关注
Sinto Sebastian Chirackal
Sinto Sebastian Chirackal
Research Scientist, Mayo Clinic
在 mayo.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The complexity of targeting EGFR signalling in cancer: from expression to turnover
S Sebastian, J Settleman, SJ Reshkin, A Azzariti, A Bellizzi, A Paradiso
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1766 (1), 120-139, 2006
3992006
p53 haploinsufficiency and functional abnormalities in multiple myeloma
PJ Teoh, TH Chung, S Sebastian, SN Choo, J Yan, SB Ng, R Fonseca, ...
Leukemia 28 (10), 2066-2074, 2014
972014
Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer
A Azzariti, G Bocci, L Porcelli, A Fioravanti, P Sini, GM Simone, ...
British journal of cancer 104 (5), 769-780, 2011
822011
Tumor-associated macrophages and extracellular matrix metalloproteinase inducer in prognosis of multiple myeloma
S Panchabhai, K Kelemen, G Ahmann, S Sebastian, J Mantei, R Fonseca
Leukemia 30 (4), 951-954, 2016
692016
Co‐expression of CD133+/CD44+ in human colon cancer and liver metastasis
A Bellizzi, S Sebastian, P Ceglia, M Centonze, R Divella, EF Manzillo, ...
Journal of cellular physiology 228 (2), 408-415, 2013
612013
Multiple myeloma cells’ capacity to decompose H2O2 determines lenalidomide sensitivity
S Sebastian, YX Zhu, E Braggio, CX Shi, SC Panchabhai, SA Van Wier, ...
Blood, The Journal of the American Society of Hematology 129 (8), 991-1007, 2017
522017
Evaluation of Revised International Staging System (R-ISS) for transplant-eligible multiple myeloma patients
V González-Calle, A Slack, N Keane, S Luft, KE Pearce, RP Ketterling, ...
Annals of hematology 97, 1453-1462, 2018
412018
Inactivation of the putative suppressor gene DOK1 by promoter hypermethylation in primary human cancers
A Saulnier, T Vaissière, J Yue, M Siouda, M Malfroy, R Accardi, ...
International journal of cancer 130 (11), 2484-2494, 2012
412012
PKM2 and other key regulators of Warburg effect positively correlate with CD147 (EMMPRIN) gene expression and predict survival in multiple myeloma
S Panchabhai, I Schlam, S Sebastian, R Fonseca
Leukemia 31 (4), 991-994, 2017
342017
PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation
PJ Teoh, C Bi, C Sintosebastian, LS Tay, R Fonseca, WJ Chng
Oncotarget 7 (38), 61806, 2016
302016
p53 as the main traffic controller of the cell signaling network
S Sebastian, A Azzariti, N Silvestris, L Porcelli, A Russo, A Paradiso
Front Biosci 15, 1172-1190, 2010
242010
Wip1 contributes to cell homeostasis maintained by the steady-state level of Wtp53
HK Park, J Panneerselvam, FD Dudimah, G Dong, S Sebastian, J Zhang, ...
Cell cycle 10 (15), 2574-2582, 2011
172011
Telomeres, telomerase and oral cancer
S Sebastian, L Grammatica, A Paradiso
International journal of oncology 27 (6), 1583-1596, 2005
172005
Validation of gefitinib effectiveness in a broad panel of head and neck squamous carcinoma cells
S Sebastian, A Azzariti, R Accardi, D Conti, B Pilato, R LaCalamita, ...
International journal of molecular medicine 21 (6), 809-817, 2008
112008
Prediction of immunomodulatory drugs (IMiDs) sensitivity in myeloma via determination of baseline anti-oxidative stress capacity
L Mountjoy, S Sebastian, T Jain, T Hilal, M Gonzalez-Velez, M Girardo, ...
Leukemia 34 (11), 3060-3063, 2020
102020
PARP Inhibition (OLAPARIB) Enhance Melphalan and Nutlin-3a Sensitivity in TP53 Positive Multiple Myeloma
S Sebastian, M Chesi, E Braggio, L Bergsagel, K Stewart, G Ahmann, ...
Blood 120 (21), 1846, 2012
32012
Results of a Flow Cytometry Assay Measuring Oxidative Stress Relief As a Predictor of Immunomodulatory Drugs (IMIDs) Sensitivity in Myeloma
L Mountjoy, S Chirackal, T Jain, M Girardo, J Larsen, R Fonseca
Blood 132, 4443, 2018
12018
Lenalidomide Inhibits Thioredoxin Reductase (TrxR) in Multiple Myeloma (MM) Cells but Direct Inhibition of Trxr and Thioredoxin (Trx) Can Bypass Requirement of Cereblon (CRBN)
SS Chirackal, E Braggio, YX Zhu, CX Shi, S Van Wier, G Ahmann, ...
Blood 128 (22), 4482, 2016
12016
Unraveling Antioxidative Metabolic Pathways in Multiple Myeloma: Augmenting IMiD Sensitivity through Intracellular Cysteine Biosynthesis Inhibition
SS Chirackal, T Hitosugi, G Ahmann, E Braggio, M Chesi, PL Bergsagel, ...
Blood 142, 3291, 2023
2023
Myeloma Cells Addicted to Glutamine for Biomass Production Are Sensitive to Lenalidomide
S Chirackal, E Braggio, R Atiqur, GJ Ahmann, YX Zhu, AK Stewart, ...
Blood 134, 4410, 2019
2019
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