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Andrew Leithead
Andrew Leithead
Senior Scientist, Merck & Co., Inc.
在 merck.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Physicochemical and formulation developability assessment for therapeutic peptide delivery—a primer
A Bak, D Leung, SE Barrett, S Forster, EC Minnihan, AW Leithead, ...
The AAPS journal 17, 144-155, 2015
992015
Development of a Convenient In Vitro Gel Diffusion Model for Predicting the In Vivo Performance of Subcutaneous Parenteral Formulations of Large and Small …
DH Leung, Y Kapoor, C Alleyne, E Walsh, A Leithead, B Habulihaz, ...
AAPS PharmSciTech 18, 2203-2213, 2017
422017
Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments
CM Madsen, KI Feng, A Leithead, N Canfield, SA Jørgensen, A Müllertz, ...
European Journal of Pharmaceutical Sciences 111, 311-319, 2018
342018
A retrospective analysis of preclinical and clinical pharmacokinetics from administration of long-acting aqueous suspensions
AR Johnson, JE Ballard, A Leithead, C Miller, F Faassen, X Zang, ...
Pharmaceutical Research 40 (7), 1641-1656, 2023
62023
Cerastecins inhibit membrane lipooligosaccharide transport in drug-resistant Acinetobacter baumannii
H Wang, A Ishchenko, J Skudlarek, P Shen, L Dzhekieva, RE Painter, ...
Nature Microbiology, 1-12, 2024
22024
Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration
S Dong, Z Zhao, H Tang, G Li, J Pan, X Gu, J Jiang, L Xiao, G Scapin, ...
Journal of Medicinal Chemistry 67 (5), 3400-3418, 2024
12024
Discovery of sulfone containing metallo-β-lactamase inhibitors with reduced bacterial cell efflux and histamine release issues
F Bennett, Y Huang, S Dong, J Jiang, D Hunter, Z Zhao, X Gu, JD Scott, ...
Bioorganic & Medicinal Chemistry Letters 114, 129989, 2024
2024
Evaluation of a non-nucleoside inhibitor of the RSV RNA-dependent RNA polymerase in translatable animal models
MP Citron, X Zang, A Leithead, S Meng, WA Rose II, E Murray, J Fontenot, ...
Journal of Infection 89 (6), 106325, 2024
2024
Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii: From Screening Impurity to In Vivo Efficacy
JW Skudlarek, AJ Cooke, HJ Mitchell, K Babaoglu, AW Shaw, L Tong, ...
Journal of Medicinal Chemistry 67 (17), 15620-15675, 2024
2024
Discovery of Broad-Spectrum Herpes Antiviral Oxazolidinone Amide Derivatives and Their Structure–Activity Relationships
MA Plotkin, M Labroli, J Schubert, A Shaw, KAS Schlegel, R Berger, ...
ACS Medicinal Chemistry Letters 15 (8), 1232-1241, 2024
2024
Discovery of Sulfone Containing Metallo-B-Lactamase Inhibitors with Reduced Bacterial Cell Efflux and Histamine Release Issues
F Bennett, Y Huang, S Dong, J Jiang, Z Zhao, X Gu, JD Scott, H Tang, ...
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