Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells DA Jackson, A Pombo The Journal of cell biology 140 (6), 1285-1295, 1998 | 954 | 1998 |
Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations MR Branco, A Pombo PLoS biology 4 (5), e138, 2006 | 859 | 2006 |
Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells JK Stock, S Giadrossi, M Casanova, E Brookes, M Vidal, H Koseki, ... Nature cell biology 9 (12), 1428-1435, 2007 | 763 | 2007 |
Complex multi-enhancer contacts captured by genome architecture mapping RA Beagrie, A Scialdone, M Schueler, DCA Kraemer, M Chotalia, SQ Xie, ... Nature 543 (7646), 519-524, 2017 | 691 | 2017 |
Formation of new chromatin domains determines pathogenicity of genomic duplications M Franke, DM Ibrahim, G Andrey, W Schwarzer, V Heinrich, R Schöpflin, ... Nature 538 (7624), 265-269, 2016 | 685 | 2016 |
Three-dimensional genome architecture: players and mechanisms A Pombo, N Dillon Nature reviews Molecular cell biology 16 (4), 245-257, 2015 | 617 | 2015 |
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells E Arner, CO Daub, K Vitting-Seerup, R Andersson, B Lilje, F Drabløs, ... Science 347 (6225), 1010-1014, 2015 | 605 | 2015 |
Complexity of chromatin folding is captured by the strings and binders switch model M Barbieri, M Chotalia, J Fraser, LM Lavitas, J Dostie, A Pombo, ... Proceedings of the National Academy of Sciences 109 (40), 16173-16178, 2012 | 567 | 2012 |
Dendritic cells interact directly with naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent response M Wykes, A Pombo, C Jenkins, GG MacPherson The Journal of Immunology 161 (3), 1313-1319, 1998 | 564 | 1998 |
Active RNA polymerases are localized within discrete transcription ‘factories’ in human nuclei FJ Iborra, A Pombo, DA Jackson, PR Cook Journal of cell science 109 (6), 1427-1436, 1996 | 556 | 1996 |
Methods for mapping 3D chromosome architecture R Kempfer, A Pombo Nature Reviews Genetics 21 (4), 207-226, 2020 | 459 | 2020 |
Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2 A Kanhere, K Viiri, CC Araújo, J Rasaiyaah, RD Bouwman, WA Whyte, ... Molecular cell 38 (5), 675-688, 2010 | 453 | 2010 |
Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment HQ Le, S Ghatak, CYC Yeung, F Tellkamp, C Günschmann, C Dieterich, ... Nature cell biology 18 (8), 864-875, 2016 | 439 | 2016 |
Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation J Fraser, C Ferrai, AM Chiariello, M Schueler, T Rito, G Laudanno, ... Molecular systems biology 11 (12), 852, 2015 | 375 | 2015 |
Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators D Landeira, S Sauer, R Poot, M Dvorkina, L Mazzarella, HF Jørgensen, ... Nature cell biology 12 (6), 618-624, 2010 | 344 | 2010 |
Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs E Brookes, I de Santiago, D Hebenstreit, KJ Morris, T Carroll, SQ Xie, ... Cell stem cell 10 (2), 157-170, 2012 | 317 | 2012 |
Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III A Pombo, DA Jackson, M Hollinshead, Z Wang, RG Roeder, PR Cook The EMBO journal, 1999 | 311 | 1999 |
Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes TL McDowell, RJ Gibbons, H Sutherland, DM O’Rourke, WA Bickmore, ... Proceedings of the National Academy of Sciences 96 (24), 13983-13988, 1999 | 303 | 1999 |
FANTOM5 CAGE profiles of human and mouse samples S Noguchi, T Arakawa, S Fukuda, M Furuno, A Hasegawa, F Hori, ... Scientific data 4 (1), 1-10, 2017 | 232 | 2017 |
Variant histone H3. 3 marks promoters of transcriptionally active genes during mammalian cell division CM Chow, A Georgiou, H Szutorisz, A Maia e Silva, A Pombo, I Barahona, ... EMBO reports 6 (4), 354-360, 2005 | 229 | 2005 |