The complexity of targeting EGFR signalling in cancer: from expression to turnover S Sebastian, J Settleman, SJ Reshkin, A Azzariti, A Bellizzi, A Paradiso Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1766 (1), 120-139, 2006 | 399 | 2006 |
p53 haploinsufficiency and functional abnormalities in multiple myeloma PJ Teoh, TH Chung, S Sebastian, SN Choo, J Yan, SB Ng, R Fonseca, ... Leukemia 28 (10), 2066-2074, 2014 | 97 | 2014 |
Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer A Azzariti, G Bocci, L Porcelli, A Fioravanti, P Sini, GM Simone, ... British journal of cancer 104 (5), 769-780, 2011 | 82 | 2011 |
Tumor-associated macrophages and extracellular matrix metalloproteinase inducer in prognosis of multiple myeloma S Panchabhai, K Kelemen, G Ahmann, S Sebastian, J Mantei, R Fonseca Leukemia 30 (4), 951-954, 2016 | 69 | 2016 |
Co‐expression of CD133+/CD44+ in human colon cancer and liver metastasis A Bellizzi, S Sebastian, P Ceglia, M Centonze, R Divella, EF Manzillo, ... Journal of cellular physiology 228 (2), 408-415, 2013 | 61 | 2013 |
Multiple myeloma cells’ capacity to decompose H2O2 determines lenalidomide sensitivity S Sebastian, YX Zhu, E Braggio, CX Shi, SC Panchabhai, SA Van Wier, ... Blood, The Journal of the American Society of Hematology 129 (8), 991-1007, 2017 | 52 | 2017 |
Evaluation of Revised International Staging System (R-ISS) for transplant-eligible multiple myeloma patients V González-Calle, A Slack, N Keane, S Luft, KE Pearce, RP Ketterling, ... Annals of hematology 97, 1453-1462, 2018 | 41 | 2018 |
Inactivation of the putative suppressor gene DOK1 by promoter hypermethylation in primary human cancers A Saulnier, T Vaissière, J Yue, M Siouda, M Malfroy, R Accardi, ... International journal of cancer 130 (11), 2484-2494, 2012 | 41 | 2012 |
PKM2 and other key regulators of Warburg effect positively correlate with CD147 (EMMPRIN) gene expression and predict survival in multiple myeloma S Panchabhai, I Schlam, S Sebastian, R Fonseca Leukemia 31 (4), 991-994, 2017 | 34 | 2017 |
PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation PJ Teoh, C Bi, C Sintosebastian, LS Tay, R Fonseca, WJ Chng Oncotarget 7 (38), 61806, 2016 | 30 | 2016 |
p53 as the main traffic controller of the cell signaling network S Sebastian, A Azzariti, N Silvestris, L Porcelli, A Russo, A Paradiso Front Biosci 15, 1172-1190, 2010 | 24 | 2010 |
Wip1 contributes to cell homeostasis maintained by the steady-state level of Wtp53 HK Park, J Panneerselvam, FD Dudimah, G Dong, S Sebastian, J Zhang, ... Cell cycle 10 (15), 2574-2582, 2011 | 17 | 2011 |
Telomeres, telomerase and oral cancer S Sebastian, L Grammatica, A Paradiso International journal of oncology 27 (6), 1583-1596, 2005 | 17 | 2005 |
Validation of gefitinib effectiveness in a broad panel of head and neck squamous carcinoma cells S Sebastian, A Azzariti, R Accardi, D Conti, B Pilato, R LaCalamita, ... International journal of molecular medicine 21 (6), 809-817, 2008 | 11 | 2008 |
Prediction of immunomodulatory drugs (IMiDs) sensitivity in myeloma via determination of baseline anti-oxidative stress capacity L Mountjoy, S Sebastian, T Jain, T Hilal, M Gonzalez-Velez, M Girardo, ... Leukemia 34 (11), 3060-3063, 2020 | 10 | 2020 |
PARP Inhibition (OLAPARIB) Enhance Melphalan and Nutlin-3a Sensitivity in TP53 Positive Multiple Myeloma S Sebastian, M Chesi, E Braggio, L Bergsagel, K Stewart, G Ahmann, ... Blood 120 (21), 1846, 2012 | 3 | 2012 |
Results of a Flow Cytometry Assay Measuring Oxidative Stress Relief As a Predictor of Immunomodulatory Drugs (IMIDs) Sensitivity in Myeloma L Mountjoy, S Chirackal, T Jain, M Girardo, J Larsen, R Fonseca Blood 132, 4443, 2018 | 1 | 2018 |
Lenalidomide Inhibits Thioredoxin Reductase (TrxR) in Multiple Myeloma (MM) Cells but Direct Inhibition of Trxr and Thioredoxin (Trx) Can Bypass Requirement of Cereblon (CRBN) SS Chirackal, E Braggio, YX Zhu, CX Shi, S Van Wier, G Ahmann, ... Blood 128 (22), 4482, 2016 | 1 | 2016 |
Unraveling Antioxidative Metabolic Pathways in Multiple Myeloma: Augmenting IMiD Sensitivity through Intracellular Cysteine Biosynthesis Inhibition SS Chirackal, T Hitosugi, G Ahmann, E Braggio, M Chesi, PL Bergsagel, ... Blood 142, 3291, 2023 | | 2023 |
Myeloma Cells Addicted to Glutamine for Biomass Production Are Sensitive to Lenalidomide S Chirackal, E Braggio, R Atiqur, GJ Ahmann, YX Zhu, AK Stewart, ... Blood 134, 4410, 2019 | | 2019 |