Genome editing in iPSC-based neural systems: from disease models to future therapeutic strategies A McTague, G Rossignoli, A Ferrini, S Barral, MA Kurian Frontiers in Genome Editing 3, 630600, 2021 | 43 | 2021 |
Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism J Ng, S Barral, C De La Fuente Barrigon, G Lignani, FA Erdem, ... Science translational medicine 13 (594), eaaw1564, 2021 | 31 | 2021 |
Aromatic l-amino acid decarboxylase deficiency: a patient-derived neuronal model for precision therapies G Rossignoli, K Krämer, E Lugarà, H Alrashidi, S Pope, ... Brain 144 (8), 2443-2456, 2021 | 19 | 2021 |
New variants of AADC deficiency expand the knowledge of enzymatic phenotypes R Montioli, G Bisello, M Dindo, G Rossignoli, CB Voltattorni, M Bertoldi Archives of biochemistry and biophysics 682, 108263, 2020 | 19 | 2020 |
The novel R347g pathogenic mutation of aromatic amino acid decarboxylase provides additional molecular insights into enzyme catalysis and deficiency R Montioli, A Paiardini, MA Kurian, M Dindo, G Rossignoli, SJR Heales, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1864 (6), 676-682, 2016 | 18 | 2016 |
New insights emerging from recent investigations on human group II pyridoxal 5’-phosphate decarboxylases A Paiardini, G Giardina, G Rossignoli, C Borri Voltattorni, M Bertoldi Current Medicinal Chemistry 24 (3), 226-244, 2017 | 17 | 2017 |
Oxygen reactivity with pyridoxal 5′-phosphate enzymes: biochemical implications and functional relevance G Bisello, C Longo, G Rossignoli, RS Phillips, M Bertoldi Amino Acids 52 (8), 1089-1105, 2020 | 16 | 2020 |
Phosphorylation of pyridoxal 5′-phosphate enzymes: an intriguing and neglected topic G Rossignoli, RS Phillips, A Astegno, M Menegazzi, CB Voltattorni, ... Amino acids 50, 205-215, 2018 | 9 | 2018 |
Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation I Zorzan, RM Betto, G Rossignoli, M Arboit, A Drusin, C Corridori, P Martini, ... EMBO reports 24 (4), e55235, 2023 | 8 | 2023 |
Cysteine 180 is a Redox Sensor Modulating the Activity of Human Pyridoxal 5′-Phosphate Histidine Decarboxylase G Rossignoli, A Grottesi, G Bisello, R Montioli, C Borri Voltattorni, ... Biochemistry 57 (44), 6336-6348, 2018 | 4 | 2018 |
TFEB controls syncytiotrophoblast formation and hormone production in placenta M Cesana, G Tufano, F Panariello, N Zampelli, C Soldati, M Mutarelli, ... Cell Death & Differentiation, 1-13, 2024 | 2 | 2024 |
Unraveling the impact of ZZZ3 on the mTOR/ribosome pathway in human embryonic stem cells homeostasis ML Conte, V Lucchino, S Scalise, C Zannino, D Valente, G Rossignoli, ... Stem Cell Reports 19 (5), 729-743, 2024 | 1 | 2024 |
Chemical conversion of human conventional Pluripotent Stem Cells to Trophoblast Stem Cells I Zorzan, RM Betto, G Rossignoli, M Arboit, A Drusin, P Martini, G Martello bioRxiv, 2022.04. 07.487453, 2022 | 1 | 2022 |
Neurodevelopmental and synaptic defects in DNAJC6 parkinsonism, amenable to gene therapy L Abela, L Gianfrancesco, E Tagliatti, G Rossignoli, K Barwick, C Zourray, ... Brain 147 (6), 2023-2037, 2024 | | 2024 |
Active site serine-193 modulates activity of human aromatic amino acid decarboxylase G Bisello, G Rossignoli, S Choi, RS Phillips, M Bertoldi Biochemical and Biophysical Research Communications 679, 6-14, 2023 | | 2023 |
Human DOPA Decarboxylase: Catalysis and Involvement in Pharmacological Treatments for Parkinson’s Disease and Aromatic Amino Acid Decarboxylase Deficiency M Bertoldi, G Rossignoli Pharmaceutical Biocatalysis, 83-100, 2020 | | 2020 |
Human DOPA Decarboxylase: Catalysis and Involvement in Pharmacological Treatments for Parkinson’s Disease and Aromatic Amino Acid Decarboxylase Deficiency B Mariarita, G Rossignoli Pharmaceutical Biocatalysis 1, 2020 | | 2020 |
Aromatic amino acids decarboxylase and histidine decarboxylase: deep functional investigations give insights into pathophysiological mechanisms with possible therapeutic … G Rossignoli | | 2019 |