Dual proteome-scale networks reveal cell-specific remodeling of the human interactome EL Huttlin, RJ Bruckner, J Navarrete-Perea, JR Cannon, K Baltier, ... Cell 184 (11), 3022-3040. e28, 2021 | 622 | 2021 |
Modular organization and assembly of SWI/SNF family chromatin remodeling complexes N Mashtalir, AR D’Avino, BC Michel, J Luo, J Pan, JE Otto, HJ Zullow, ... Cell 175 (5), 1272-1288. e20, 2018 | 583 | 2018 |
Accurate proteome-wide missense variant effect prediction with AlphaMissense J Cheng, G Novati, J Pan, C Bycroft, A Žemgulytė, T Applebaum, A Pritzel, ... Science 381 (6664), eadg7492, 2023 | 368 | 2023 |
A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation BC Michel, AR D’Avino, SH Cassel, N Mashtalir, ZM McKenzie, ... Nature cell biology 20 (12), 1410-1420, 2018 | 329 | 2018 |
Extracting biological insights from the project achilles genome-scale CRISPR screens in cancer cell lines JM Dempster, J Rossen, M Kazachkova, J Pan, G Kugener, DE Root, ... BioRxiv, 720243, 2019 | 311 | 2019 |
Interrogation of mammalian protein complex structure, function, and membership using genome-scale fitness screens J Pan, RM Meyers, BC Michel, N Mashtalir, AE Sizemore, JN Wells, ... Cell systems 6 (5), 555-568. e7, 2018 | 142 | 2018 |
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity–independent genomic targeting J Pan, ZM McKenzie, AR D’Avino, N Mashtalir, CA Lareau, R St. Pierre, ... Nature genetics 51 (4), 618-626, 2019 | 103 | 2019 |
Binding of TMPRSS2-ERG to BAF chromatin remodeling complexes mediates prostate oncogenesis GJ Sandoval, JL Pulice, H Pakula, M Schenone, DY Takeda, M Pop, ... Molecular cell 71 (4), 554-566. e7, 2018 | 98 | 2018 |
CRISPR/Cas9‐directed genome editing of cultured cells L Yang, JL Yang, S Byrne, J Pan, GM Church Current protocols in molecular biology 107 (1), 31.1. 1-31.1. 17, 2014 | 97 | 2014 |
Synthetic lethal interaction of SHOC2 depletion with MEK inhibition in RAS-driven cancers R Sulahian, JJ Kwon, KH Walsh, E Pailler, TL Bosse, M Thaker, ... Cell reports 29 (1), 118-134. e8, 2019 | 75 | 2019 |
Structure–function analysis of the SHOC2–MRAS–PP1C holophosphatase complex JJ Kwon, B Hajian, Y Bian, LC Young, AJ Amor, JR Fuller, CV Fraley, ... Nature 609 (7926), 408-415, 2022 | 46 | 2022 |
Sparse dictionary learning recovers pleiotropy from human cell fitness screens J Pan, JJ Kwon, JA Talamas, AA Borah, F Vazquez, JS Boehm, ... Cell systems 13 (4), 286-303. e10, 2022 | 22 | 2022 |
New directions: enduring ozone N Unger, JL Pan Atmospheric environment 55, 456-458, 2012 | 9 | 2012 |
“Hacking” Our Way across Interdisciplinary Boundaries J Pan, K Johnson Cell systems 8 (5), 361-362, 2019 | 2 | 2019 |
On knowing a gene: A distributional hypothesis of gene function JJ Kwon, J Pan, G Gonzalez, WC Hahn, M Zitnik Cell Systems, 2024 | 1 | 2024 |
BioPlexR and BioPlexPy: integrated data products for the analysis of human protein interactions L Geistlinger, R Vargas Jr, T Lee, J Pan, EL Huttlin, R Gentleman Bioinformatics 39 (3), btad091, 2023 | | 2023 |