Conformational sampling of membranes by Akt controls its activation and inactivation I Lučić, MK Rathinaswamy, L Truebestein, DJ Hamelin, JE Burke, ... Proceedings of the National Academy of Sciences 115 (17), E3940-E3949, 2018 | 89 | 2018 |
Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5 ML Jenkins, JP Margaria, JTB Stariha, RM Hoffmann, JA McPhail, ... Nature Communications 9 (1), 3772, 2018 | 39 | 2018 |
Probing the architecture, dynamics, and inhibition of the PI4KIIIα/TTC7/FAM126 complex GL Dornan, U Dalwadi, DJ Hamelin, RM Hoffmann, CK Yip, JE Burke Journal of molecular biology 430 (18), 3129-3142, 2018 | 28 | 2018 |
The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA-supertype-dependent manner DJ Hamelin, D Fournelle, JC Grenier, J Schockaert, KA Kovalchik, ... Cell systems 13 (2), 143-157. e3, 2022 | 25 | 2022 |
Structural and mechanistic insights into the function of the unconventional class XIV myosin MyoA from Toxoplasma gondii CJ Powell, R Ramaswamy, A Kelsen, DJ Hamelin, DM Warshaw, J Bosch, ... Proceedings of the National Academy of Sciences 115 (45), E10548-E10555, 2018 | 23 | 2018 |
Neolymphostin A is a covalent phosphoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitor that employs an unusual electrophilic vinylogous ester G Castro-Falcón, GS Seiler, O Demir, MK Rathinaswamy, D Hamelin, ... Journal of medicinal chemistry 61 (23), 10463-10472, 2018 | 22 | 2018 |
Probing Protein–Membrane Interactions and Dynamics Using Hydrogen–Deuterium Exchange Mass Spectrometry (HDX-MS) JTB Stariha, RM Hoffmann, DJ Hamelin, JE Burke Protein-Ligand Interactions: Methods and Applications, 465-485, 2021 | 17 | 2021 |
Understanding the constitutive presentation of MHC class I immunopeptidomes in primary tissues P Kubiniok, A Marcu, L Bichmann, L Kuchenbecker, H Schuster, ... Iscience 25 (2), 103768, 2022 | 16 | 2022 |
The juxtamembrane linker in neutral sphingomyelinase-2 functions as an intramolecular allosteric switch that activates the enzyme P Shanbhogue, RM Hoffmann, MV Airola, R Maini, DJ Hamelin, ... Journal of Biological Chemistry 294 (18), 7488-7502, 2019 | 15 | 2019 |
A single discrete Rab5-binding site in phosphoinositide 3-kinase β is required for tumor cell invasion SD Heitz, DJ Hamelin, RM Hoffmann, N Greenberg, G Salloum, Z Erami, ... Journal of Biological Chemistry 294 (12), 4621-4633, 2019 | 13 | 2019 |
MhcVizPipe: A quality control software for rapid assessment of small-to large-scale immunopeptidome datasets KA Kovalchik, Q Ma, L Wessling, F Saab, JD Duquette, P Kubiniok, ... Molecular & Cellular Proteomics 21 (1), 2022 | 12 | 2022 |
Population genomics approaches for genetic characterization of sars-cov-2 lineages F Mostefai, I Gamache, A N'Guessan, J Pelletier, J Huang, CL Murall, ... Frontiers in medicine 9, 207, 2022 | 9 | 2022 |
Immunopeptidomics for Dummies: Detailed Experimental Protocols and Rapid, User-Friendly Visualization of MHC I and II Ligand Datasets with MhcVizPipe KA Kovalchik, L Wessling, F Saab, Q Ma, J Despault, P Kubiniok, ... bioRxiv, 2020.11. 02.360958, 2020 | 6 | 2020 |
Generation of HLA Allele-Specific Spectral Libraries to Identify and Quantify Immunopeptidomes by SWATH/DIA-MS K Kovalchik, D Hamelin, E Caron Clinical Proteomics: Methods and Protocols, 137-147, 2022 | 4 | 2022 |
RHybridFinder: An R package to process immunopeptidomic data for putative hybrid peptide discovery F Saab, DJ Hamelin, Q Ma, KA Kovalchik, I Sirois, P Faridi, C Li, ... STAR protocols 2 (4), 100875, 2021 | 4 | 2021 |
Data-driven approaches for genetic characterization of SARS-CoV-2 lineages F Mostefai, I Gamache, J Huang, A N’Guessan, J Pelletier, ... bioRxiv, 2021.09. 28.462270, 2021 | 3 | 2021 |
The global architecture shaping the heterogeneity and tissue‐dependency of the MHC class I immunopeptidome is evolutionarily conserved P Kubiniok, A Marcu, L Bichmann, L Kuchenbecker, H Schuster, ... bioRxiv, 2020 | 2 | 2020 |
Integrating Machine Learning-Enhanced Immunopeptidomics and SARS-CoV-2 Population-Scale Analyses Unveils Novel Antigenic Features for Next-Generation COVID-19 Vaccines E Caron, K Kovalchik, D Hamelin, P Kubiniok, B Bourdin, F Mostefai, ... | | 2024 |
Characterizing the impact of the mutational landscape of SARS-CoV-2 on epitope presentation and CTL D Hamelin | | 2022 |
Global Analysis of the Mammalian MHC class I Immunopeptidome at the Organism-Wide Scale P Kubiniok, A Marcu, L Bichmann, L Kuchenbecker, H Schuster, ... bioRxiv, 2020.09. 28.317750, 2020 | | 2020 |