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Emily G. Knox
Emily G. Knox
在 umail.ucc.ie 的电子邮件经过验证
标题
引用次数
引用次数
年份
The blood-brain barrier in aging and neurodegeneration
EG Knox, MR Aburto, G Clarke, JF Cryan, CM O’Driscoll
Molecular Psychiatry 27 (6), 2659-2673, 2022
2322022
Short chain fatty acids: microbial metabolites for gut-brain axis signalling
KJ O'Riordan, MK Collins, GM Moloney, EG Knox, MR Aburto, C Fülling, ...
Molecular and Cellular Endocrinology 546, 111572, 2022
1842022
A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system
JF Alterman, BMDC Godinho, MR Hassler, CM Ferguson, D Echeverria, ...
Nature biotechnology 37 (8), 884-894, 2019
1662019
Microbial-derived metabolites induce actin cytoskeletal rearrangement and protect blood-brain barrier function
EG Knox, MR Aburto, C Tessier, J Nagpal, G Clarke, CM O’Driscoll, ...
iscience 25 (12), 2022
282022
Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep
CM Ferguson, BMDC Godinho, JF Alterman, AH Coles, M Hassler, ...
JCI insight 6 (24), 2021
162021
Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington’s disease models
F Conroy, R Miller, JF Alterman, MR Hassler, D Echeverria, ...
Nature communications 13 (1), 5802, 2022
142022
PK-modifying anchors significantly alter clearance kinetics, tissue distribution, and efficacy of therapeutics siRNAs
BMDC Godinho, EG Knox, S Hildebrand, JW Gilbert, D Echeverria, ...
Molecular Therapy-Nucleic Acids 29, 116-132, 2022
142022
The gut microbiota is important for the maintenance of blood–cerebrospinal fluid barrier integrity
EG Knox, CMK Lynch, YS Lee, CM O'Driscoll, G Clarke, JF Cryan, ...
European Journal of Neuroscience 57 (2), 233-241, 2023
122023
2′-O-Methyl at 20-mer guide strand 3′ termini may negatively affect target silencing activity of fully chemically modified siRNA
SM Davis, J Sousa, L Vangjeli, MR Hassler, D Echeverria, E Knox, ...
Molecular Therapy-Nucleic Acids 21, 266-277, 2020
112020
Microbial-derived metabolites induce actin cytoskeletal rearrangement and protect blood-brain barrier function. iScience 25
EG Knox, MR Aburto, C Tessier, J Nagpal, G Clarke, CM O’Driscoll, ...
72022
The role of the gut microbiota in the function and integrity of brain barriers
EG Knox
University College Cork, 2023
2023
Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in vivo in CNS
F Conroy, R Miller, JF Alterman, MR Hassler, D Echeverria, ...
bioRxiv, 2022.06. 29.498088, 2022
2022
The gut microbiota is important for the maintenance of blood-cerebrospinal fluid barrier integrity.
YS Lee, M Rodriguez Aburto, E Knox, C Lynch, C O'Driscoll, G Clarke, ...
2022
Microbial metabolites and blood brain barrier physiology/integrity: focus on mechanisms
E Knox, MR Aburto, G Clarke, JF Cryan, C O'Driscoll
Neuroscience Applied 1, 100023, 2022
2022
Chemical Engineering of Therapeutic RNAs for Allele Specific Gene Silencing In Vivo
F Conroy, J Alterman, B Godinho, E Sapp, D Echeverria, M Hassler, ...
MOLECULAR THERAPY 28 (4), 393-393, 2020
2020
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