Donor cell leukemia: a review DH Wiseman Biology of Blood and Marrow Transplantation 17 (6), 771-789, 2011 | 206 | 2011 |
Mutations in TRNT1 cause congenital sideroblastic anemia with immunodeficiency, fevers, and developmental delay (SIFD) PK Chakraborty, K Schmitz-Abe, EK Kennedy, H Mamady, T Naas, ... Blood, The Journal of the American Society of Hematology 124 (18), 2867-2871, 2014 | 194 | 2014 |
Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, ... Nature 574 (7777), 273-277, 2019 | 184 | 2019 |
Enhancer activation by pharmacologic displacement of LSD1 from GFI1 induces differentiation in acute myeloid leukemia A Maiques-Diaz, GJ Spencer, JT Lynch, F Ciceri, EL Williams, ... Cell reports 22 (13), 3641-3659, 2018 | 180 | 2018 |
Reversible inhibitors of LSD1 as therapeutic agents in acute myeloid leukemia: clinical significance and progress to date DP Mould, AE McGonagle, DH Wiseman, EL Williams, AM Jordan Medicinal research reviews 35 (3), 586-618, 2015 | 170 | 2015 |
A novel syndrome of congenital sideroblastic anemia, B-cell immunodeficiency, periodic fevers, and developmental delay (SIFD) DH Wiseman, A May, S Jolles, P Connor, C Powell, MM Heeney, ... Blood, The Journal of the American Society of Hematology 122 (1), 112-123, 2013 | 115 | 2013 |
SF3B1 mutations induce R-loop accumulation and DNA damage in MDS and leukemia cells with therapeutic implications S Singh, D Ahmed, H Dolatshad, D Tatwavedi, U Schulze, A Sanchi, ... Leukemia 34 (9), 2525-2530, 2020 | 79 | 2020 |
Frequent derepression of the mesenchymal transcription factor gene FOXC1 in acute myeloid leukemia TDD Somerville, DH Wiseman, GJ Spencer, X Huang, JT Lynch, ... Cancer cell 28 (3), 329-342, 2015 | 68 | 2015 |
CD86 expression as a surrogate cellular biomarker for pharmacological inhibition of the histone demethylase lysine-specific demethylase 1 JT Lynch, MJ Cockerill, JR Hitchin, DH Wiseman, TCP Somervaille Analytical biochemistry 442 (1), 104-106, 2013 | 62 | 2013 |
The variety of leukemic stem cells in myeloid malignancy DH Wiseman, BF Greystoke, TCP Somervaille Oncogene 33 (24), 3091-3098, 2014 | 61 | 2014 |
Discovery and optimization of allosteric inhibitors of mutant isocitrate dehydrogenase 1 (R132H IDH1) displaying activity in human acute myeloid leukemia cells S Jones, J Ahmet, K Ayton, M Ball, M Cockerill, E Fairweather, N Hamilton, ... Journal of Medicinal Chemistry 59 (24), 11120-11137, 2016 | 53 | 2016 |
Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms J Taylor, X Mi, K North, M Binder, A Penson, T Lasho, K Knorr, ... Blood, The Journal of the American Society of Hematology 136 (13), 1477-1486, 2020 | 50 | 2020 |
Management of mucopolysaccharidosis type IH (Hurler’s syndrome) presenting in infancy with severe dilated cardiomyopathy: a single institution’s experience DH Wiseman, J Mercer, K Tylee, N Malaiya, DK Bonney, SA Jones, ... Journal of inherited metabolic disease 36, 263-270, 2013 | 41 | 2013 |
Divergent clonal evolution of blastic plasmacytoid dendritic cell neoplasm and chronic myelomonocytic leukemia from a shared TET2-mutated origin K Batta, HM Bossenbroek, N Pemmaraju, DP Wilks, R Chasty, M Dennis, ... Leukemia 35 (11), 3299-3303, 2021 | 26 | 2021 |
The dynamic interface between the bone marrow vascular niche and hematopoietic stem cells in myeloid malignancy L Mosteo, J Storer, K Batta, EJ Searle, D Duarte, DH Wiseman Frontiers in cell and developmental biology 9, 635189, 2021 | 23 | 2021 |
Guidelines for the management of adult myelodysplastic syndromes SB Killick, W Ingram, D Culligan, H Enright, J Kell, EM Payne, ... British journal of haematology 194 (2), 267-281, 2021 | 22 | 2021 |
Chronic myelomonocytic leukaemia stem cell transcriptomes anticipate disease morphology and outcome DH Wiseman, SM Baker, AV Dongre, K Gurashi, JA Storer, ... EBioMedicine 58, 2020 | 20 | 2020 |
Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils HH Encabo, IV Aramburu, M Garcia-Albornoz, M Piganeau, H Wood, ... Cell stem cell 30 (6), 781-799. e9, 2023 | 17 | 2023 |
Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia F Simeoni, I Romero-Camarero, F Camera, FMR Amaral, OJ Sinclair, ... Cell Reports 36 (12), 2021 | 17 | 2021 |
Frequent reconstitution of IDH2R140Q mutant clonal multilineage hematopoiesis following chemotherapy for acute myeloid leukemia DH Wiseman, EL Williams, DP Wilks, H Sun Leong, TDD Somerville, ... Leukemia 30 (9), 1946-1950, 2016 | 17 | 2016 |