Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders T Ernst, AJ Chase, J Score, CE Hidalgo-Curtis, C Bryant, AV Jones, ... Nature genetics 42 (8), 722-726, 2010 | 1410 | 2010 |
Mutations and prognosis in primary myelofibrosis AM Vannucchi, TL Lasho, P Guglielmelli, F Biamonte, A Pardanani, ... Leukemia 27 (9), 1861-1869, 2013 | 906 | 2013 |
The number of prognostically detrimental mutations and prognosis in primary myelofibrosis: an international study of 797 patients P Guglielmelli, TL Lasho, G Rotunno, J Score, C Mannarelli, A Pancrazzi, ... Leukemia 28 (9), 1804-1810, 2014 | 362 | 2014 |
EZH2 mutational status predicts poor survival in myelofibrosis P Guglielmelli, F Biamonte, J Score, C Hidalgo-Curtis, F Cervantes, ... Blood, The Journal of the American Society of Hematology 118 (19), 5227-5234, 2011 | 312 | 2011 |
How common are myeloproliferative neoplasms? A systematic review and meta‐analysis GJ Titmarsh, AS Duncombe, MF McMullin, M O'Rorke, R Mesa, ... American journal of hematology 89 (6), 581-587, 2014 | 304 | 2014 |
Attempts to optimize induction and consolidation treatment in acute myeloid leukemia: results of the MRC AML12 trial AK Burnett, RK Hills, DW Milligan, AH Goldstone, AG Prentice, ... Journal of clinical oncology 28 (4), 586-595, 2010 | 267 | 2010 |
A multicentre, open, non‐comparative phase II study of a combination of fludarabine phosphate, cytarabine and granulocyte colony‐stimulating factor in relapsed and refractory … G Jackson, P Taylor, GM Smith, R Marcus, A Smith, P Chu, TJ Littlewood, ... British journal of haematology 112 (1), 127-137, 2001 | 200 | 2001 |
Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms W Tapper, AV Jones, R Kralovics, AS Harutyunyan, K Zoi, W Leung, ... Nature communications 6 (1), 6691, 2015 | 195 | 2015 |
Guideline for the investigation and management of eosinophilia N Butt, J Lambert, S Ali, P Beer, N Cross, A Duncombe, J Ewing, ... British journal of haematology 176 (4), 2017 | 188 | 2017 |
Guideline for the diagnosis and management of myelofibrosis JT Reilly, MF McMullin, PA Beer, N Butt, E Conneally, A Duncombe, ... British journal of haematology 158 (4), 453-471, 2012 | 139 | 2012 |
The SF3B1 inhibitor spliceostatin A (SSA) elicits apoptosis in chronic lymphocytic leukaemia cells through downregulation of Mcl-1 M Larrayoz, SJ Blakemore, RC Dobson, MD Blunt, MJJ Rose-Zerilli, ... Leukemia 30 (2), 351-360, 2016 | 114 | 2016 |
Tumor necrosis factor mediates autocrine growth inhibition in a chronic leukemia. AS Duncombe, HE Heslop, M Turner, A Meager, R Priest, T Exley, ... Journal of immunology (Baltimore, Md.: 1950) 143 (11), 3828-3834, 1989 | 111 | 1989 |
Recurrent activating STAT5B N642H mutation in myeloid neoplasms with eosinophilia NCP Cross, Y Hoade, WJ Tapper, G Carreno-Tarragona, T Fanelli, ... Leukemia 33 (2), 415-425, 2019 | 87 | 2019 |
Mechanisms and clinical significance of BIM phosphorylation in chronic lymphocytic leukemia A Paterson, CI Mockridge, JE Adams, S Krysov, KN Potter, AS Duncombe, ... Blood, The Journal of the American Society of Hematology 119 (7), 1726-1736, 2012 | 69 | 2012 |
Fatal disseminated fusarium infection in acute lymphoblastic leukaemia in complete remission B Austen, H McCarthy, B Wilkins, A Smith, A Duncombe Journal of clinical pathology 54 (6), 488-490, 2001 | 63 | 2001 |
Structural and functional features of the B-cell receptor in IgG-positive chronic lymphocytic leukemia KN Potter, CI Mockridge, L Neville, I Wheatley, M Schenk, J Orchard, ... Clinical cancer research 12 (6), 1672-1679, 2006 | 57 | 2006 |
Environmental, lifestyle, and familial/ethnic factors associated with myeloproliferative neoplasms LA Anderson, AS Duncombe, M Hughes, ME Mills, JC Wilson, ... American journal of hematology 87 (2), 175-182, 2012 | 54 | 2012 |
The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the Eµ-TCL1 mouse model MD Blunt, MJ Carter, M Larrayoz, LD Smith, M Aguilar-Hernandez, ... Blood, The Journal of the American Society of Hematology 125 (26), 4032-4041, 2015 | 53 | 2015 |
Immunity against Pseudomonas aeruginosa adoptively transferred to bone marrow transplant recipients DJ Gottlieb, SJJ Cryz, E Furer, JU Que, HG Prentice, AS Duncombe, ... | 51 | 1990 |
Use of JAK inhibitors in the management of myelofibrosis: a revision of the British Committee for Standards in Haematology Guidelines for Investigation and Management of … JT Reilly, MF McMullin, PA Beer, N Butt, E Conneally, AS Duncombe, ... British journal of haematology 167 (3), 418-420, 2014 | 49 | 2014 |