| The flavanol (−)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP … F Meng, A Abedini, A Plesner, CB Verchere, DP Raleigh Biochemistry 49 (37), 8127-8133, 2010 | 310 | 2010 |
| Islet amyloid polypeptide: structure, function, and pathophysiology R Akter, P Cao, H Noor, Z Ridgway, LH Tu, H Wang, AG Wong, X Zhang, ... Journal of diabetes research 2016 (1), 2798269, 2016 | 253 | 2016 |
| Mechanisms of islet amyloidosis toxicity in type 2 diabetes A Abedini, AM Schmidt FEBS letters 587 (8), 1119-1127, 2013 | 225 | 2013 |
| A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides A Abedini, DP Raleigh Protein Engineering, Design & Selection 22 (8), 453-459, 2009 | 219 | 2009 |
| A role for helical intermediates in amyloid formation by natively unfolded polypeptides? A Abedini, DP Raleigh Physical biology 6 (1), 015005, 2009 | 211 | 2009 |
| Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts KJ Potter, A Abedini, P Marek, AM Klimek, S Butterworth, M Driscoll, ... Proceedings of the National Academy of Sciences 107 (9), 4305-4310, 2010 | 204 | 2010 |
| Islet amyloid: from fundamental biophysics to mechanisms of cytotoxicity P Cao, P Marek, H Noor, V Patsalo, LH Tu, H Wang, A Abedini, ... FEBS letters 587 (8), 1106-1118, 2013 | 199 | 2013 |
| A single-point mutation converts the highly amyloidogenic human islet amyloid polypeptide into a potent fibrillization inhibitor A Abedini, F Meng, DP Raleigh Journal of the American Chemical Society 129 (37), 11300-11301, 2007 | 191 | 2007 |
| The role of His-18 in amyloid formation by human islet amyloid polypeptide A Abedini, DP Raleigh Biochemistry 44 (49), 16284-16291, 2005 | 190 | 2005 |
| Aromatic interactions are not required for amyloid fibril formation by islet amyloid polypeptide but do influence the rate of fibril formation and fibril morphology P Marek, A Abedini, BB Song, M Kanungo, ME Johnson, R Gupta, ... Biochemistry 46 (11), 3255-3261, 2007 | 167 | 2007 |
| Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics A Abedini, A Plesner, P Cao, Z Ridgway, J Zhang, LH Tu, CT Middleton, ... Elife 5, e12977, 2016 | 166 | 2016 |
| Incorporation of pseudoproline derivatives allows the facile synthesis of human IAPP, a highly amyloidogenic and aggregation-prone polypeptide A Abedini, DP Raleigh Organic letters 7 (4), 693-696, 2005 | 161 | 2005 |
| Islet amyloid polypeptide toxicity and membrane interactions P Cao, A Abedini, H Wang, LH Tu, X Zhang, AM Schmidt, DP Raleigh Proceedings of the National Academy of Sciences 110 (48), 19279-19284, 2013 | 160 | 2013 |
| Role of aromatic interactions in amyloid formation by peptides derived from human amylin SM Tracz, A Abedini, M Driscoll, DP Raleigh Biochemistry 43 (50), 15901-15908, 2004 | 146 | 2004 |
| Aggregation of islet amyloid polypeptide: from physical chemistry to cell biology P Cao, A Abedini, DP Raleigh Current opinion in structural biology 23 (1), 82-89, 2013 | 130 | 2013 |
| Destabilization of human IAPP amyloid fibrils by proline mutations outside of the putative amyloidogenic domain: is there a critical amyloidogenic domain in human IAPP? A Abedini, DP Raleigh Journal of molecular biology 355 (2), 274-281, 2006 | 126 | 2006 |
| Rational design of potent domain antibody inhibitors of amyloid fibril assembly ARA Ladiwala, M Bhattacharya, JM Perchiacca, P Cao, DP Raleigh, ... Proceedings of the National Academy of Sciences 109 (49), 19965-19970, 2012 | 109 | 2012 |
| The ability of rodent islet amyloid polypeptide to inhibit amyloid formation by human islet amyloid polypeptide has important implications for the mechanism of amyloid … P Cao, F Meng, A Abedini, DP Raleigh Biochemistry 49 (5), 872-881, 2010 | 96 | 2010 |
| Recovery and purification of highly aggregation-prone disulfide-containing peptides: application to islet amyloid polypeptide A Abedini, G Singh, DP Raleigh Analytical biochemistry 351 (2), 181-186, 2006 | 93 | 2006 |
| Sensitivity of amyloid formation by human islet amyloid polypeptide to mutations at residue 20 P Cao, LH Tu, A Abedini, O Levsh, R Akter, V Patsalo, AM Schmidt, ... Journal of molecular biology 421 (2-3), 282-295, 2012 | 92 | 2012 |
