Inflammation and esophageal carcinogenesis MMM Abdel-Latif, S Duggan, JV Reynolds, D Kelleher Current opinion in pharmacology 9 (4), 396-404, 2009 | 133 | 2009 |
Tribbles 3: a novel regulator of TLR2-mediated signaling in response to Helicobacter pylori lipopolysaccharide SM Smith, AP Moran, SP Duggan, SE Ahmed, AS Mohamed, HJ Windle, ... The Journal of Immunology 186 (4), 2462-2471, 2011 | 101 | 2011 |
Gene expression analysis of diagnostic biopsies predicts pathological response to neoadjuvant chemoradiotherapy of esophageal cancer SG Maher, CM Gillham, SP Duggan, PC Smyth, N Miller, C Muldoon, ... Annals of surgery 250 (5), 729-737, 2009 | 92 | 2009 |
Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells E Looby, MMM Abdel-Latif, V Athié-Morales, S Duggan, A Long, ... BMC cancer 9, 1-15, 2009 | 80 | 2009 |
Low pH induces co-ordinate regulation of gene expression in oesophageal cells SP Duggan, WM Gallagher, EJP Fox, MM Abdel-Latif, JV Reynolds, ... Carcinogenesis 27 (2), 319-327, 2006 | 70 | 2006 |
Obstacles for T-lymphocytes in the tumour microenvironment: Therapeutic challenges, advances and opportunities beyond immune checkpoint NK Verma, BHS Wong, ZS Poh, A Udayakumar, R Verma, RKJ Goh, ... EBioMedicine 83, 2022 | 52 | 2022 |
New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid F Májer, R Sharma, C Mullins, L Keogh, S Phipps, S Duggan, D Kelleher, ... Bioorganic & medicinal chemistry 22 (1), 256-268, 2014 | 38 | 2014 |
An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, downregulated in Barrett's oesophagus, which regulates NF-κB activation and … SP Duggan, FM Behan, M Kirca, S Smith, JV Reynolds, A Long, ... Carcinogenesis 31 (5), 936-945, 2010 | 38 | 2010 |
High sensitivity cytokine detection in acute coronary syndrome reveals up-regulation of interferon gamma and interleukin-10 post myocardial infarction KD Patel, SP Duggan, CA Currid, WM Gallagher, R McManus, D Kelleher, ... Clinical Immunology 133 (2), 251-256, 2009 | 22 | 2009 |
siRNA library screening identifies a druggable immune-signature driving esophageal adenocarcinoma cell growth SP Duggan, C Garry, FM Behan, S Phipps, H Kudo, M Kirca, A Zaheer, ... Cellular and Molecular Gastroenterology and Hepatology 5 (4), 569-590, 2018 | 21 | 2018 |
Tribbles 3: a novel regulator of TLR2-mediated signaling in response to SM Smith, AP Moran, SP Duggan, SE Ahmed, AS Mohamed, HJ Windle, ... Helicobacter pylori, 2462-2471, 0 | 21 | |
The characterization of an intestine-like genomic signature maintained during Barrett’s-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival SP Duggan, FM Behan, M Kirca, A Zaheer, SA McGarrigle, JV Reynolds, ... Scientific Reports 6 (1), 32638, 2016 | 19 | 2016 |
Combination therapy using inhalable GapmeR and recombinant ACE2 for COVID-19 NK Verma, MHUT Fazil, SP Duggan, D Kelleher Frontiers in Molecular Biosciences 7, 197, 2020 | 11 | 2020 |
High Content imaging of Barrett’s-associated high-grade dysplasia cells after siRNA library screening reveals acid-responsive regulators of cellular transitions SM Phipps, CE Garry, S Kamal, JD Johnson, J Gilmer, A Long, D Kelleher, ... Cellular and Molecular Gastroenterology and Hepatology 10 (3), 601-622, 2020 | 5 | 2020 |
The immune underpinnings of Barrett’s-associated adenocarcinogenesis: a retrial of nefarious immunologic co-conspirators L Tambunting, D Kelleher, SP Duggan Cellular and Molecular Gastroenterology and Hepatology 13 (5), 1297-1315, 2022 | 4 | 2022 |
Inherited syndromes predisposing to inflammation and GI Cancer S Duggan, D Prichard, M Kirca, D Kelleher Inflammation and Gastrointestinal Cancers, 35-50, 2011 | 4 | 2011 |
S1635 Loss of Bile Acid Responsive Gene Retinoic Acid Receptor-Related Orphan Receptor A (Rora) in Barrett's Metaplasia, Implications for Refluxed Induced Signaling in … SP Duggan, M Kirca, FM Behan, DP Kelleher Gastroenterology 5 (138), S-243, 2010 | 1 | 2010 |
S1638 A Novel Genomic Intestinal Filter Identifies NR5A2 and TEAD1 as Novel Intestinal Transcription Factors With the Potential to Interact With Gata6 in the Development of … M Kirca, SP Duggan, A Zaheer, DP Kelleher Gastroenterology 5 (138), S-243-S-244, 2010 | 1 | 2010 |
223 Toll-Like Receptor 2-Dependent Chemokine Induction in Epithelial Cells By Lipopolysaccharide Contained in Helicobacter pylori Outer Membrane Vesicles SM Smith, AP Moran, E Mullaney, SP Duggan, HJ Windle, LA O'Neill, ... Gastroenterology 5 (136), A-42, 2009 | 1 | 2009 |
POINT-COUNTERPOINT W Zhou, S Anakk, B Bhushan, U Apte, L Tambunting, D Kelleher, ... | 1 | |