An enhanced CRISPR repressor for targeted mammalian gene regulation NC Yeo, A Chavez, A Lance-Byrne, Y Chan, D Menn, D Milanova, ... Nature methods 15 (8), 611-616, 2018 | 444 | 2018 |
Cas9 gRNA engineering for genome editing, activation and repression S Kiani, A Chavez, M Tuttle, RN Hall, R Chari, D Ter-Ovanesyan, J Qian, ... Nature methods 12 (11), 1051-1054, 2015 | 354 | 2015 |
CRISPR transcriptional repression devices and layered circuits in mammalian cells S Kiani, J Beal, MR Ebrahimkhani, J Huh, RN Hall, Z Xie, Y Li, R Weiss Nature methods 11 (7), 723-726, 2014 | 237 | 2014 |
Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease MR Ebrahimkhani, F Oakley, LB Murphy, J Mann, A Moles, MJ Perugorria, ... Nature medicine 17 (12), 1668-1673, 2011 | 230 | 2011 |
Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes SR Ferdosi, R Ewaisha, F Moghadam, S Krishna, JG Park, ... Nature communications 10 (1), 1842, 2019 | 175 | 2019 |
Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6 P Guye, MR Ebrahimkhani, N Kipniss, JJ Velazquez, E Schoenfeld, ... Nature communications 7 (1), 10243, 2016 | 167 | 2016 |
Bioreactor technologies to support liver function in vitro MR Ebrahimkhani, JAS Neiman, MSB Raredon, DJ Hughes, LG Griffith Advanced drug delivery reviews 69, 132-157, 2014 | 154 | 2014 |
Cross‐presentation of antigen by diverse subsets of murine liver cells MR Ebrahimkhani, I Mohar, IN Crispe Hepatology 54 (4), 1379-1387, 2011 | 118 | 2011 |
Naltrexone, an opioid receptor antagonist, attenuates liver fibrosis in bile duct ligated rats MR Ebrahimkhani, S Kiani, F Oakley, T Kendall, A Shariftabrizi, ... Gut 55 (11), 1606-1616, 2006 | 100 | 2006 |
Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor U Sarkar, D Rivera-Burgos, EM Large, DJ Hughes, KC Ravindra, RL Dyer, ... Drug metabolism and disposition 43 (7), 1091-1099, 2015 | 88 | 2015 |
Effect of morphine on ischemia-reperfusion injury: experimental study in testicular torsion rat model AH Salmasi, A Beheshtian, S Payabvash, S Demehri, MR Ebrahimkhani, ... Urology 66 (6), 1338-1342, 2005 | 78 | 2005 |
Human biomimetic liver microphysiology systems in drug development and precision medicine A Gough, A Soto-Gutierrez, L Vernetti, MR Ebrahimkhani, AM Stern, ... Nature reviews Gastroenterology & hepatology 18 (4), 252-268, 2021 | 76 | 2021 |
Gene regulatory network analysis and engineering directs development and vascularization of multilineage human liver organoids JJ Velazquez, R LeGraw, F Moghadam, Y Tan, J Kilbourne, JC Maggiore, ... Cell systems 12 (1), 41-55. e11, 2021 | 74 | 2021 |
The c‐Rel subunit of nuclear factor‐κB regulates murine liver inflammation, wound‐healing, and hepatocyte proliferation RG Gieling, AM Elsharkawy, JH Caamaño, DE Cowie, MC Wright, ... Hepatology 51 (3), 922-931, 2010 | 70 | 2010 |
Isolation of non-parenchymal cells from the mouse liver I Mohar, KJ Brempelis, SA Murray, MR Ebrahimkhani, IN Crispe Malaria Vaccines: Methods and Protocols, 3-17, 2015 | 65 | 2015 |
Nitric oxide: a new concept in chronic sinusitis pathogenesis M Naraghi, AF Deroee, MR Ebrahimkhani, S Kiani, AR Dehpour American journal of otolaryngology 28 (5), 334-337, 2007 | 64 | 2007 |
Galactosylated LDL nanoparticles: a novel targeting delivery system to deliver antigen to macrophages and enhance antigen specific T cell responses F Wu, SA Wuensch, M Azadniv, MR Ebrahimkhani, IN Crispe Molecular pharmaceutics 6 (5), 1506-1517, 2009 | 54 | 2009 |
Hydrogen sulphide and the hyperdynamic circulation in cirrhosis: a hypothesis MR Ebrahimkhani, AR Mani, K Moore Gut 54 (12), 1668-1671, 2005 | 54 | 2005 |
CRISPR-based synthetic transcription factors in vivo: the future of therapeutic cellular programming M Pandelakis, E Delgado, MR Ebrahimkhani Cell systems 10 (1), 1-14, 2020 | 53 | 2020 |
Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney MR Ebrahimkhani, A Daneshmand, A Mazumder, M Allocca, JA Calvo, ... Proceedings of the National Academy of Sciences 111 (45), E4878-E4886, 2014 | 53 | 2014 |