| New insights into the role of TREM2 in Alzheimer’s disease M Gratuze, CEG Leyns, DM Holtzman Molecular neurodegeneration 13 (1), 66, 2018 | 413 | 2018 |
| TREM2 function impedes tau seeding in neuritic plaques CEG Leyns, M Gratuze, S Narasimhan, N Jain, LJ Koscal, H Jiang, ... Nature neuroscience 22 (8), 1217-1222, 2019 | 235 | 2019 |
| Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia C Wang, M Xiong, M Gratuze, X Bao, Y Shi, PS Andhey, M Manis, ... Neuron 109 (10), 1657-1674. e7, 2021 | 188 | 2021 |
| Impact of TREM2R47H variant on tau pathology–induced gliosis and neurodegeneration M Gratuze, CEG Leyns, AD Sauerbeck, MK St-Pierre, M Xiong, N Kim, ... The Journal of clinical investigation 130 (9), 4954-4968, 2020 | 165 | 2020 |
| Insulin dysfunction and Tau pathology NB El Khoury, M Gratuze, MA Papon, A Bretteville, E Planel Frontiers in cellular neuroscience 8, 22, 2014 | 143 | 2014 |
| Activated microglia mitigate Aβ-associated tau seeding and spreading M Gratuze, Y Chen, S Parhizkar, N Jain, MR Strickland, JR Serrano, ... Journal of Experimental Medicine 218 (8), e20210542, 2021 | 115 | 2021 |
| APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function M Xiong, H Jiang, JR Serrano, ER Gonzales, C Wang, M Gratuze, ... Science translational medicine 13 (581), eabd7522, 2021 | 100 | 2021 |
| Is Huntington's disease a tauopathy? M Gratuze, G Cisbani, F Cicchetti, E Planel Brain 139 (4), 1014-1025, 2016 | 79 | 2016 |
| Insulin deprivation induces PP2A inhibition and tau hyperphosphorylation in hTau mice, a model of Alzheimer’s disease-like tau pathology M Gratuze, J Julien, FR Petry, F Morin, E Planel Scientific reports 7 (1), 46359, 2017 | 72 | 2017 |
| Tau hyperphosphorylation and deregulation of calcineurin in mouse models of Huntington's disease M Gratuze, A Noël, C Julien, G Cisbani, P Milot-Rousseau, F Morin, ... Human Molecular Genetics 24 (1), 86-99, 2015 | 64 | 2015 |
| Arterial stiffness due to carotid calcification disrupts cerebral blood flow regulation and leads to cognitive deficits G Muhire, MF Iulita, D Vallerand, J Youwakim, M Gratuze, FR Petry, ... Journal of the American Heart Association 8 (9), e011630, 2019 | 53 | 2019 |
| Tau hyperphosphorylation in the brain of ob/ob mice is due to hypothermia: Importance of thermoregulation in linking diabetes and Alzheimer's disease M Gratuze, NB El Khoury, A Turgeon, C Julien, F Marcouiller, F Morin, ... Neurobiology of disease 98, 1-8, 2017 | 50 | 2017 |
| Hypothermia mediates age-dependent increase of tau phosphorylation in db/db mice NB El Khoury, M Gratuze, F Petry, MA Papon, C Julien, F Marcouiller, ... Neurobiology of disease 88, 55-65, 2016 | 44 | 2016 |
| Dexmedetomidine increases tau phosphorylation under normothermic conditions in vivo and in vitro RA Whittington, L Virág, M Gratuze, FR Petry, A Noël, I Poitras, G Truchetti, ... Neurobiology of aging 36 (8), 2414-2428, 2015 | 43 | 2015 |
| TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4 M Gratuze, JCM Schlachetzki, RDO Albanus, N Jain, B Novotny, L Brase, ... Neuron 111 (2), 202-219. e7, 2023 | 39 | 2023 |
| SEQUIN multiscale imaging of mammalian central synapses reveals loss of synaptic connectivity resulting from diffuse traumatic brain injury AD Sauerbeck, M Gangolli, SJ Reitz, MH Salyards, SH Kim, ... Neuron 107 (2), 257-273. e5, 2020 | 38 | 2020 |
| Circadian and sleep/wake-dependent variations in tau phosphorylation are driven by temperature I Guisle, M Gratuze, S Petry, F Morin, R Keraudren, RA Whittington, ... Sleep 43 (4), zsz266, 2020 | 38 | 2020 |
| Mutual relationship between tau and central insulin signalling: consequences for AD and tauopathies? M Gratuze, A Joly-Amado, D Vieau, L Buee, D Blum Neuroendocrinology 107 (2), 181-195, 2018 | 38 | 2018 |
| High-fat, high-sugar, and high-cholesterol consumption does not impact tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathology M Gratuze, J Julien, F Morin, F Calon, SS Hébert, A Marette, E Planel Neurobiology of Aging 47, 71-73, 2016 | 33 | 2016 |
| Differential effects of voluntary treadmill exercise and caloric restriction on tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathology fed with Western diet M Gratuze, J Julien, F Morin, A Marette, E Planel Progress in Neuro-Psychopharmacology and Biological Psychiatry 79, 452-461, 2017 | 32 | 2017 |
