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Jonathan Wingfield
Jonathan Wingfield
Discovery Sciences, AstraZeneca
在 astrazeneca.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation
RA Ward, C Brassington, AL Breeze, A Caputo, S Critchlow, G Davies, ...
Journal of medicinal chemistry 55 (7), 3285-3306, 2012
1872012
Acoustic mist ionization platform for direct and contactless ultrahigh-throughput mass spectrometry analysis of liquid samples
I Sinclair, M Bachman, D Addison, M Rohman, DC Murray, G Davies, ...
Analytical chemistry 91 (6), 3790-3794, 2019
1182019
Novel acoustic loading of a mass spectrometer: toward next-generation high-throughput MS screening
I Sinclair, R Stearns, S Pringle, J Wingfield, S Datwani, E Hall, L Ghislain, ...
Journal of Laboratory Automation 21 (1), 19-26, 2016
1142016
Structure-based design of potent and selective inhibitors of the metabolic kinase PFKFB3
S Boyd, JL Brookfield, SE Critchlow, IA Cumming, NJ Curtis, J Debreczeni, ...
Journal of medicinal chemistry 58 (8), 3611-3625, 2015
972015
Nanopartiicles and intracellular applications of surface-enhanced Raman spectroscopy
jack taylor, anna heufner, L Li, jonathan wingfield, sumeet mahajan
Analyst 141, 5037-5055, 2016
952016
Oxygen affinities of metronidazole-resistant and-sensitive stocks of Giardia intestinalis
JE Ellis, JM Wingfield, D Cole, PFL Boreham, D Lloyd
International journal for parasitology 23 (1), 35-39, 1993
641993
A nuclear SH3 domain-binding protein that colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks
G Craggs, PM Finan, D Lawson, J Wingfield, T Perera, S Gadher, NF Totty, ...
Journal of Biological Chemistry 276 (32), 30552-30560, 2001
392001
Development of a homogeneous time-resolved fluorescence assay for high throughput screening to identify Lck inhibitors: comparison with scintillation proximity assay and …
N Ohmi, JM Wingfield, H Yazawa, O Inagaki
SLAS Discovery 5 (6), 463-470, 2000
342000
Identifying a species-specific region of yeast TFIIB in vivo
SP Shaw, J Wingfield, MJ Dorsey, J Ma
Molecular and cellular biology 16 (7), 3651-3657, 1996
321996
High-Throughput Screening Using Mass Spectrometry within Drug Discovery.
M Rohman, J Wingfield
High Throughput Screening Methods and Protocols 1439, 47-63, 2016
282016
Advances in mass spectrometry within drug discovery
J Wingfield, ID Wilson
Journal of Biomolecular Screening 21 (2), 109-110, 2016
162016
Acoustic mist ionization mass spectrometry for ultrahigh-throughput metabolomics screening
MJ Smith, DP Ivanov, RJM Weber, J Wingfield, MR Viant
Analytical Chemistry 93 (26), 9258-9266, 2021
142021
Information-rich high-throughput cellular assays using acoustic mist ionisation mass spectrometry
M Bachman, I Sinclair, D Ivanov, J Wingfield
Analyst 146 (1), 315-321, 2021
132021
What do we actually see in intracellular SERS? Investigating nanosensor-induced variation
J Taylor, J Milton, M Willett, J Wingfield, S Mahajan
Faraday Discussions 205, 409-428, 2017
122017
Increased activity of a model heterologous protein in Saccharomyces cerevisiae strains with reduced vacuolar proteinases
JM Wingfield, JR Dickinson
Applied microbiology and biotechnology 39, 211-215, 1993
101993
The activity of a model heterologous protein in pep4-3 mutants of Saccharomyces cerevisiae
JM Wingfield, JR Dickinson
Applied microbiology and biotechnology 36, 754-758, 1992
81992
A novel high-throughput FLIPR tetra–based method for capturing highly confluent kinetic data for structure–kinetic relationship guided early drug discovery
P Khurana, L McWilliams, J Wingfield, D Barratt, B Srinivasan
SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (5), 684-697, 2021
52021
High Throughput Screening: Methods and Protocols
M Rohman, J Wingfield
Methods Mol. Biol 1439, 47-63, 2016
52016
The cdc30 Mutation in Saccharomyces cerevisiae Affects Phosphoglucose Isomerase, the Cell Cycle and Sporulation
JR Dickinson, ME Smith, TR Swanson, AS Williams, JM Wingfield
Microbiology 134 (9), 2475-2480, 1988
51988
High-throughput mechanistic screening of non-equilibrium inhibitors by a fully automated data analysis pipeline in early drug-discovery
B Srinivasan, JDF Weidinger, X Zhai, G Lemercier, T Ikeda, M Brewer, ...
SLAS Discovery 27 (8), 460-470, 2022
42022
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