| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13221* | 2021 |
| A toxic monomeric conformer of the polyglutamine protein Y Nagai, T Inui, HA Popiel, N Fujikake, K Hasegawa, Y Urade, Y Goto, ... Nature structural & molecular biology 14 (4), 332-340, 2007 | 406 | 2007 |
| Soluble polyglutamine oligomers formed prior to inclusion body formation are cytotoxic T Takahashi, S Kikuchi, S Katada, Y Nagai, M Nishizawa, O Onodera Human molecular genetics 17 (3), 345-356, 2008 | 278 | 2008 |
| Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein PO Bauer, A Goswami, HK Wong, M Okuno, M Kurosawa, M Yamada, ... Nature biotechnology 28 (3), 256-263, 2010 | 271 | 2010 |
| Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones N Fujikake, Y Nagai, HA Popiel, Y Okamoto, M Yamaguchi, T Toda Journal of Biological Chemistry 283 (38), 26188-26197, 2008 | 250 | 2008 |
| Multiple candidate gene analysis identifies α-synuclein as a susceptibility gene for sporadic Parkinson's disease I Mizuta, W Satake, Y Nakabayashi, C Ito, S Suzuki, Y Momose, Y Nagai, ... Human molecular genetics 15 (7), 1151-1158, 2006 | 239 | 2006 |
| Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening Y Nagai, T Tucker, H Ren, DJ Kenan, BS Henderson, JD Keene, ... Journal of Biological Chemistry 275 (14), 10437-10442, 2000 | 223 | 2000 |
| VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease E Miura, T Hasegawa, M Konno, M Suzuki, N Sugeno, N Fujikake, ... Neurobiology of disease 71, 1-13, 2014 | 199 | 2014 |
| Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level T Takeuchi, M Suzuki, N Fujikake, HA Popiel, H Kikuchi, S Futaki, K Wada, ... Proceedings of the National Academy of Sciences 112 (19), E2497-E2506, 2015 | 195 | 2015 |
| Decrease of the D3 dopamine receptor mRNA expression in lymphocytes from patients with Parkinson's disease Y Nagai, S Ueno, Y Saeki, F Soga, M Hirano, T Yanagihara Neurology 46 (3), 791-795, 1996 | 194 | 1996 |
| Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila Y Nagai, N Fujikake, K Ohno, H Higashiyama, HA Popiel, J Rahadian, ... Human molecular genetics 12 (11), 1253-1259, 2003 | 171 | 2003 |
| Parkinson’s disease is a type of amyloidosis featuring accumulation of amyloid fibrils of α-synuclein K Araki, N Yagi, K Aoyama, CJ Choong, H Hayakawa, H Fujimura, ... Proceedings of the National Academy of Sciences 116 (36), 17963-17969, 2019 | 140 | 2019 |
| Regulatory role of RNA chaperone TDP-43 for RNA misfolding and repeat-associated translation in SCA31 T Ishiguro, N Sato, M Ueyama, N Fujikake, C Sellier, A Kanegami, ... Neuron 94 (1), 108-124. e7, 2017 | 125 | 2017 |
| Human peripheral blood lymphocytes express D5 dopamine receptor gene and transcribe the two pseudogenes N Takahashi, Y Nagai, S Ueno, Y Saeki, T Yanagihara FEBS letters 314 (1), 23-25, 1992 | 115 | 1992 |
| Detection of polyglutamine protein oligomers in cells by fluorescence correlation spectroscopy Y Takahashi, Y Okamoto, HA Popiel, N Fujikake, T Toda, M Kinjo, Y Nagai Journal of Biological Chemistry 282 (33), 24039-24048, 2007 | 109 | 2007 |
| Glucocerebrosidase deficiency accelerates the accumulation of proteinase K-resistant α-synuclein and aggravates neurodegeneration in a Drosophila model of … M Suzuki, N Fujikake, T Takeuchi, A Kohyama-Koganeya, K Nakajima, ... Human molecular genetics 24 (23), 6675-6686, 2015 | 101 | 2015 |
| Expression of the D3 dopamine receptor gene and a novel variant transcript generated by alternative splicing in human peripheral blood lymphocytes Y Nagai, S Ueno, Y Saeki, F Soga, T Yanagihara Biochemical and biophysical research communications 194 (1), 368-374, 1993 | 98 | 1993 |
| Knockdown of the Drosophila fused in sarcoma (FUS) homologue causes deficient locomotive behavior and shortening of motoneuron terminal branches H Sasayama, M Shimamura, T Tokuda, Y Azuma, T Yoshida, T Mizuno, ... PLoS One 7 (6), e39483, 2012 | 95 | 2012 |
| Sleep disturbance as a potential modifiable risk factor for Alzheimer’s disease EN Minakawa, K Wada, Y Nagai International journal of molecular sciences 20 (4), 803, 2019 | 92 | 2019 |
| Residual laminin-binding activity and enhanced dystroglycan glycosylation by LARGE in novel model mice to dystroglycanopathy M Kanagawa, A Nishimoto, T Chiyonobu, S Takeda, Y Miyagoe-Suzuki, ... Human molecular genetics 18 (4), 621-631, 2009 | 91 | 2009 |
