| New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure YH Tseng, E Kokkotou, TJ Schulz, TL Huang, JN Winnay, CM Taniguchi, ... Nature 454 (7207), 1000-1004, 2008 | 1293 | 2008 |
| Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene WS Chen, PZ Xu, K Gottlob, ML Chen, K Sokol, T Shiyanova, I Roninson, ... Genes & development 15 (17), 2203-2208, 2001 | 1224 | 2001 |
| Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance N Kamei, K Tobe, R Suzuki, M Ohsugi, T Watanabe, N Kubota, ... Journal of biological chemistry 281 (36), 26602-26614, 2006 | 1105 | 2006 |
| Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake N Kubota, W Yano, T Kubota, T Yamauchi, S Itoh, H Kumagai, H Kozono, ... Cell metabolism 6 (1), 55-68, 2007 | 1046 | 2007 |
| Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity A Tsuchida, T Yamauchi, Y Ito, Y Hada, T Maki, S Takekawa, J Kamon, ... Journal of Biological Chemistry 279 (29), 30817-30822, 2004 | 751 | 2004 |
| Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. N Kubota, K Tobe, Y Terauchi, K Eto, T Yamauchi, R Suzuki, Y Tsubamoto, ... Diabetes 49 (11), 1880-1889, 2000 | 661 | 2000 |
| Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis SB Biddinger, A Hernandez-Ono, C Rask-Madsen, JT Haas, JO Alemán, ... Cell metabolism 7 (2), 125-134, 2008 | 567 | 2008 |
| Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation Y Oishi, I Manabe, K Tobe, K Tsushima, T Shindo, K Fujiu, G Nishimura, ... Cell metabolism 1 (1), 27-39, 2005 | 538 | 2005 |
| Glucokinase and IRS-2 are required for compensatory β cell hyperplasia in response to high-fat diet–induced insulin resistance Y Terauchi, I Takamoto, N Kubota, J Matsui, R Suzuki, K Komeda, A Hara, ... The Journal of clinical investigation 117 (1), 246-257, 2007 | 398 | 2007 |
| Insulin receptor substrate 2 plays a crucial role in β cells and the hypothalamus N Kubota, Y Terauchi, K Tobe, W Yano, R Suzuki, K Ueki, I Takamoto, ... The Journal of clinical investigation 114 (7), 917-927, 2004 | 289 | 2004 |
| Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation H Miki, T Yamauchi, RYO Suzuki, K Komeda, A Tsuchida, N Kubota, ... Molecular and cellular biology 21 (7), 2521-2532, 2001 | 261 | 2001 |
| Diabetes and insulin in regulation of brain cholesterol metabolism R Suzuki, K Lee, E Jing, SB Biddinger, JG McDonald, TJ Montine, S Craft, ... Cell metabolism 12 (6), 567-579, 2010 | 195 | 2010 |
| Increased expression of the sterol regulatory element-binding protein-1 gene in insulin receptor substrate-2−/− mouse liver K Tobe, R Suzuki, M Aoyama, T Yamauchi, J Kamon, N Kubota, ... Journal of Biological Chemistry 276 (42), 38337-38340, 2001 | 186 | 2001 |
| Specific roles of the p110α isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation VR Sopasakis, P Liu, R Suzuki, T Kondo, J Winnay, TT Tran, T Asano, ... Cell Metabolism 11 (3), 220-230, 2010 | 179 | 2010 |
| PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans O Bezy, TT Tran, J Pihlajamäki, R Suzuki, B Emanuelli, J Winnay, MA Mori, ... The Journal of clinical investigation 121 (6), 2504-2517, 2011 | 174 | 2011 |
| Lack of insulin receptor substrate-2 causes progressive neointima formation in response to vessel injury T Kubota, N Kubota, M Moroi, Y Terauchi, T Kobayashi, K Kamata, ... Circulation 107 (24), 3073-3080, 2003 | 146 | 2003 |
| Overexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistance B Emanuelli, D Eberlé, R Suzuki, CR Kahn Proceedings of the National Academy of Sciences 105 (9), 3545-3550, 2008 | 134 | 2008 |
| The RNA methyltransferase complex of WTAP, METTL3, and METTL14 regulates mitotic clonal expansion in adipogenesis M Kobayashi, M Ohsugi, T Sasako, M Awazawa, T Umehara, A Iwane, ... Molecular and cellular biology 38 (16), e00116-18, 2018 | 132 | 2018 |
| Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway KL Townsend, R Suzuki, TL Huang, E Jing, TJ Schulz, K Lee, ... The FASEB Journal 26 (5), 2187, 2012 | 129 | 2012 |
| A qualitative study on the impact of internalized stigma on type 2 diabetes self-management A Kato, Y Fujimaki, S Fujimori, Y Izumida, R Suzuki, K Ueki, T Kadowaki, ... Patient Education and Counseling 99 (7), 1233-1239, 2016 | 111 | 2016 |
