| Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease J Joubert, GB Foka, BP Repsold, DW Oliver, E Kapp, SF Malan European journal of medicinal chemistry 125, 853-864, 2017 | 122 | 2017 |
| Indazole derivatives and their therapeutic applications: a patent review (2013-2017) I Denya, SF Malan, J Joubert Expert opinion on therapeutic patents 28 (6), 441-453, 2018 | 112 | 2018 |
| Polycyclic cage structures as lipophilic scaffolds for neuroactive drugs J Joubert, WJ Geldenhuys, CJ Van der Schyf, DW Oliver, HG Kruger, ... ChemMedChem 7 (3), 375-384, 2012 | 106 | 2012 |
| Propargylamine as functional moiety in the design of multifunctional drugs for neurodegenerative disorders: MAO inhibition and beyond FT Zindo, J Joubert, SF Malan Future medicinal chemistry 7 (5), 609-629, 2015 | 104 | 2015 |
| Antioxidant properties of 4-quinolones and structurally related flavones J Greeff, J Joubert, SF Malan, S van Dyk Bioorganic & medicinal chemistry 20 (2), 809-818, 2012 | 69 | 2012 |
| Crystal structure, Hirshfeld surface analysis and DFT studies of 5-(adamantan-1-yl)-3-[(4-chlorobenzyl)sulfanyl]-4-methyl-4H-1,2,4-triazole, a potential 11β-HSD1 … LH Al-Wahaibi, J Joubert, O Blacque, NH Al-Shaalan, AA El-Emam Scientific reports 9 (1), 19745, 2019 | 60 | 2019 |
| Novel nitric oxide synthase inhibitors: a patent review J Joubert, SF Malan Expert opinion on therapeutic patents 21 (4), 537-560, 2011 | 53 | 2011 |
| Polycyclic propargylamine and acetylene derivatives as multifunctional neuroprotective agents FT Zindo, QR Barber, J Joubert, JJ Bergh, JP Petzer, SF Malan European journal of medicinal chemistry 80, 122-134, 2014 | 45 | 2014 |
| Synthesis and evaluation of fluorescent heterocyclic aminoadamantanes as multifunctional neuroprotective agents J Joubert, S Van Dyk, IR Green, SF Malan Bioorganic & medicinal chemistry 19 (13), 3935-3944, 2011 | 43 | 2011 |
| Design, synthesis and evaluation of indole derivatives as multifunctional agents against Alzheimer's disease I Denya, SF Malan, AB Enogieru, SI Omoruyi, OE Ekpo, E Kapp, FT Zindo, ... Medchemcomm 9 (2), 357-370, 2018 | 37 | 2018 |
| Synthesis, evaluation and application of polycyclic fluorescent analogues as N-methyl-D-aspartate receptor and voltage gated calcium channel ligands J Joubert, S Van Dyk, IR Green, SF Malan European journal of medicinal chemistry 46 (10), 5010-5020, 2011 | 36 | 2011 |
| Small molecule efflux pump inhibitors in Mycobacterium tuberculosis: a rational drug design perspective E Kapp, SF Malan, J Joubert, SL Sampson Mini reviews in medicinal chemistry 18 (1), 72-86, 2018 | 35 | 2018 |
| Multi-targeted directed ligands for Alzheimer’s disease: Design of novel lead coumarin conjugates BP Repsold, SF Malan, J Joubert, DW Oliver SAR and QSAR in Environmental Research 29 (3), 231-255, 2018 | 32 | 2018 |
| Tacrine, trolox and tryptoline as lead compounds for the design and synthesis of multi-target agents for Alzheimer’s disease therapy GAK Teponnou, J Joubert, SF Malan The Open Medicinal Chemistry Journal 11, 24, 2017 | 31 | 2017 |
| Design, synthesis, biological evaluation and docking studies of sulfonyl isatin derivatives as monoamine oxidase and caspase-3 inhibitors M Tavari, SF Malan, J Joubert MedChemComm 7 (8), 1628-1639, 2016 | 31 | 2016 |
| Versatility of 7-substituted coumarin molecules as antimycobacterial agents, neuronal enzyme inhibitors and neuroprotective agents E Kapp, H Visser, SL Sampson, SF Malan, EM Streicher, GB Foka, ... Molecules 22 (10), 1644, 2017 | 30 | 2017 |
| Molecular modelling and simulation studies of the Mycobacterium tuberculosis multidrug efflux pump protein Rv1258c R Cloete, E Kapp, J Joubert, A Christoffels, SF Malan PLoS One 13 (11), e0207605, 2018 | 28 | 2018 |
| Recent developments in drug design of NO-donor hybrid compounds R Sharma, J Joubert, SF Malan Mini Reviews in Medicinal Chemistry 18 (14), 1175-1198, 2018 | 27 | 2018 |
| Fluorescent polycyclic ligands for nitric oxide synthase (NOS) inhibition J Joubert, S Van Dyk, SF Malan Bioorganic & medicinal chemistry 16 (19), 8952-8958, 2008 | 26 | 2008 |
| Synthesis and biological evaluation of thiazole-based derivatives as potential acetylcholinesterase inhibitors AY Hemaida, GS Hassan, AR Maarouf, J Joubert, AA El-Emam ACS omega 6 (29), 19202-19211, 2021 | 21 | 2021 |
