Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion T Dayeh, P Volkov, S Salö, E Hall, E Nilsson, AH Olsson, CL Kirkpatrick, ... PLoS genetics 10 (3), e1004160, 2014 | 554 | 2014 |
Increased DNA Methylation and Decreased Expression of PDX-1 in Pancreatic Islets from Patients with Type 2 Diabetes BT Yang, TA Dayeh, PA Volkov, CL Kirkpatrick, S Malmgren, X Jing, ... Molecular endocrinology 26 (7), 1203-1212, 2012 | 338 | 2012 |
Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA 1c levels in human pancreatic islets BT Yang, TA Dayeh, CL Kirkpatrick, J Taneera, R Kumar, L Groop, ... Diabetologia 54 (2), 360-367, 2011 | 314 | 2011 |
A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets P Marchetti, R Lupi, M Bugliani, CL Kirkpatrick, G Sebastiani, FA Grieco, ... Diabetologia 55 (12), 3262-3272, 2012 | 293 | 2012 |
Selective Actions of Mitochondrial Fission/Fusion Genes on Metabolism-Secretion Coupling in Insulin-releasing Cells*♦ KS Park, A Wiederkehr, C Kirkpatrick, Y Mattenberger, JC Martinou, ... Journal of Biological Chemistry 283 (48), 33347-33356, 2008 | 131 | 2008 |
DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets E Hall, T Dayeh, CL Kirkpatrick, CB Wollheim, MD Nitert, C Ling BMC medical genetics 14 (1), 1-7, 2013 | 127 | 2013 |
Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin–proteasome system in pancreatic beta cell dysfunction M Bugliani, R Liechti, H Cheon, M Suleiman, L Marselli, C Kirkpatrick, ... Molecular and cellular endocrinology 367 (1-2), 1-10, 2013 | 102 | 2013 |
Decoding Caulobacter development CL Kirkpatrick, PH Viollier FEMS microbiology reviews 36 (1), 193-205, 2012 | 72 | 2012 |
Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors CL Kirkpatrick, P Marchetti, F Purrello, S Piro, M Bugliani, D Bosco, ... PloS one 5 (6), e11053, 2010 | 70 | 2010 |
Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells S Epstein, CL Kirkpatrick, GA Castillon, M Muñiz, I Riezman, FPA David, ... Journal of lipid research 53 (3), 412-420, 2012 | 56 | 2012 |
New (s) to the (Z-) ring CL Kirkpatrick, PH Viollier Current opinion in microbiology 14 (6), 691-697, 2011 | 48 | 2011 |
Poles apart: prokaryotic polar organelles and their spatial regulation CL Kirkpatrick, PH Viollier Cold Spring Harbor Perspectives in Biology 3 (3), a006809, 2011 | 39 | 2011 |
Hepatic nuclear factor 1α (HNF1α) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes β-cells to endoplasmic reticulum stress CL Kirkpatrick, A Wiederkehr, M Baquié, D Akhmedov, H Wang, ... Journal of Biological Chemistry 286 (37), 32300-32312, 2011 | 30 | 2011 |
Mitochondrial Dysfunction Contributes to Impaired Insulin Secretion in INS-1 Cells with Dominant-negative Mutations of HNF-1α and in HNF-1α-deficient Islets RL Pongratz, RG Kibbey, CL Kirkpatrick, X Zhao, M Pontoglio, M Yaniv, ... Journal of Biological Chemistry 284 (25), 16808-16821, 2009 | 30 | 2009 |
Cell dispersal in biofilms: an extracellular DNA masks nature's strongest glue CL Kirkpatrick, PH Viollier Molecular microbiology 77 (4), 801-804, 2010 | 25 | 2010 |
Growth control switch by a DNA-damage-inducible toxin–antitoxin system in Caulobacter crescentus CL Kirkpatrick, D Martins, P Redder, A Frandi, J Mignolet, JB Chapalay, ... Nature microbiology 1 (4), 1-10, 2016 | 24 | 2016 |
Synthetic interaction between the TipN polarity factor and an AcrAB-family efflux pump implicates cell polarity in bacterial drug resistance CL Kirkpatrick, PH Viollier Chemistry & biology 21 (5), 657-665, 2014 | 24 | 2014 |
There is no hiding if you Seq: recent breakthroughs in Pseudomonas aeruginosa research revealed by genomic and transcriptomic next-generation sequencing RXE Valli, M Lyng, CL Kirkpatrick Journal of medical microbiology 69 (2), 162-175, 2020 | 17 | 2020 |
Loss of bacterial cell pole stabilization in caulobacter crescentus sensitizes to outer membrane stress and peptidoglycan-directed antibiotics SU Vallet, LH Hansen, FC Bistrup, SA Laursen, JB Chapalay, ... Mbio 11 (3), e00538-20, 2020 | 9 | 2020 |
Reflections on a sticky situation: how surface contact pulls the trigger for bacterial adhesion CL Kirkpatrick, PH Viollier Molecular microbiology 83 (1), 7-9, 2012 | 9 | 2012 |