| A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration P Koch, T Opitz, JA Steinbeck, J Ladewig, O Brüstle Proceedings of the National Academy of Sciences 106 (9), 3225-3230, 2009 | 607 | 2009 |
| Direct conversion of fibroblasts into stably expandable neural stem cells M Thier, P Wörsdörfer, YB Lakes, R Gorris, S Herms, T Opitz, D Seiferling, ... Cell stem cell 10 (4), 473-479, 2012 | 602 | 2012 |
| Global ischemia induces downregulation of Glur2 mRNA and increases AMPA receptor-mediated Ca2+ influx in hippocampal CA1 neurons of gerbil JA Gorter, JJ Petrozzino, EM Aronica, DM Rosenbaum, T Opitz, ... Journal of Neuroscience 17 (16), 6179-6188, 1997 | 370 | 1997 |
| Inhibition of Notch Signaling in Human Embryonic Stem Cell–Derived Neural Stem Cells Delays G1/S Phase Transition and Accelerates Neuronal Differentiation In Vitro and … L Borghese, D Dolezalova, T Opitz, S Haupt, A Leinhaas, B Steinfarz, ... Stem cells 28 (5), 955-964, 2010 | 293 | 2010 |
| mGluR1-mediated potentiation of NMDA receptors involves a rise in intracellular calcium and activation of protein kinase C VA Skeberdis, J Lan, T Opitz, X Zheng, MVL Bennett, RS Zukin Neuropharmacology 40 (7), 856-865, 2001 | 243 | 2001 |
| Transcriptional upregulation of Cav3. 2 mediates epileptogenesis in the pilocarpine model of epilepsy AJ Becker, J Pitsch, D Sochivko, T Opitz, M Staniek, CC Chen, ... Journal of Neuroscience 28 (49), 13341-13353, 2008 | 236 | 2008 |
| Spontaneous development of synchronous oscillatory activity during maturation of cortical networks in vitro T Opitz, AD De Lima, T Voigt Journal of neurophysiology 88 (5), 2196-2206, 2002 | 213 | 2002 |
| Status epilepticus decreases glutamate receptor 2 mRNA and protein expression in hippocampal pyramidal cells before neuronal death SY Grooms, T Opitz, MVL Bennett, RS Zukin Proceedings of the National Academy of Sciences 97 (7), 3631-3636, 2000 | 172 | 2000 |
| Synchronous oscillatory activity in immature cortical network is driven by GABAergic preplate neurons T Voigt, T Opitz, AD de Lima Journal of Neuroscience 21 (22), 8895-8905, 2001 | 122 | 2001 |
| Inhibition of different pathways influencing Na+ homeostasis protects organotypic hippocampal slice cultures from hypoxic/hypoglycemic injury J Breder, CF Sabelhaus, T Opitz, KG Reymann, UH Schröder Neuropharmacology 39 (10), 1779-1787, 2000 | 114 | 2000 |
| An increase in persistent sodium current contributes to intrinsic neuronal bursting after status epilepticus S Chen, H Su, C Yue, S Remy, M Royeck, D Sochivko, T Opitz, H Beck, ... Journal of neurophysiology 105 (1), 117-129, 2011 | 104 | 2011 |
| Activation of early silent synapses by spontaneous synchronous network activity limits the range of neocortical connections T Voigt, T Opitz, AD de Lima Journal of Neuroscience 25 (18), 4605-4615, 2005 | 95 | 2005 |
| Efficacy loss of the anticonvulsant carbamazepine in mice lacking sodium channel β subunits via paradoxical effects on persistent sodium currents M Uebachs, T Opitz, M Royeck, G Dickhof, MT Horstmann, LL Isom, ... Journal of Neuroscience 30 (25), 8489-8501, 2010 | 92 | 2010 |
| Metabotropic glutamate receptor agonist DCG-IV as NMDA receptor agonist in immature rat hippocampal neurons VW Wilsch, VI Pidoplichko, T Opitz, H Shinozaki, KG Reymann European journal of pharmacology 262 (3), 287-291, 1994 | 80 | 1994 |
| Irreversible loss of a subpopulation of cortical interneurons in the absence of glutamatergic network activity AD De Lima, T Opitz, T Voigt European Journal of Neuroscience 19 (11), 2931-2943, 2004 | 76 | 2004 |
| Adult germ line stem cells as a source of functional neurons and glia T Glaser, T Opitz, T Kischlat, R Konang, P Sasse, BK Fleischmann, ... Stem Cells 26 (9), 2434-2443, 2008 | 56 | 2008 |
| Zinc regulates a key transcriptional pathway for epileptogenesis via metal-regulatory transcription factor 1 KMJ Van Loo, C Schaub, J Pitsch, R Kulbida, T Opitz, D Ekstein, A Dalal, ... Nature Communications 6 (1), 1-12, 2015 | 55 | 2015 |
| Protective effect of group I metabotropic glutamate receptor activation against hypoxic/hypoglycemic injury in rat hippocampal slices: timing and involvement of protein kinase C UH Schröder, T Opitz, T Jäger, CF Sabelhaus, J Breder, KG Reymann Neuropharmacology 38 (2), 209-216, 1999 | 55 | 1999 |
| The metabotropic glutamate receptor antagonist (+)-α-methyl-4-carboxyphenylglycine protects hippocampal CA1 neurons of the rat from in vitro hypoxia/hypoglycemia T Opitz, P Richter, KG Reymann Neuropharmacology 33 (5), 715-717, 1994 | 54 | 1994 |
| Lineage selection of functional and cryopreservable human embryonic stem cell‐derived neurons J Ladewig, P Koch, E Endl, B Meiners, T Opitz, S Couillard‐Despres, ... Stem cells 26 (7), 1705-1712, 2008 | 53 | 2008 |
