The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel G Stephan, L Huang, Y Tang, S Vilotti, E Fabbretti, Y Yu, W Nörenberg, ... Nature communications 9 (1), 1354, 2018 | 60 | 2018 |
Functional impact of intramolecular cleavage and dissociation of adhesion G protein–coupled receptor GPR133 (ADGRD1) on canonical signaling JD Frenster, G Stephan, N Ravn-Boess, D Bready, J Wilcox, B Kieslich, ... Journal of Biological Chemistry 296, 2021 | 33 | 2021 |
Flexible subunit stoichiometry of functional human P2X2/3 heteromeric receptors M Kowalski, R Hausmann, J Schmid, A Dopychai, G Stephan, Y Tang, ... Neuropharmacology 99, 115-130, 2015 | 26 | 2015 |
Expression profiling of the adhesion G protein-coupled receptor GPR133 (ADGRD1) in glioma subtypes JD Frenster, M Kader, S Kamen, J Sun, L Chiriboga, J Serrano, D Bready, ... Neuro-oncology advances 2 (1), vdaa053, 2020 | 22 | 2020 |
The n terminus of adhesion g protein–coupled receptor gpr126/adgrg6 as allosteric force integrator J Mitgau, J Franke, C Schinner, G Stephan, S Berndt, DG Placantonakis, ... Frontiers in Cell and Developmental Biology 10, 873278, 2022 | 20 | 2022 |
Activation of the adhesion g protein–coupled receptor gpr133 by antibodies targeting its n-terminus G Stephan, JD Frenster, I Liebscher, DG Placantonakis Journal of Biological Chemistry 298 (6), 2022 | 17 | 2022 |
Adhesion G protein-coupled receptors in glioblastoma G Stephan, N Ravn-Boess, DG Placantonakis Neuro-oncology advances 3 (1), vdab046, 2021 | 15 | 2021 |
The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability N Ravn-Boess, N Roy, T Hattori, D Bready, H Donaldson, C Lawson, ... Cell reports 42 (11), 2023 | 10 | 2023 |
PTK7 is a positive allosteric modulator of GPR133 signaling in glioblastoma JD Frenster, H Erdjument-Bromage, G Stephan, N Ravn-Boess, S Wang, ... Cell reports 42 (7), 2023 | 10 | 2023 |
Inter-subunit disulfide locking of the human P2X3 receptor elucidates ectodomain movements associated with channel gating G Stephan, M Kowalski-Jahn, C Zens, G Schmalzing, P Illes, ... Purinergic signalling 12, 221-233, 2016 | 6 | 2016 |
Modulation of GPR133 (ADGRD1) signaling by its intracellular interaction partner extended synaptotagmin 1 (ESYT1) G Stephan, H Erdjument-Bromage, W Liu, JD Frenster, N Ravn-Boess, ... bioRxiv, 2023 | 1 | 2023 |
PTK7 is a positive allosteric modulator of GPR133 (ADGRD1) signaling in GBM JD Frenster, H Erdjument-Bromage, W Liu, G Stephan, N Ravn-Boess, ... bioRxiv, 2022.06. 15.496232, 2022 | 1 | 2022 |
CSIG-07. ACTIVATION OF THE ADHESION G PROTEIN-COUPLED RECEPTOR GPR133 BY ANTIBODIES AGAINST THE N-TERMINUS Gabriele Stephan, Joshua Frenster, Niklas Ravn-Boess, Devin Bready, Jordan ... Neuro-Oncology 23 (Supplement_6), vi34-vi34, 2021 | 1 | 2021 |
Activation of the adhesion GPCR GPR133 (ADGRD1) by antibodies targeting the N-terminus G Stephan, JD Frenster, I Liebscher, DG Placantonakis bioRxiv, 2021.09. 13.460139, 2021 | 1 | 2021 |
CSIG-22. PHARMACOLOGIC INHIBITION AND KNOCKDOWN OF CAMK2 IMPAIR GROWTH OF PATIENT-DERIVED GLIOBLASTOMA CULTURES R Ronnen, S Wang, S Haddock, N Ravn-Boess, D Golub, G Stephan, ... Neuro-Oncology 26 (Supplement_8), viii68-viii68, 2024 | | 2024 |
Modulation of GPR133 (ADGRD1) signaling by its intracellular interaction partner extended synaptotagmin 1 G Stephan, S Haddock, S Wang, H Erdjument-Bromage, W Liu, ... Cell Reports 43 (5), 2024 | | 2024 |
PTK7 is a positive allosteric modulator of GPR133 signaling in glioblastoma. JD Frenster, H Erdjument-Bromage, G Stephan, N Ravn-Boess, S Wang, ... Cell Reports 42 (7), 112679-112679, 2023 | | 2023 |
CSIG-27. MODULATION OF GPR133 (ADGRD1) SIGNALING BY ITS INTRACELLULAR INTERACTION PARTNER EXTENDED SYNAPTOTAGMIN 1 (ESYT1) G Stephan, H Erdjument-Bromage, W Liu, J Frenster, T Neubert, D Fenyo, ... Neuro-Oncology 24 (Suppl 7), vii44, 2022 | | 2022 |
TMET-19. DEFINING A NOVEL ROLE FOR CD97 IN REGULATING GBM GLYCOLYTIC METABOLISM N Ravn-Boess, N Bhowmick, T Hattori, V Prakash, G Stephan, J Frenster, ... Neuro-Oncology 24 (Suppl 7), vii265, 2022 | | 2022 |
CSIG-05. DISSOCIATION OF THE INTRAMOLECULARLY CLEAVED N-AND C-TERMINAL FRAGMENTS OF ADHESION G PROTEIN-COUPLED RECEPTOR GPR133 (ADGRD1) INCREASES ITS CANONICAL SIGNALING IN … J Frenster, G Stephan, N Ravn-Boess, D Bready, J Wilcox, I Liebscher, ... Neuro-Oncology 23 (Supplement_6), vi34-vi34, 2021 | | 2021 |