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Kendall M Shaffer
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SARS-CoV-2 infection of airway cells causes intense viral and cell shedding, two spreading mechanisms affected by IL-13
CB Morrison, CE Edwards, KM Shaffer, KC Araba, JA Wykoff, DR Williams, ...
Proceedings of the National Academy of Sciences 119 (16), e2119680119, 2022
762022
Treatment of cystic fibrosis airway cells with CFTR modulators reverses aberrant mucus properties via hydration
CB Morrison, KM Shaffer, KC Araba, MR Markovetz, JA Wykoff, ...
European Respiratory Journal 59 (2), 2022
472022
Genomewide CRISPR knockout screen identified PLAC8 as an essential factor for SADS-CoVs infection
LV Tse, RM Meganck, KC Araba, BL Yount, KM Shaffer, YJ Hou, JE Munt, ...
Proceedings of the National Academy of Sciences 119 (18), e2118126119, 2022
212022
Mucins and CFTR: their close relationship
K Okuda, KM Shaffer, C Ehre
International journal of molecular sciences 23 (18), 10232, 2022
162022
Rapid viscoelastic characterization of airway mucus using a benchtop rheometer
JA Wykoff, KM Shaffer, KC Araba, MR Markovetz, J Patarin, ...
JoVE (Journal of Visualized Experiments), e63876, 2022
42022
638 Intestinal complications in cystic fibrosis: insights from F508del-Cftr mice on mucin dynamics and altered cellular functions
H Dodson, K Araba, E Minor, K Shaffer, R Gilmore, C Morrison, H Dang, ...
Journal of Cystic Fibrosis 23, S353, 2024
2024
SARS-CoV-2 variant of concern fitness and adaptation in primary human airway epithelia
RM Meganck, CE Edwards, ML Mallory, RE Lee, H Dang, AB Bailey, ...
Cell Reports 43 (4), 2024
2024
534 Mucus adhesion and inflammation causes bowel obstruction in cystic fibrosis mice ileum
A Pitcairn, K Araba, A Karwande, J Wykoff, K Shaffer, R Gilmore, ...
Journal of Cystic Fibrosis 22, S282-S283, 2023
2023
18 CFTR modulators increase viral mobility in healthy and cystic fibrosis airway epithelial cells
J Wykoff, K Shaffer, A Pitcairn, E Worthington, R Tarran, R Pickles, C Ehre
Journal of Cystic Fibrosis 22, S11, 2023
2023
388 Rapid viscoelastic characterization of airway mucus using a benchtop rheometer
J Wykoff, K Shaffer, K Araba, M Markovetz, J Patarin, S Donaldson, ...
Journal of Cystic Fibrosis 21, S227, 2022
2022
498 Cystic fibrosis transmembrane conductance regulator modulator therapy increases viral mobility in primary cystic fibrosis airway cultures infected with respiratory …
K Shaffer, J Wykoff, K Araba, E Worthington, R Tarran, R Pickles, C Ehre
Journal of Cystic Fibrosis 21, S281-S282, 2022
2022
215: Mucus hyperconcentration initiates bowel obstruction in the distal ileum of CF mice
K Araba, P Santhanam, K Shaffer, C Morrison, R Gilmore, C Ehre
Journal of Cystic Fibrosis 20, S105, 2021
2021
179: Modulator therapy reverses aberrant mucus properties in vitro via hydration
K Shaffer, C Morrison, K Araba, M Markovetz, N Quinney, L Morton, D Hill, ...
Journal of Cystic Fibrosis 20, S88-S89, 2021
2021
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