| Metabolic enzymes moonlighting in the nucleus: metabolic regulation of gene transcription AE Boukouris, SD Zervopoulos, ED Michelakis Trends in biochemical sciences 41 (8), 712-730, 2016 | 282 | 2016 |
| Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients ED Michelakis, V Gurtu, L Webster, G Barnes, G Watson, L Howard, ... Science translational medicine 9 (413), eaao4583, 2017 | 272 | 2017 |
| The degree of liver injury determines the role of p21 in liver regeneration and hepatocarcinogenesis in mice LE Buitrago‐Molina, S Marhenke, T Longerich, AD Sharma, AE Boukouris, ... Hepatology 58 (3), 1143-1152, 2013 | 100 | 2013 |
| Tissue-specific regulation of p53 by PKM2 is redox dependent and provides a therapeutic target for anthracycline-induced cardiotoxicity B Saleme, V Gurtu, Y Zhang, A Kinnaird, AE Boukouris, K Gopal, ... Science translational medicine 11 (478), eaau8866, 2019 | 67 | 2019 |
| Activity of the mTOR inhibitor RAD001, the dual mTOR and PI3‐kinase inhibitor BEZ235 and the PI3‐kinase inhibitor BKM120 in hepatocellular carcinoma MM Kirstein, AE Boukouris, D Pothiraju, LE Buitrago‐Molina, S Marhenke, ... Liver International 33 (5), 780-793, 2013 | 49 | 2013 |
| Latest evidence on immune checkpoint inhibitors in metastatic colorectal cancer: A 2022 update AE Boukouris, M Theochari, D Stefanou, A Papalambros, E Felekouras, ... Critical reviews in oncology/hematology 173, 103663, 2022 | 48 | 2022 |
| MFN2-driven mitochondria-to-nucleus tethering allows a non-canonical nuclear entry pathway of the mitochondrial pyruvate dehydrogenase complex SD Zervopoulos, AE Boukouris, B Saleme, A Haromy, S Tejay, ... Molecular Cell 82 (5), 1066-1077. e7, 2022 | 35 | 2022 |
| SNPs for genes encoding the mitochondrial proteins Sirtuin3 and uncoupling protein 2 are associated with disease severity, type 2 diabetes, and outcomes in patients with … Y Zhang, SD Zervopoulos, AE Boukouris, MA Lorenzana‐Carrillo, ... Journal of the American Heart Association 10 (23), e020451, 2021 | 9 | 2021 |
| p53‐Mediated Repression of the PGC1A (PPARG Coactivator 1α) and APLNR (Apelin Receptor) Signaling Pathways Limits Fatty Acid Oxidation Energetics: Implications for Cardio‐oncology B Saleme, SK Das, Y Zhang, AE Boukouris, MA Lorenzana Carrillo, ... Journal of the American Heart Association 9 (15), e017247, 2020 | 9 | 2020 |
| A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer AE Boukouris, Y Zhang, B Saleme, A Kinnaird, YY Zhao, Y Liu, ... Cell Reports 38 (11), 2022 | 7 | 2022 |
| Interaction with p53 explains a pro-proliferative function for VHL in cancer A Kinnaird, AE Boukouris, B Saleme, P Dromparis, SD Zervopoulos, ... Journal of Molecular Medicine 98, 1269-1278, 2020 | 6 | 2020 |
| Endothelin receptor blocker reverses breast cancer–induced cardiac remodeling ZH Maayah, M Ferdaoussi, AE Boukouris, S Takahara, SK Das, M Khairy, ... Cardio Oncology 5 (5), 686-700, 2023 | 5 | 2023 |
| Loss of the fructose transporter SLC2A5 inhibits cancer cell migration J Groenendyk, K Stoletov, T Paskevicius, W Li, N Dai, M Pujol, E Busaan, ... Frontiers in Cell and Developmental Biology 10, 896297, 2022 | 4 | 2022 |
| Prognosis of hospitalized patients during different pandemic waves in Greece: Omicron innocent until proven guilty? IE Michelakis, AE Boukouris, A Komodromou, S Foteinou, M Dafni European Journal of Internal Medicine 121, 139-142, 2024 | | 2024 |
| Case report: The devil was hidden in the mastocytes–an unusually fulminant case of indolent systemic mastocytosis in a 45-year-old patient, missed for almost 20 years AE Boukouris, I Michelakis, D Metaxas, G Karapati, G Kanellis, A Lioni, ... Frontiers in Immunology 14, 1134587, 2023 | | 2023 |
