Drug repurposing and human parasitic protozoan diseases KT Andrews, G Fisher, TS Skinner-Adams International Journal for Parasitology: Drugs and Drug Resistance 4 (2), 95-111, 2014 | 441 | 2014 |
Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum—The η-carbonic anhydrases S Del Prete, D Vullo, GM Fisher, KT Andrews, SA Poulsen, C Capasso, ... Bioorganic & Medicinal Chemistry Letters 24 (18), 4389-4396, 2014 | 355 | 2014 |
Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules K Trenholme, L Marek, S Duffy, G Pradel, G Fisher, FK Hansen, ... Antimicrobial agents and chemotherapy 58 (7), 3666-3678, 2014 | 74 | 2014 |
Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum D Vullo, S Del Prete, GM Fisher, KT Andrews, SA Poulsen, C Capasso, ... Bioorganic & Medicinal Chemistry 23 (3), 526-531, 2015 | 68 | 2015 |
Synthesis and antimalarial evaluation of novel benzopyrano[4,3-b]benzopyran derivatives R Devakaram, DSC Black, KT Andrews, GM Fisher, RA Davis, N Kumar Bioorganic & medicinal chemistry 19 (17), 5199-5206, 2011 | 47 | 2011 |
Antimalarial activity of compounds comprising a primary benzene sulfonamide fragment KT Andrews, GM Fisher, SDM Sumanadasa, T Skinner-Adams, J Moeker, ... Bioorganic & medicinal chemistry letters 23 (22), 6114-6117, 2013 | 43 | 2013 |
Defining the targets of antiparasitic compounds TS Skinner-Adams, SDM Sumanadasa, GM Fisher, RA Davis, DL Doolan, ... Drug discovery today 21 (5), 725-739, 2016 | 37 | 2016 |
One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites D Diedrich, K Stenzel, E Hesping, Y Antonova-Koch, T Gebru, S Duffy, ... European journal of medicinal chemistry 158, 801-813, 2018 | 35 | 2018 |
Assessing the anthelmintic activity of pyrazole-5-carboxamide derivatives against Haemonchus contortus Y Jiao, S Preston, H Song, A Jabbar, Y Liu, J Baell, A Hofmann, ... Parasites & vectors 10, 1-7, 2017 | 28 | 2017 |
Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain S Preston, PK Korhonen, L Mouchiroud, M Cornaglia, SL McGee, ... The FASEB Journal 31 (10), 4515-4532, 2017 | 27 | 2017 |
Synthesis and evaluation of antimalarial properties of novel 4‐aminoquinoline hybrid compounds GM Fisher, RP Tanpure, A Douchez, KT Andrews, SA Poulsen Chemical biology & drug design 84 (4), 462-472, 2014 | 27 | 2014 |
Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone TS Skinner-Adams, GM Fisher, AG Riches, OE Hutt, KE Jarvis, T Wilson, ... Communications biology 2 (1), 166, 2019 | 26 | 2019 |
Investigating the antiplasmodial activity of primary sulfonamide compounds identified in open source malaria data GM Fisher, S Bua, S Del Prete, MSJ Arnold, C Capasso, CT Supuran, ... International Journal for Parasitology: Drugs and Drug Resistance 7 (1), 61-70, 2017 | 19 | 2017 |
Adaptation of the [3H]Hypoxanthine Uptake Assay for In Vitro-Cultured Plasmodium knowlesi Malaria Parasites MSJ Arnold, JA Engel, MJ Chua, GM Fisher, TS Skinner-Adams, ... Antimicrobial Agents and Chemotherapy 60 (7), 4361-4363, 2016 | 18 | 2016 |
Antiplasmodial activity of the natural product compounds alstonine and himbeline MSJ Arnold, JR Macdonald, RJ Quinn, TS Skinner-Adams, KT Andrews, ... International Journal for Parasitology: Drugs and Drug Resistance 16, 17-22, 2021 | 11 | 2021 |
QSAR Classification models for prediction of hydroxamate histone deacetylase inhibitor activity against malaria parasites E Hesping, MJ Chua, M Pflieger, Y Qian, L Dong, P Bachu, L Liu, T Kurz, ... ACS Infectious Diseases 8 (1), 106-117, 2022 | 6 | 2022 |
The key glycolytic enzyme phosphofructokinase is involved in resistance to antiplasmodial glycosides GM Fisher, SA Cobbold, A Jezewski, EF Carpenter, M Arnold, AN Cowell, ... MBio 11 (6), 10.1128/mbio. 02842-20, 2020 | 5 | 2020 |
An ELISA method to assess HDAC inhibitor-induced alterations to P. falciparum histone lysine acetylation E Hesping, TS Skinner-Adams, GM Fisher, T Kurz, KT Andrews International Journal for Parasitology: Drugs and Drug Resistance 14, 249-256, 2020 | 5 | 2020 |
Histone deacetylase inhibitor AR-42 and achiral analogues kill malaria parasites in vitro and in mice MJ Chua, J Tng, E Hesping, GM Fisher, CD Goodman, T Skinner-Adams, ... International Journal for Parasitology: Drugs and Drug Resistance 17, 118-127, 2021 | 3 | 2021 |
Isolation and In Vitro and In Vivo Activity of Secondary Metabolites from Clerodendrum polycephalum Baker against Plasmodium Malaria Parasites R Tamuli, T Nguyen, JR Macdonald, GK Pierens, GM Fisher, KT Andrews, ... Journal of Natural Products 86 (12), 2661-2671, 2023 | 2 | 2023 |