Developments in intervertebral disc disease research: pathophysiology, mechanobiology, and therapeutics KT Weber, TD Jacobsen, R Maidhof, J Virojanapa, C Overby, O Bloom, ... Current reviews in musculoskeletal medicine 8, 18-31, 2015 | 103 | 2015 |
Inflammation induces irreversible biophysical changes in isolated nucleus pulposus cells R Maidhof, T Jacobsen, A Papatheodorou, NO Chahine PloS one 9 (6), e99621, 2014 | 63 | 2014 |
High mobility group box‐1 induces pro‐inflammatory signaling in human nucleus pulposus cells via toll‐like receptor 4‐dependent pathway BS Shah, KG Burt, T Jacobsen, TD Fernandes, DO Alipui, KT Weber, ... Journal of Orthopaedic Research® 37 (1), 220-231, 2019 | 49 | 2019 |
Effects of inflammation on multiscale biomechanical properties of cartilaginous cells and tissues QT Nguyen, TD Jacobsen, NO Chahine ACS Biomaterials Science & Engineering 3 (11), 2644-2656, 2017 | 40 | 2017 |
Timing of mesenchymal stem cell delivery impacts the fate and therapeutic potential in intervertebral disc repair R Maidhof, A Rafiuddin, F Chowdhury, T Jacobsen, NO Chahine Journal of Orthopaedic Research 35 (1), 32-40, 2017 | 35 | 2017 |
Actomyosin contractility confers mechanoprotection against TNFα-induced disruption of the intervertebral disc PA Hernandez, TD Jacobsen, NO Chahine Science advances 6 (34), eaba2368, 2020 | 23 | 2020 |
Three-dimensional-printed flexible scaffolds have tunable biomimetic mechanical properties for intervertebral disc tissue engineering SL Marshall, TD Jacobsen, E Emsbo, A Murali, K Anton, JZ Liu, HH Lu, ... ACS biomaterials science & engineering 7 (12), 5836-5849, 2021 | 22 | 2021 |
Avidin grafted dextran nanostructure enables a month-long intra-discal retention EK Wagner, A Vedadghavami, TD Jacobsen, SA Goel, NO Chahine, ... Scientific reports 10 (1), 12017, 2020 | 20 | 2020 |
Inhibition of toll-like receptor 4 protects against inflammation-induced mechanobiological alterations to intervertebral disc cells TD Jacobsen, PA Hernandez, NO Chahine European cells & materials 41, 576, 2021 | 9 | 2021 |
Confocal scanning of intervertebral disc cells in 3D: Inside alginate beads and in native microenvironment PA Hernandez, TD Jacobsen, Z Barati, NO Chahine Jor Spine 3 (4), e1106, 2020 | 7 | 2020 |
Toward defining the role of the synovium in mitigating normal articular cartilage wear and tear MJ Pellicore, LR Gangi, LA Murphy, AJ Lee, T Jacobsen, HM Kenawy, ... Journal of biomechanics 148, 111472, 2023 | 5 | 2023 |
Transient neonatal shoulder paralysis causes early osteoarthritis in a mouse model LA Forrester, F Fang, T Jacobsen, Y Hu, I Kurtaliaj, BD Roye, ... Journal of Orthopaedic Research® 40 (9), 1981-1992, 2022 | 2 | 2022 |
Anti-inflammatory agents prevent intervertebral disc cell mechanobiological alterations T Jacobsen, N Chahine Global Spine Journal 6 (1_suppl), s-0036-1582599-s-0036-1582599, 2016 | 2 | 2016 |
Relationship Between Inflammatory Stimulation and Cell Biomechanics in Intervertebral Disc Degeneration TD Jacobsen Columbia University, 2022 | 1 | 2022 |
P8. Responsiveness of patient derived intervertebral disc cells to mechanobiological treatment N Chahine, T Jacobsen, E Leung, RA Lehman The Spine Journal 22 (9), S129, 2022 | | 2022 |
88. Cell stiffness decreases with severity of disc degeneration and inflammatory stimulation N Chahine, E Leung, M Cerpa, M Vulapalli, V Boddapati, T Jacobsen, ... The Spine Journal 20 (9), S43, 2020 | | 2020 |