Prevention of atherosclerosis by bioactive palmitoleate through suppression of organelle stress and inflammasome activation I Çimen, B Kocatürk, S Koyuncu, Ö Tufanlı, UI Onat, AD Yıldırım, ... Science Translational Medicine 8 (358), 358ra126-358ra126, 2016 | 114 | 2016 |
The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington’s disease patients S Koyuncu, I Saez, HJ Lee, R Gutierrez-Garcia, W Pokrzywa, A Fatima, ... Nature communications 9 (1), 2886, 2018 | 96 | 2018 |
Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan A Noormohammadi, A Khodakarami, R Gutierrez-Garcia, HJ Lee, ... Nature communications 7 (1), 13649, 2016 | 86 | 2016 |
Rewiring of the ubiquitinated proteome determines ageing in C. elegans S Koyuncu, R Loureiro, HJ Lee, P Wagle, M Krueger, D Vilchez Nature 596 (7871), 285-290, 2021 | 75 | 2021 |
DNAJB6, a key factor in neuronal sensitivity to amyloidogenesis A Thiruvalluvan, EP de Mattos, JF Brunsting, R Bakels, D Serlidaki, ... Molecular cell 78 (2), 346-358. e9, 2020 | 66 | 2020 |
Proteostasis of huntingtin in health and disease S Koyuncu, A Fatima, R Gutierrez-Garcia, D Vilchez International journal of molecular sciences 18 (7), 1568, 2017 | 60 | 2017 |
Insights into the ubiquitin-proteasome system of human embryonic stem cells I Saez, S Koyuncu, R Gutierrez-Garcia, C Dieterich, D Vilchez Scientific reports 8 (1), 4092, 2018 | 50 | 2018 |
Mechanisms of protein homeostasis (proteostasis) maintain stem cell identity in mammalian pluripotent stem cells A Noormohammadi, G Calculli, R Gutierrez-Garcia, A Khodakarami, ... Cellular and Molecular Life Sciences 75, 275-290, 2018 | 50 | 2018 |
Prostaglandin signals from adult germline stem cells delay somatic ageing of Caenorhabditis elegans HJ Lee, A Noormohammadi, S Koyuncu, G Calculli, MS Simic, M Herholz, ... Nature metabolism 1 (8), 790-810, 2019 | 30 | 2019 |
The E3 ubiquitin ligase UBR 5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells I Saez, JV Gerbracht, S Koyuncu, HJ Lee, M Horn, V Kroef, MS Denzel, ... FEBS letters 594 (1), 175-188, 2020 | 26 | 2020 |
Cold temperature extends longevity and prevents disease-related protein aggregation through PA28γ-induced proteasomes HJ Lee, H Alirzayeva, S Koyuncu, A Rueber, A Noormohammadi, ... Nature Aging 3 (5), 546-566, 2023 | 22 | 2023 |
Insights Into the Links Between Proteostasis and Aging From C. elegans WH Zhang, S Koyuncu, D Vilchez Frontiers in Aging 3, 854157, 2022 | 14 | 2022 |
Arabidopsis metacaspase MC1 localizes in stress granules, clears protein aggregates, and delays senescence N Ruiz-Solaní, J Salguero-Linares, L Armengot, J Santos, I Pallarès, ... The Plant Cell 35 (9), 3325-3344, 2023 | 10 | 2023 |
Defining the general principles of stem cell aging: lessons from organismal models S Koyuncu, D Irmak, I Saez, D Vilchez Current Stem Cell Reports 1, 162-169, 2015 | 8 | 2015 |
G3BP1-dependent mechanism suppressing protein aggregation in Huntington’s models and its demise upon stress granule assembly R Gutiérrez-Garcia, S Koyuncu, F Hommen, S Bilican, HJ Lee, A Fatima, ... Human molecular genetics 32 (10), 1607-1621, 2023 | 7 | 2023 |
In planta expression of human polyQ-expanded huntingtin fragment reveals mechanisms to prevent disease-related protein aggregation E Llamas, S Koyuncu, HJ Lee, M Wehrmann, R Gutierrez-Garcia, ... Nature aging 3 (11), 1345-1357, 2023 | 5 | 2023 |
Chloroplast protein import determines plant proteostasis and retrograde signaling E Llamas, S Koyuncu, HJ Lee, R Gutierrez-Garcia, N Dunken, N Charura, ... BioRxiv, 2022.03. 19.484971, 2022 | 3 | 2022 |
The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ X Li, I Hernandez, S Koyuncu, B Kis, M Häggblad, L Lidemalm, AA Abbas, ... EBioMedicine 103, 2024 | 1 | 2024 |
Author Correction: The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington’s disease patients S Koyuncu, I Saez, HJ Lee, R Gutierrez-Garcia, W Pokrzywa, A Fatima, ... Nature Communications 11, 2020 | 1 | 2020 |
Author Correction: Rewiring of the ubiquitinated proteome determines ageing in C. elegans S Koyuncu, R Loureiro, HJ Lee, P Wagle, M Krueger, D Vilchez Nature 626 (8001), E20-E20, 2024 | | 2024 |