Physicochemical and formulation developability assessment for therapeutic peptide delivery—a primer A Bak, D Leung, SE Barrett, S Forster, EC Minnihan, AW Leithead, ... The AAPS journal 17, 144-155, 2015 | 99 | 2015 |
Development of a Convenient In Vitro Gel Diffusion Model for Predicting the In Vivo Performance of Subcutaneous Parenteral Formulations of Large and Small … DH Leung, Y Kapoor, C Alleyne, E Walsh, A Leithead, B Habulihaz, ... AAPS PharmSciTech 18, 2203-2213, 2017 | 42 | 2017 |
Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments CM Madsen, KI Feng, A Leithead, N Canfield, SA Jørgensen, A Müllertz, ... European Journal of Pharmaceutical Sciences 111, 311-319, 2018 | 34 | 2018 |
A retrospective analysis of preclinical and clinical pharmacokinetics from administration of long-acting aqueous suspensions AR Johnson, JE Ballard, A Leithead, C Miller, F Faassen, X Zang, ... Pharmaceutical Research 40 (7), 1641-1656, 2023 | 6 | 2023 |
Cerastecins inhibit membrane lipooligosaccharide transport in drug-resistant Acinetobacter baumannii H Wang, A Ishchenko, J Skudlarek, P Shen, L Dzhekieva, RE Painter, ... Nature Microbiology, 1-12, 2024 | 2 | 2024 |
Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration S Dong, Z Zhao, H Tang, G Li, J Pan, X Gu, J Jiang, L Xiao, G Scapin, ... Journal of Medicinal Chemistry 67 (5), 3400-3418, 2024 | 1 | 2024 |
Discovery of sulfone containing metallo-β-lactamase inhibitors with reduced bacterial cell efflux and histamine release issues F Bennett, Y Huang, S Dong, J Jiang, D Hunter, Z Zhao, X Gu, JD Scott, ... Bioorganic & Medicinal Chemistry Letters 114, 129989, 2024 | | 2024 |
Evaluation of a non-nucleoside inhibitor of the RSV RNA-dependent RNA polymerase in translatable animal models MP Citron, X Zang, A Leithead, S Meng, WA Rose II, E Murray, J Fontenot, ... Journal of Infection 89 (6), 106325, 2024 | | 2024 |
Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii: From Screening Impurity to In Vivo Efficacy JW Skudlarek, AJ Cooke, HJ Mitchell, K Babaoglu, AW Shaw, L Tong, ... Journal of Medicinal Chemistry 67 (17), 15620-15675, 2024 | | 2024 |
Discovery of Broad-Spectrum Herpes Antiviral Oxazolidinone Amide Derivatives and Their Structure–Activity Relationships MA Plotkin, M Labroli, J Schubert, A Shaw, KAS Schlegel, R Berger, ... ACS Medicinal Chemistry Letters 15 (8), 1232-1241, 2024 | | 2024 |
Discovery of Sulfone Containing Metallo-B-Lactamase Inhibitors with Reduced Bacterial Cell Efflux and Histamine Release Issues F Bennett, Y Huang, S Dong, J Jiang, Z Zhao, X Gu, JD Scott, H Tang, ... | | |