Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma F Pistollato, S Abbadi, E Rampazzo, L Persano, A Della Puppa, ... Stem cells 28 (5), 851-862, 2010 | 375 | 2010 |
Glioblastoma cancer stem cells: role of the microenvironment and therapeutic targeting L Persano, E Rampazzo, G Basso, G Viola Biochemical pharmacology 85 (5), 612-622, 2013 | 204 | 2013 |
Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy S Indraccolo, S Minuzzo, M Masiero, I Pusceddu, L Persano, L Moserle, ... Cancer research 69 (4), 1314-1323, 2009 | 165 | 2009 |
BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression L Persano, F Pistollato, E Rampazzo, A Della Puppa, S Abbadi, ... Cell death & disease 3 (10), e412-e412, 2012 | 162 | 2012 |
Interaction of hypoxia-inducible factor-1α and Notch signaling regulates medulloblastoma precursor proliferation and fate F Pistollato, E Rampazzo, L Persano, S Abbadi, C Frasson, L Denaro, ... Stem Cells 28 (11), 1918-1929, 2010 | 141 | 2010 |
Wnt activation promotes neuronal differentiation of glioblastoma E Rampazzo, L Persano, F Pistollato, E Moro, C Frasson, P Porazzi, ... Cell death & disease 4 (2), e500-e500, 2013 | 130 | 2013 |
Anti-angiogenic gene therapy of cancer: current status and future prospects L Persano, M Crescenzi, S Indraccolo Molecular aspects of medicine 28 (1), 87-114, 2007 | 121 | 2007 |
The three‐layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implications L Persano, E Rampazzo, A Della Puppa, F Pistollato, G Basso The Scientific World Journal 11 (1), 1829-1841, 2011 | 110 | 2011 |
Notch3 signalling promotes tumour growth in colorectal cancer V Serafin, L Persano, L Moserle, G Esposito, M Ghisi, M Curtarello, ... The Journal of pathology 224 (4), 448-460, 2011 | 103 | 2011 |
Glycolytic phenotype and AMP kinase modify the pathologic response of tumor xenografts to VEGF neutralization G Nardo, E Favaro, M Curtarello, L Moserle, E Zulato, L Persano, E Rossi, ... Cancer research 71 (12), 4214-4225, 2011 | 81 | 2011 |
VEGF-targeted therapy stably modulates the glycolytic phenotype of tumor cells M Curtarello, E Zulato, G Nardo, S Valtorta, G Guzzo, E Rossi, G Esposito, ... Cancer research 75 (1), 120-133, 2015 | 71 | 2015 |
Notch3-mediated regulation of MKP-1 levels promotes survival of T acute lymphoblastic leukemia cells M Masiero, S Minuzzo, I Pusceddu, L Moserle, L Persano, V Agnusdei, ... Leukemia 25 (4), 588-598, 2011 | 71 | 2011 |
Hypoxia inducible factor-1α inactivation unveils a link between tumor cell metabolism and hypoxia-induced cell death E Favaro, G Nardo, L Persano, M Masiero, L Moserle, R Zamarchi, ... The American journal of pathology 173 (4), 1186-1201, 2008 | 68 | 2008 |
Hypoxia and succinate antagonize 2-deoxyglucose effects on glioblastoma F Pistollato, S Abbadi, E Rampazzo, G Viola, A Della Puppa, L Cavallini, ... Biochemical pharmacology 80 (10), 1517-1527, 2010 | 67 | 2010 |
Differential regulation of hypoxia-induced CXCR4 triggering during B-cell development and lymphomagenesis E Piovan, V Tosello, S Indraccolo, M Masiero, L Persano, G Esposito, ... Cancer research 67 (18), 8605-8614, 2007 | 55 | 2007 |
MGMT expression and promoter methylation status may depend on the site of surgical sample collection within glioblastoma: a possible pitfall in stratification of patients? A Della Puppa, L Persano, G Masi, E Rampazzo, A Sinigaglia, F Pistollato, ... Journal of neuro-oncology 106, 33-41, 2012 | 50 | 2012 |
Zebrafish reporter lines reveal in vivo signaling pathway activities involved in pancreatic cancer M Schiavone, E Rampazzo, A Casari, G Battilana, L Persano, E Moro, ... Disease models & mechanisms 7 (7), 883-894, 2014 | 49 | 2014 |
Interferon-α gene therapy by lentiviral vectors contrasts ovarian cancer growth through angiogenesis inhibition S Indraccolo, V Tisato, V Tosello, W Habeler, G Esposito, L Moserle, ... Human gene therapy 16 (8), 957-970, 2005 | 44 | 2005 |
TR-644 a novel potent tubulin binding agent induces impairment of endothelial cells function and inhibits angiogenesis E Porcu, G Viola, R Bortolozzi, L Persano, S Mitola, R Ronca, M Presta, ... Angiogenesis 16, 647-662, 2013 | 41 | 2013 |
AKR1C enzymes sustain therapy resistance in paediatric T-ALL R Bortolozzi, S Bresolin, E Rampazzo, M Paganin, F Maule, E Mariotto, ... British journal of cancer 118 (7), 985-994, 2018 | 39 | 2018 |