mass spectrometer: toward next-generation high-throughput MS screening I Sinclair, R Stearns, S Pringle, J Wingfield, S Datwani, E Hall, L Ghislain, ... Journal of Laboratory Automation 21 (1), 19-26, 2016 | 114 | 2016 |
Structure-based design of potent and selective inhibitors of the metabolic kinase PFKFB3 S Boyd, JL Brookfield, SE Critchlow, IA Cumming, NJ Curtis, J Debreczeni, ... Journal of medicinal chemistry 58 (8), 3611-3625, 2015 | 97 | 2015 |
Nanopartiicles and intracellular applications of surface-enhanced Raman spectroscopy jack taylor, anna heufner, L Li, jonathan wingfield, sumeet mahajan Analyst 141, 5037-5055, 2016 | 95 | 2016 |
Oxygen affinities of metronidazole-resistant and-sensitive stocks of Giardia intestinalis JE Ellis, JM Wingfield, D Cole, PFL Boreham, D Lloyd International journal for parasitology 23 (1), 35-39, 1993 | 64 | 1993 |
A nuclear SH3 domain-binding protein that colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks G Craggs, PM Finan, D Lawson, J Wingfield, T Perera, S Gadher, NF Totty, ... Journal of Biological Chemistry 276 (32), 30552-30560, 2001 | 39 | 2001 |
Development of a homogeneous time-resolved fluorescence assay for high throughput screening to identify Lck inhibitors: comparison with scintillation proximity assay and … N Ohmi, JM Wingfield, H Yazawa, O Inagaki SLAS Discovery 5 (6), 463-470, 2000 | 34 | 2000 |
Identifying a species-specific region of yeast TFIIB in vivo SP Shaw, J Wingfield, MJ Dorsey, J Ma Molecular and cellular biology 16 (7), 3651-3657, 1996 | 32 | 1996 |
High-Throughput Screening Using Mass Spectrometry within Drug Discovery. M Rohman, J Wingfield High Throughput Screening Methods and Protocols 1439, 47-63, 2016 | 28 | 2016 |
Advances in mass spectrometry within drug discovery J Wingfield, ID Wilson Journal of Biomolecular Screening 21 (2), 109-110, 2016 | 16 | 2016 |
Acoustic mist ionization mass spectrometry for ultrahigh-throughput metabolomics screening MJ Smith, DP Ivanov, RJM Weber, J Wingfield, MR Viant Analytical Chemistry 93 (26), 9258-9266, 2021 | 14 | 2021 |
Information-rich high-throughput cellular assays using acoustic mist ionisation mass spectrometry M Bachman, I Sinclair, D Ivanov, J Wingfield Analyst 146 (1), 315-321, 2021 | 13 | 2021 |
What do we actually see in intracellular SERS? Investigating nanosensor-induced variation J Taylor, J Milton, M Willett, J Wingfield, S Mahajan Faraday Discussions 205, 409-428, 2017 | 12 | 2017 |
Increased activity of a model heterologous protein in Saccharomyces cerevisiae strains with reduced vacuolar proteinases JM Wingfield, JR Dickinson Applied microbiology and biotechnology 39, 211-215, 1993 | 10 | 1993 |
The activity of a model heterologous protein in pep4-3 mutants of Saccharomyces cerevisiae JM Wingfield, JR Dickinson Applied microbiology and biotechnology 36, 754-758, 1992 | 8 | 1992 |
A novel high-throughput FLIPR tetra–based method for capturing highly confluent kinetic data for structure–kinetic relationship guided early drug discovery P Khurana, L McWilliams, J Wingfield, D Barratt, B Srinivasan SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (5), 684-697, 2021 | 5 | 2021 |
High Throughput Screening: Methods and Protocols M Rohman, J Wingfield Methods Mol. Biol 1439, 47-63, 2016 | 5 | 2016 |
The cdc30 Mutation in Saccharomyces cerevisiae Affects Phosphoglucose Isomerase, the Cell Cycle and Sporulation JR Dickinson, ME Smith, TR Swanson, AS Williams, JM Wingfield Microbiology 134 (9), 2475-2480, 1988 | 5 | 1988 |
High-throughput mechanistic screening of non-equilibrium inhibitors by a fully automated data analysis pipeline in early drug-discovery B Srinivasan, JDF Weidinger, X Zhai, G Lemercier, T Ikeda, M Brewer, ... SLAS Discovery 27 (8), 460-470, 2022 | 4 | 2022 |