Myosin light chain kinase is central to smooth muscle contraction and required for gastrointestinal motility in mice WQ He, YJ Peng, WC Zhang, N Lv, J Tang, C Chen, CH Zhang, S Gao, ... Gastroenterology 135 (2), 610-620. e2, 2008 | 210 | 2008 |
Myosin phosphatase target subunit 1 (MYPT1) regulates the contraction and relaxation of vascular smooth muscle and maintains blood pressure YN Qiao, WQ He, CP Chen, CH Zhang, W Zhao, P Wang, L Zhang, YZ Wu, ... Journal of Biological Chemistry 289 (32), 22512-22523, 2014 | 125 | 2014 |
Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum YJ Peng, WQ He, J Tang, T Tao, C Chen, YQ Gao, WC Zhang, XY He, ... Journal of Biological Chemistry 285 (32), 24834-24844, 2010 | 90 | 2010 |
MiR-23a inhibits myogenic differentiation through down regulation of fast myosin heavy chain isoforms L Wang, X Chen, Y Zheng, F Li, Z Lu, C Chen, J Liu, Y Wang, Y Peng, ... Experimental cell research 318 (18), 2324-2334, 2012 | 89 | 2012 |
Myosin light chain kinase is necessary for tonic airway smooth muscle contraction WC Zhang, YJ Peng, GS Zhang, WQ He, YN Qiao, YY Dong, YQ Gao, ... Journal of Biological Chemistry 285 (8), 5522-5531, 2010 | 88 | 2010 |
Myosin light chain kinase (MLCK) regulates cell migration in a myosin regulatory light chain phosphorylation-independent mechanism C Chen, T Tao, C Wen, WQ He, YN Qiao, YQ Gao, X Chen, P Wang, ... Journal of Biological Chemistry 289 (41), 28478-28488, 2014 | 80 | 2014 |
Altered contractile phenotypes of intestinal smooth muscle in mice deficient in myosin phosphatase target subunit 1 WQ He, YN Qiao, YJ Peng, JM Zha, CH Zhang, C Chen, CP Chen, ... Gastroenterology 144 (7), 1456-1465. e5, 2013 | 77 | 2013 |
Role of myosin light chain kinase in regulation of basal blood pressure and maintenance of salt-induced hypertension WQ He, YN Qiao, CH Zhang, YJ Peng, C Chen, P Wang, YQ Gao, C Chen, ... American Journal of Physiology-Heart and Circulatory Physiology 301 (2 …, 2011 | 68 | 2011 |
Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer Y Peng, M Li, BD Clarkson, M Pehar, PJ Lao, AT Hillmer, TE Barnhart, ... Journal of Neuroscience 34 (20), 6772-6789, 2014 | 62 | 2014 |
Hypothalamic mTORC2 is essential for metabolic health and longevity K Chellappa, JA Brinkman, S Mukherjee, M Morrison, MI Alotaibi, ... Aging Cell 18 (5), e13014, 2019 | 60 | 2019 |
Increased transport of acetyl‐CoA into the endoplasmic reticulum causes a progeria‐like phenotype Y Peng, SL Shapiro, VC Banduseela, IA Dieterich, KJ Hewitt, EH Bresnick, ... Aging cell 17 (5), e12820, 2018 | 46 | 2018 |
Acetyl-CoA flux regulates the proteome and acetyl-proteome to maintain intracellular metabolic crosstalk IA Dieterich, AJ Lawton, Y Peng, Q Yu, TW Rhoads, KA Overmyer, Y Cui, ... Nature Communications 10 (1), 3929, 2019 | 40 | 2019 |
Improved proteostasis in the secretory pathway rescues Alzheimer’s disease in the mouse Y Peng, MJ Kim, R Hullinger, KJ O’Riordan, C Burger, M Pehar, L Puglielli Brain 139 (3), 937-952, 2016 | 39 | 2016 |
The molecular basis of the genesis of basal tone in internal anal sphincter CH Zhang, P Wang, DH Liu, CP Chen, W Zhao, X Chen, C Chen, WQ He, ... Nature communications 7 (1), 11358, 2016 | 38 | 2016 |
Microfilament binding properties of N-terminal extension of long isoform of smooth muscle light chain kinase. ZMS Yang CX, Chen HQ, Chen C, Yu WP, Zhang WC, Peng YJ, He WQ, Wei DM, Gao X cell research 16 (4), 367-376, 2006 | 32* | 2006 |
Nϵ-lysine acetylation in the lumen of the endoplasmic reticulum: A way to regulate autophagy and maintain protein homeostasis in the secretory pathway Y Peng, L Puglielli Autophagy 12 (6), 1051-1052, 2016 | 30 | 2016 |
Golgi-resident TRIO regulates membrane trafficking during neurite outgrowth T Tao, J Sun, Y Peng, Y Li, P Wang, X Chen, W Zhao, YY Zheng, L Wei, ... Journal of Biological Chemistry 294 (28), 10954-10968, 2019 | 29 | 2019 |
Mass spectrometry imaging of N-glycans from formalin-fixed paraffin-embedded tissue sections using a novel subatmospheric pressure ionization source Y Shi, Z Li, MA Felder, Q Yu, X Shi, Y Peng, Q Cao, B Wang, L Puglielli, ... Analytical chemistry 91 (20), 12942-12947, 2019 | 25 | 2019 |
Deletion of myosin light chain kinase in endothelial cells has a minor effect on the lipopolysaccharide‐induced increase in microvascular endothelium permeability in mice Y Yu, N Lv, Z Lu, YY Zheng, WC Zhang, C Chen, YJ Peng, WQ He, ... The FEBS Journal 279 (8), 1485-1494, 2012 | 22 | 2012 |
Distinct functions of Trio GEF domains in axon outgrowth of cerebellar granule neurons T Tao, J Sun, Y Peng, P Wang, X Chen, W Zhao, Y Li, L Wei, W Wang, ... Journal of genetics and genomics 46 (2), 87-96, 2019 | 19 | 2019 |