Nutrient-dependent mTORC1 association with the ULK1–Atg13–FIP200 complex required for autophagy N Hosokawa, T Hara, T Kaizuka, C Kishi, A Takamura, Y Miura, S Iemura, ... Molecular biology of the cell 20 (7), 1981-1991, 2009 | 2467 | 2009 |
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice M Komatsu, S Waguri, M Koike, Y Sou, T Ueno, T Hara, N Mizushima, ... Cell 131 (6), 1149-1163, 2007 | 2386 | 2007 |
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 M Komatsu, H Kurokawa, S Waguri, K Taguchi, A Kobayashi, Y Ichimura, ... Nature cell biology 12 (3), 213-223, 2010 | 2377 | 2010 |
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells T Hara, A Takamura, C Kishi, S Iemura, T Natsume, JL Guan, ... The Journal of cell biology 181 (3), 497-510, 2008 | 1117 | 2008 |
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate N Mizushima, A Kuma, Y Kobayashi, A Yamamoto, M Matsubae, T Takao, ... Journal of cell science 116 (9), 1679-1688, 2003 | 978 | 2003 |
Shugoshin collaborates with protein phosphatase 2A to protect cohesin TS Kitajima, T Sakuno, K Ishiguro, S Iemura, T Natsume, SA Kawashima, ... Nature 441 (7089), 46-52, 2006 | 725 | 2006 |
Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo S Iemura, TS Yamamoto, C Takagi, H Uchiyama, T Natsume, S Shimasaki, ... Proceedings of the National Academy of Sciences 95 (16), 9337-9342, 1998 | 568 | 1998 |
Atg101, a novel mammalian autophagy protein interacting with Atg13 N Hosokawa, T Sasaki, S Iemura, T Natsume, T Hara, N Mizushima Autophagy 5 (7), 973-979, 2009 | 567 | 2009 |
The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17 P Jiang, T Nishimura, Y Sakamaki, E Itakura, T Hatta, T Natsume, ... Molecular biology of the cell 25 (8), 1327-1337, 2014 | 527 | 2014 |
WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1 T Moriguchi, S Urushiyama, N Hisamoto, S Iemura, S Uchida, T Natsume, ... Journal of Biological Chemistry 280 (52), 42685-42693, 2005 | 527 | 2005 |
Skp2-mediated degradation of p27 regulates progression into mitosis K Nakayama, H Nagahama, YA Minamishima, S Miyake, N Ishida, ... Developmental cell 6 (5), 661-672, 2004 | 418 | 2004 |
Subtype-specific and ER lumenal environment-dependent regulation of inositol 1, 4, 5-trisphosphate receptor type 1 by ERp44 T Higo, M Hattori, T Nakamura, T Natsume, T Michikawa, K Mikoshiba Cell 120 (1), 85-98, 2005 | 403 | 2005 |
A novel protein‐conjugating system for Ufm1, a ubiquitin‐fold modifier M Komatsu, T Chiba, K Tatsumi, S Iemura, I Tanida, N Okazaki, T Ueno, ... The EMBO journal 23 (9), 1977-1986, 2004 | 397 | 2004 |
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1 S Nakada, I Tai, S Panier, A Al-Hakim, S Iemura, YC Juang, L O’Donnell, ... Nature 466 (7309), 941-946, 2010 | 389 | 2010 |
Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly T Kaizuka, T Hara, N Oshiro, U Kikkawa, K Yonezawa, K Takehana, ... Journal of Biological Chemistry 285 (26), 20109-20116, 2010 | 354 | 2010 |
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage K Yoshida, T Yamaguchi, T Natsume, D Kufe, Y Miki Nature cell biology 7 (3), 278-285, 2005 | 307 | 2005 |
A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes Y Hirano, KB Hendil, H Yashiroda, S Iemura, R Nagane, Y Hioki, ... Nature 437 (7063), 1381-1385, 2005 | 301 | 2005 |
A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes J Hamazaki, S Iemura, T Natsume, H Yashiroda, K Tanaka, S Murata The EMBO journal 25 (19), 4524-4536, 2006 | 296 | 2006 |
Intrinsically disordered protein TEX264 mediates ER-phagy H Chino, T Hatta, T Natsume, N Mizushima Molecular cell 74 (5), 909-921. e6, 2019 | 274 | 2019 |
Activity-dependent synaptogenesis: regulation by a CaM-kinase kinase/CaM-kinase I/βPIX signaling complex T Saneyoshi, G Wayman, D Fortin, M Davare, N Hoshi, N Nozaki, ... Neuron 57 (1), 94-107, 2008 | 262 | 2008 |