Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells S Žuklys, A Handel, S Zhanybekova, F Govani, M Keller, S Maio, ... Nature immunology 17 (10), 1206-1215, 2016 | 188 | 2016 |
Ageing compromises mouse thymus function and remodels epithelial cell differentiation J Baran-Gale, MD Morgan, S Maio, F Dhalla, I Calvo-Asensio, ... Elife 9, e56221, 2020 | 120 | 2020 |
Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells F Dhalla, J Baran‐Gale, S Maio, L Chappell, GA Holländer, CP Ponting The EMBO journal 39 (1), e101828, 2020 | 81 | 2020 |
From Murine to Human Nude/SCID: The Thymus, T‐Cell Development and the Missing Link R Romano, L Palamaro, A Fusco, L Iannace, S Maio, I Vigliano, ... Journal of Immunology Research 2012 (1), 467101, 2012 | 58 | 2012 |
Inborn errors of thymic stromal cell development and function AY Kreins, S Maio, F Dhalla Seminars in Immunopathology 43 (1), 85-100, 2021 | 22 | 2021 |
Comprehensively profiling the chromatin architecture of tissue restricted antigen expression in thymic epithelial cells over development AE Handel, N Shikama-Dorn, S Zhanybekova, S Maio, AN Graedel, ... Frontiers in immunology 9, 2120, 2018 | 19 | 2018 |
Keratinocyte growth factor impairs human thymic recovery from lymphopenia AJ Coles, L Azzopardi, O Kousin-Ezewu, HK Mullay, SAJ Thompson, ... JCI insight 4 (12), 2019 | 18 | 2019 |
FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency IA Rota, AE Handel, S Maio, F Klein, F Dhalla, ME Deadman, S Cheuk, ... Science Advances 7 (49), eabj9247, 2021 | 13 | 2021 |
In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering Q Wu, QRV Ferry, TA Baeumler, YS Michaels, DM Vitsios, O Habib, ... Nature Communications 8 (1), 2109, 2017 | 12 | 2017 |
Developmental dynamics of the neural crest–mesenchymal axis in creating the thymic microenvironment AE Handel, S Cheuk, F Dhalla, S Maio, T Hübscher, I Rota, ME Deadman, ... Science Advances 8 (19), eabm9844, 2022 | 11 | 2022 |
Combined immunodeficiency with autoimmunity caused by a homozygous missense mutation in inhibitor of nuclear factor 𝛋B kinase alpha (IKKα) W Bainter, V Lougaris, JG Wallace, Y Badran, R Hoyos-Bachiloglu, ... Science immunology 6 (63), eabf6723, 2021 | 11 | 2021 |
The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function BE Oftedal, S Maio, AE Handel, MPJ White, D Howie, S Davis, N Prevot, ... Communications biology 4 (1), 681, 2021 | 8 | 2021 |
Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells F Klein, C Veiga-Villauriz, A Börsch, S Maio, S Palmer, F Dhalla, ... Nature Communications 14 (1), 4071, 2023 | 7 | 2023 |
Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development HE Stefanski, Y Xing, PA Taylor, S Maio, J Henao-Meija, A Williams, ... Plos one 13 (6), e0198871, 2018 | 4 | 2018 |
Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT AR Smith, IA Rota, S Maio, MJ Massaad, TC Lund, LD Notarangelo, ... Blood Advances 1 (23), 2083-2087, 2017 | 4 | 2017 |
RBFOX splicing factors contribute to a broad but selective recapitulation of peripheral tissue splicing patterns in the thymus K Jansen, N Shikama-Dorn, M Attar, S Maio, M Lopopolo, D Buck, ... Genome Research 31 (11), 2022-2034, 2021 | 3 | 2021 |
Diversity in Cortical Thymic Epithelial Cells Occurs through Loss of a Foxn1-Dependent Gene Signature Driven by Stage-Specific Thymocyte Cross-Talk AJ White, SM Parnell, A Handel, S Maio, A Bacon, EJ Cosway, B Lucas, ... The Journal of Immunology 210 (1), 40-49, 2023 | 2 | 2023 |
Rbfox contributes to a conservative program of self-antigen splicing in thymic epithelial cells K Jansen, N Shikama-Dorn, M Attar, S Maio, M Lopopolo, D Buck, ... bioRxiv, 2020 | 1 | 2020 |
A FOXN1 mutation competitively displaces wild-type FOXN1 from higher-order nuclear condensates to cause immunodeficiency IA Rota, AE Handel, F Klein, S Maio, F Dhalla, ME Deadman, S Cheuk, ... bioRxiv, 2021.03. 28.437237, 2021 | | 2021 |
A transcriptomic census reveals that Rbfox contributes to a broad but selective recapitulation of peripheral tissue splicing patterns in the thymus K Jansen, N Shikama-Dorn, M Attar, S Maio, M Lopopolo, D Buck, ... bioRxiv, 2020.03. 06.980870, 2020 | | 2020 |