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Timothy D. Knab
Timothy D. Knab
Metrum Research Group
在 pitt.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Positive charge of “sticky” peptides and proteins impedes release from negatively charged PLGA matrices
SC Balmert, AC Zmolek, AJ Glowacki, TD Knab, SN Rothstein, ...
Journal of Materials Chemistry B 3 (23), 4723-4734, 2015
432015
A quantitative modeling and simulation framework to support candidate and dose selection of anti‐SARS‐CoV‐2 monoclonal antibodies to advance bamlanivimab into a first‐in‐human …
E Chigutsa, E Jordie, M Riggs, A Nirula, A Elmokadem, T Knab, JY Chien
Clinical Pharmacology & Therapeutics 111 (3), 595-604, 2022
242022
A systems approach to modeling drug release from polymer microspheres to accelerate in vitro to in vivo translation
TD Knab, SR Little, RS Parker
Journal of Controlled Release 211, 74-84, 2015
192015
Zone model predictive control and moving horizon estimation for the regulation of blood glucose in critical care patients
TD Knab, G Clermont, RS Parker
IFAC-PapersOnLine 48 (8), 1002-1007, 2015
172015
A “virtual patient” cohort and mathematical model of glucose dynamics in critical care
TD Knab, G Clermont, RS Parker
IFAC-PapersOnLine 49 (26), 1-7, 2016
112016
Modeling glucose and subcutaneous insulin dynamics in critical care
A Pritchard-Bell, G Clermont, TD Knab, J Maalouf, M Vilkhovoy, RS Parker
Control Engineering Practice 58, 268-275, 2017
92017
Bayesian pbpk modeling using r/stan/torsten and julia/sciml/turing. jl
A Elmokadem, Y Zhang, T Knab, E Jordie, WR Gillespie
CPT: Pharmacometrics & Systems Pharmacology 12 (3), 300-310, 2023
72023
CD19 expression by IHC alone is not a predictor of response to loncastuximab tesirine: results from the LOTIS-2 clinical trial and quantitative systems pharmacology modeling
PF Caimi, M Hamadani, C Carlo-Stella, M Nickaeen, E Jordie, K Utsey, ...
Blood 140 (Supplement 1), 9548-9550, 2022
62022
Landscape analysis for a neonatal disease progression model of bronchopulmonary dysplasia: Leveraging clinical trial experience and real-world data
JS Barrett, M Cala Pane, T Knab, W Roddy, J Beusmans, E Jordie, ...
Frontiers in Pharmacology 13, 988974, 2022
32022
Toxicity-centric cancer chemotherapy treatment design
JT Liparulo, TD Knab, RS Parker
IFAC-PapersOnLine 53 (2), 16353-16358, 2020
32020
The impact of a responsive endogenous pancreas in critical care glucose control
RS Parker, TD Knab, G Clermont
2018 Annual American Control Conference (ACC), 3595-3601, 2018
32018
In relapsed or refractory diffuse large B‐cell lymphoma, CD19 expression by immunohistochemistry alone is not a predictor of response to loncastuximab tesirine
PF Caimi, M Hamadani, C Carlo‐Stella, M Nickaeen, E Jordie, K Utsey, ...
Ejhaem 5 (1), 76-83, 2024
12024
Hierarchical deep compartment modeling: A workflow to leverage machine learning and Bayesian inference for hierarchical pharmacometric modeling
A Elmokadem, M Wiens, T Knab, K Utsey, SP Callisto, D Kirouac
Clinical and Translational Science 17 (10), e70045, 2024
2024
Quantitative Systems Pharmacology Model Predicts Combination Activity of CD19-Targeted Loncastuximab Tesirine Co-Dosed With a CD20/CD3 T-Cell Bispecific (Epcoritamab) in …
Y Li, AK Wilkins, J Davis, T Knab, C Keir, JP Boni
Clinical Lymphoma Myeloma and Leukemia 24, S216, 2024
2024
ABCL-366 Quantitative Systems Pharmacology Model Predicts Combination Activity of CD19-Targeted Loncastuximab Tesirine Co-Dosed With a CD20/CD3 T-Cell Bispecific (Epcoritamab …
Y Li, AK Wilkins, J Davis, T Knab, C Keir, JP Boni
Clinical Lymphoma Myeloma and Leukemia 24, S475, 2024
2024
ABCL-367 Quantitative Systems Pharmacology Modeling of Loncastuximab Tesirine Combined With Mosunetuzumab and Glofitamab Helps Guide Dosing for Patients With DLBCL
Y Li, AK Wilkins, T Knab, C Keir, JP Boni
Clinical Lymphoma Myeloma and Leukemia 24, S475, 2024
2024
Quantitative systems pharmacology (QSP) model to predict combination activity of CD19-targeted antibody drug conjugate (loncastuximab tesirine) co-dosed with a CD20/CD3 T-cell …
JP Boni, Y Li, AK Wilkins, J Davis, T Knab
Journal of Clinical Oncology 42 (16_suppl), e19059-e19059, 2024
2024
Quantitative systems pharmacology modeling of loncastuximab tesirine combined with mosunetuzumab and glofitamab helps guide dosing for patients with DLBCL
Y Li, AK Wilkins, T Knab, JP Boni
Cancer Research 84 (6_Supplement), 875-875, 2024
2024
Dosing regimen optimisation for oseltamivir in immunocompromised paediatric patients with influenza: Extrapolation of efficacy
EB Jordie, L Gibiansky, T Knab, A Lemenuel‐Diot, P Ravva, E Zwanziger, ...
British Journal of Clinical Pharmacology 88 (3), 1189-1201, 2022
2022
Model-Based Closed-Loop Glucose Control in Critical Illness
TD Knab
University of Pittsburgh, 2017
2017
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