| The bone marrow microenvironment at single-cell resolution AN Tikhonova, I Dolgalev, H Hu, KK Sivaraj, E Hoxha, ... Nature 569 (7755), 222-228, 2019 | 757 | 2019 |
| CXCL12-producing vascular endothelial niches control acute T cell leukemia maintenance LA Pitt, AN Tikhonova, H Hu, T Trimarchi, B King, Y Gong, ... Cancer cell 27 (6), 755-768, 2015 | 265 | 2015 |
| Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis MG Poulos, P Guo, NM Kofler, S Pinho, MC Gutkin, A Tikhonova, I Aifantis, ... Cell reports 4 (5), 1022-1034, 2013 | 263 | 2013 |
| Extensive remodeling of the immune microenvironment in B cell acute lymphoblastic leukemia MT Witkowski, I Dolgalev, NA Evensen, C Ma, T Chambers, KG Roberts, ... Cancer cell 37 (6), 867-882. e12, 2020 | 132 | 2020 |
| Lck availability during thymic selection determines the recognition specificity of the T cell repertoire F Van Laethem, AN Tikhonova, LA Pobezinsky, X Tai, MY Kimura, ... Cell 154 (6), 1326-1341, 2013 | 115 | 2013 |
| αβ T cell receptors that do not undergo major histocompatibility complex-specific thymic selection possess antibody-like recognition specificities AN Tikhonova, F Van Laethem, K Hanada, J Lu, LA Pobezinsky, C Hong, ... Immunity 36 (1), 79-91, 2012 | 111 | 2012 |
| MHC restriction is imposed on a diverse T cell receptor repertoire by CD4 and CD8 co-receptors during thymic selection F Van Laethem, AN Tikhonova, A Singer Trends in immunology 33 (9), 437-441, 2012 | 98 | 2012 |
| In vivo mapping of notch pathway activity in normal and stress hematopoiesis P Oh, C Lobry, J Gao, A Tikhonova, E Loizou, J Manent, B Van Handel, ... Cell stem cell 13 (2), 190-204, 2013 | 94 | 2013 |
| Interleukin-17 governs hypoxic adaptation of injured epithelium P Konieczny, Y Xing, I Sidhu, I Subudhi, KP Mansfield, B Hsieh, ... Science 377 (6602), eabg9302, 2022 | 89 | 2022 |
| Molecular constraints on CDR3 for thymic selection of MHC-restricted TCRs from a random pre-selection repertoire J Lu, F Van Laethem, A Bhattacharya, M Craveiro, I Saba, J Chu, NC Love, ... Nature communications 10 (1), 1019, 2019 | 69 | 2019 |
| An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia A Lasry, B Nadorp, M Fornerod, D Nicolet, H Wu, CJ Walker, Z Sun, ... Nature cancer 4 (1), 27-42, 2023 | 66 | 2023 |
| Connecting the dots: resolving the bone marrow niche heterogeneity I Dolgalev, AN Tikhonova Frontiers in cell and developmental biology 9, 622519, 2021 | 64 | 2021 |
| The E3 ubiquitin ligase SPOP controls resolution of systemic inflammation by triggering MYD88 degradation M Guillamot, D Ouazia, I Dolgalev, ST Yeung, N Kourtis, Y Dai, K Corrigan, ... Nature immunology 20 (9), 1196-1207, 2019 | 51 | 2019 |
| STIM1 and STIM2 mediate cancer-induced inflammation in T cell acute lymphoblastic leukemia S Saint Fleur-Lominy, M Maus, M Vaeth, I Lange, I Zee, D Suh, C Liu, ... Cell reports 24 (11), 3045-3060. e5, 2018 | 28 | 2018 |
| Tissue-resident macrophages promote early dissemination of multiple myeloma via IL-6 and TNFα I Akhmetzyanova, T Aaron, P Galbo, A Tikhonova, I Dolgalev, M Tanaka, ... Blood Advances 5 (18), 3592-3608, 2021 | 22 | 2021 |
| The activation threshold of CD4+ T cells is defined by TCR/peptide-MHC class II interactions in the thymic medulla TL Stephen, A Tikhonova, JM Riberdy, TM Laufer The Journal of Immunology 183 (9), 5554-5562, 2009 | 22 | 2009 |
| Cell-by-cell deconstruction of stem cell niches AN Tikhonova, A Lasry, R Austin, I Aifantis Cell stem cell 27 (1), 19-34, 2020 | 21 | 2020 |
| Rational drug combinations with CDK4/6 inhibitors in acute lymphoblastic leukemia KL Bride, H Hu, A Tikhonova, TJ Fuller, TL Vincent, R Shraim, MM Li, ... Haematologica 107 (8), 1746, 2022 | 18 | 2022 |
| Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity C O’Brien, T Ling, JM Berman, R Culp-Hill, JA Reisz, V Rondeau, ... Haematologica 108 (9), 2343, 2023 | 10 | 2023 |
| Structure of MHC-Independent TCRs and their recognition of native antigen CD155 J Lu, F Van Laethem, I Saba, J Chu, AN Tikhonova, A Bhattacharya, ... The Journal of Immunology 204 (12), 3351-3359, 2020 | 5 | 2020 |
