GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3 Y Zhao, F Chen, W Wu, M Sun, AJ Bilotta, S Yao, Y Xiao, X Huang, ... Mucosal immunology 11 (3), 752-762, 2018 | 406 | 2018 |
Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: IκBα degradation, induction of nitric oxide synthase, induction of … T Eaves-Pyles, K Murthy, L Liaudet, L Virág, G Ross, FG Soriano, ... The Journal of Immunology 166 (2), 1248-1260, 2001 | 395 | 2001 |
Salmonella flagellin-dependent proinflammatory responses are localized to the conserved amino and carboxyl regions of the protein TD Eaves-Pyles, HR Wong, K Odoms, RB Pyles The Journal of Immunology 167 (12), 7009-7016, 2001 | 237 | 2001 |
Escherichia coli isolated from a Crohn's disease patient adheres, invades, and induces inflammatory responses in polarized intestinal epithelial cells T Eaves-Pyles, CA Allen, J Taormina, A Swidsinski, CB Tutt, GE Jezek, ... International Journal of Medical Microbiology 298 (5-6), 397-409, 2008 | 214 | 2008 |
Critical role for serum opsonins and complement receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by human dendritic cells … A Ben Nasr, J Haithcoat, JE Masterson, JS Gunn, T Eaves-Pyles, ... Journal of leukocyte biology 80 (4), 774-786, 2006 | 187 | 2006 |
Commensal bacteria modulate innate immune responses of vaginal epithelial cell multilayer cultures WA Rose, CL McGowin, RA Spagnuolo, TD Eaves-Pyles, VL Popov, ... PloS one 7 (3), e32728, 2012 | 160 | 2012 |
Bacterial induction of inducible nitric oxide synthase in cultured human intestinal epithelial cells AL Salzman, T Eaves–Pyles, SC Linn, AG Denenberg, C Szabó Gastroenterology 114 (1), 93-102, 1998 | 116 | 1998 |
Outer Membrane Protein A of Escherichia coli O157:H7 Stimulates Dendritic Cell Activation AG Torres, Y Li, CB Tutt, L Xin, T Eaves-Pyles, L Soong Infection and immunity 74 (5), 2676-2685, 2006 | 89 | 2006 |
Granulocyte macrophage colony-stimulating factor improves survival in two models of gut-derived sepsis by improving gut barrier function and modulating bacterial clearance R Gennari, JW Alexander, L Gianotti, T Eaves-Pyles, S Hartmann Annals of surgery 220 (1), 68-76, 1994 | 81 | 1994 |
Bacterial invasion is not required for activation of NF-κB in enterocytes T Eaves-Pyles, C Szabó, AL Salzman Infection and immunity 67 (2), 800-804, 1999 | 76 | 1999 |
Heat shock inhibits phosphorylation of I-κBα TP Shanley, MA Ryan, T Eaves-Pyles, HR Wong Shock 14 (4), 447-450, 2000 | 75 | 2000 |
Effect of different combinations of dietary additives on bacterial translocation and survival in gut‐derived sepsis R Gennari, JW Alexander, T Eaves‐Pyles Journal of Parenteral and Enteral Nutrition 19 (4), 319-325, 1995 | 73 | 1995 |
Role of Primary Human Alveolar Epithelial Cells in Host Defense against Francisella tularensis Infection M Gentry, J Taormina, RB Pyles, L Yeager, M Kirtley, VL Popov, G Klimpel, ... Infection and immunity 75 (8), 3969-3978, 2007 | 71 | 2007 |
Heat shock inhibits activation of NF-κB in the absence of heat shock factor-1 V Malhotra, T Eaves-Pyles, K Odoms, G Quaid, TP Shanley, HR Wong Biochemical and biophysical research communications 291 (3), 453-457, 2002 | 66 | 2002 |
Levofloxacin rescues mice from lethal intra-nasal infections with virulent Francisella tularensis and induces immunity and production of protective antibody GR Klimpel, T Eaves-Pyles, ST Moen, J Taormina, JW Peterson, ... Vaccine 26 (52), 6874-6882, 2008 | 63 | 2008 |
Cultivated vaginal microbiomes alter HIV-1 infection and antiretroviral efficacy in colonized epithelial multilayer cultures RB Pyles, KL Vincent, MM Baum, B Elsom, AL Miller, C Maxwell, ... PloS one 9 (3), e93419, 2014 | 55 | 2014 |
Rapid and prolonged impairment of gut barrier function after thermal injury in mice T Eaves-Pyles, JW Alexander Shock 9 (2), 95-100, 1998 | 45 | 1998 |
Protection afforded by fluoroquinolones in animal models of respiratory infections with Bacillus anthracis, Yersinia pestis, and Francisella tularensis JW Peterson, ST Moen, D Healy, JE Pawlik, J Taormina, J Hardcastle, ... The open microbiology journal 4, 34, 2010 | 43 | 2010 |
Toll-Like Receptor 3 Agonist Protection against Experimental Francisella tularensis Respiratory Tract Infection RB Pyles, GE Jezek, TD Eaves-Pyles Infection and immunity 78 (4), 1700-1710, 2010 | 39 | 2010 |
IFN-γ decreases translocation and improves survival following transfusion and thermal injury R Gennari, JW Alexander, T Eaves-Pyles Journal of Surgical Research 56 (6), 530-536, 1994 | 36 | 1994 |