Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis M Pàez-Ribes, E Allen, J Hudock, T Takeda, H Okuyama, F Viñals, ... Cancer cell 15 (3), 220-231, 2009 | 2817 | 2009 |
Recent advances in cancer therapy: an overview A Urruticoechea, R Alemany, J Balart, A Villanueva, F Vinals, G Capella Current pharmaceutical design 16 (1), 3-10, 2010 | 637 | 2010 |
p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts J Milanini, F Vinals, J Pouysségur, G Pages Journal of Biological Chemistry 273 (29), 18165-18172, 1998 | 402 | 1998 |
Signaling angiogenesis via p42/p44 MAP kinase and hypoxia E Berra, J Milanini, DE Richard, M Le Gall, F Viñals, E Gothié, D Roux, ... Biochemical pharmacology 60 (8), 1171-1178, 2000 | 282 | 2000 |
Transforming growth factor β1 (TGF-β1) promotes endothelial cell survival during in vitro angiogenesis via an autocrine mechanism implicating TGF-α signaling F Viñals, J Pouysségur Molecular and cellular biology 21 (21), 7218-7230, 2001 | 273 | 2001 |
Phosphorylated map kinase (ERK1, ERK2) expression is associated with early tau deposition in neurones and glial cells, but not with increased nuclear DNA vulnerability and cell … I Ferrer, R Blanco, M Carmona, R Ribera, E Goutan, B Puig, MJ Rey, ... Brain Pathology 11 (2), 144-158, 2001 | 264 | 2001 |
Phosphatidylinositol 3-kinase inhibitors block differentiation of skeletal muscle cells P Kaliman, F Viñals, X Testar, M Palacín, A Zorzano Journal of Biological Chemistry 271 (32), 19146-19151, 1996 | 260 | 1996 |
RANK induces epithelial–mesenchymal transition and stemness in human mammary epithelial cells and promotes tumorigenesis and metastasis M Palafox, I Ferrer, P Pellegrini, S Vila, S Hernandez-Ortega, ... Cancer research 72 (11), 2879-2888, 2012 | 224 | 2012 |
A1 Adenosine Receptors Accumulate in Neurodegenerative Structures in Alzheimer's Disease and Mediate Both Amyloid Precursor Protein Processing and Tau … E Angulo, V Casadó, J Mallol, EI Canela, F Viñals, I Ferrer, C Lluis, ... Brain pathology 13 (4), 440-451, 2003 | 223 | 2003 |
Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient … A Méndez-Lucas, P Hyroššová, L Novellasdemunt, F Viñals, JC Perales Journal of Biological Chemistry 289 (32), 22090-22102, 2014 | 211 | 2014 |
p70 S6 kinase-mediated protein synthesis is a critical step for vascular endothelial cell proliferation F Viñals, JC Chambard, J Pouysségur Journal of Biological Chemistry 274 (38), 26776-26782, 1999 | 198 | 1999 |
MPP+ increases α-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells C Gómez-Santos, I Ferrer, J Reiriz, F Viñals, M Barrachina, S Ambrosio Brain research 935 (1-2), 32-39, 2002 | 176 | 2002 |
Signaling angiogenesis via p42/p44 MAP kinase cascade G Pages, J Milanini, DE Richard, E Berra, E Gothie, F Vinals, ... Annals of the New York Academy of Sciences 902 (1), 187-200, 2000 | 166 | 2000 |
Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2 F Viñals, T López-Rovira, JL Rosa, F Ventura FEBS letters 510 (1-2), 99-104, 2002 | 162 | 2002 |
Confluence of vascular endothelial cells induces cell cycle exit by inhibiting p42/p44 mitogen-activated protein kinase activity F Viñals, J Pouysségur Molecular and cellular biology 19 (4), 2763-2772, 1999 | 145 | 1999 |
BMP‐2 decreases Mash1 stability by increasing Id1 expression F Viñals, J Reiriz, S Ambrosio, R Bartrons, JL Rosa, F Ventura The EMBO journal 23 (17), 3527-3537, 2004 | 130 | 2004 |
Resistance to antiangiogenic therapies by metabolic symbiosis in renal cell carcinoma PDX models and patients G Jiménez-Valerio, M Martínez-Lozano, N Bassani, A Vidal, ... Cell reports 15 (6), 1134-1143, 2016 | 119 | 2016 |
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis H Serra, I Chivite, A Angulo-Urarte, A Soler, JD Sutherland, ... Nature communications 6 (1), 7935, 2015 | 114 | 2015 |
A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect P Lopez-Serra, M Marcilla, A Villanueva, A Ramos-Fernandez, A Palau, ... Nature communications 5 (1), 3608, 2014 | 112 | 2014 |
Lurbinectedin (PM01183), a new DNA minor groove binder, inhibits growth of orthotopic primary graft of cisplatin-resistant epithelial ovarian cancer A Vidal, C Muñoz, MJ Guillén, J Moretó, S Puertas, M Martínez-Iniesta, ... Clinical Cancer Research 18 (19), 5399-5411, 2012 | 105 | 2012 |