SARS-CoV-2 infection of airway cells causes intense viral and cell shedding, two spreading mechanisms affected by IL-13 CB Morrison, CE Edwards, KM Shaffer, KC Araba, JA Wykoff, DR Williams, ... Proceedings of the National Academy of Sciences 119 (16), e2119680119, 2022 | 76 | 2022 |
Treatment of cystic fibrosis airway cells with CFTR modulators reverses aberrant mucus properties via hydration CB Morrison, KM Shaffer, KC Araba, MR Markovetz, JA Wykoff, ... European Respiratory Journal 59 (2), 2022 | 47 | 2022 |
Genomewide CRISPR knockout screen identified PLAC8 as an essential factor for SADS-CoVs infection LV Tse, RM Meganck, KC Araba, BL Yount, KM Shaffer, YJ Hou, JE Munt, ... Proceedings of the National Academy of Sciences 119 (18), e2118126119, 2022 | 21 | 2022 |
Mucins and CFTR: their close relationship K Okuda, KM Shaffer, C Ehre International journal of molecular sciences 23 (18), 10232, 2022 | 16 | 2022 |
Rapid viscoelastic characterization of airway mucus using a benchtop rheometer JA Wykoff, KM Shaffer, KC Araba, MR Markovetz, J Patarin, ... JoVE (Journal of Visualized Experiments), e63876, 2022 | 4 | 2022 |
638 Intestinal complications in cystic fibrosis: insights from F508del-Cftr mice on mucin dynamics and altered cellular functions H Dodson, K Araba, E Minor, K Shaffer, R Gilmore, C Morrison, H Dang, ... Journal of Cystic Fibrosis 23, S353, 2024 | | 2024 |
SARS-CoV-2 variant of concern fitness and adaptation in primary human airway epithelia RM Meganck, CE Edwards, ML Mallory, RE Lee, H Dang, AB Bailey, ... Cell Reports 43 (4), 2024 | | 2024 |
534 Mucus adhesion and inflammation causes bowel obstruction in cystic fibrosis mice ileum A Pitcairn, K Araba, A Karwande, J Wykoff, K Shaffer, R Gilmore, ... Journal of Cystic Fibrosis 22, S282-S283, 2023 | | 2023 |
18 CFTR modulators increase viral mobility in healthy and cystic fibrosis airway epithelial cells J Wykoff, K Shaffer, A Pitcairn, E Worthington, R Tarran, R Pickles, C Ehre Journal of Cystic Fibrosis 22, S11, 2023 | | 2023 |
388 Rapid viscoelastic characterization of airway mucus using a benchtop rheometer J Wykoff, K Shaffer, K Araba, M Markovetz, J Patarin, S Donaldson, ... Journal of Cystic Fibrosis 21, S227, 2022 | | 2022 |
498 Cystic fibrosis transmembrane conductance regulator modulator therapy increases viral mobility in primary cystic fibrosis airway cultures infected with respiratory … K Shaffer, J Wykoff, K Araba, E Worthington, R Tarran, R Pickles, C Ehre Journal of Cystic Fibrosis 21, S281-S282, 2022 | | 2022 |
215: Mucus hyperconcentration initiates bowel obstruction in the distal ileum of CF mice K Araba, P Santhanam, K Shaffer, C Morrison, R Gilmore, C Ehre Journal of Cystic Fibrosis 20, S105, 2021 | | 2021 |
179: Modulator therapy reverses aberrant mucus properties in vitro via hydration K Shaffer, C Morrison, K Araba, M Markovetz, N Quinney, L Morton, D Hill, ... Journal of Cystic Fibrosis 20, S88-S89, 2021 | | 2021 |