Deficiency of tenascin-C attenuates liver fibrosis in immune-mediated chronic hepatitis in mice A El-Karef, T Yoshida, EC Gabazza, T Nishioka, H Inada, T Sakakura, ... The Journal of Pathology 211, 86-94, 2007 | 143 | 2007 |
Antioxidant and anti-inflammatory activities of berberine attenuate hepatic fibrosis induced by thioacetamide injection in rats LA Eissa, HI Kenawy, A El-Karef, NM Elsherbiny, KA El-Mihi Chemico-biological interactions 294, 91-100, 2018 | 83 | 2018 |
Naringin attenuates thioacetamide-induced liver fibrosis in rats through modulation of the PI3K/Akt pathway KA El-Mihi, HI Kenawy, A El-Karef, NM Elsherbiny, LA Eissa Life sciences 187, 50-57, 2017 | 74 | 2017 |
Nitrative DNA damage and Oct3/4 expression in urinary bladder cancer with Schistosoma haematobium infection M Ning, T Raynoo, K Hatasu, H Olfat, W Mohamed, EL Tarek, H Yusuke, ... Biochemical and Biophysical Research Communications 414, 344-349, 2011 | 59 | 2011 |
Co-stimulation of human breast cancer cells with transforming growth factor-β and tenascin-C enhances matrix metalloproteinase-9 expression and cancer cell invasion I Kalembeyi, N Rika, I Hiroyasu, A El-Karef, IY Kyoko, S Teruyo, ... International Journal of Experimental Pathology 86, 373-379, 2005 | 57* | 2005 |
Glycyrrhizin ameliorates high fat diet-induced obesity in rats by activating NrF2 pathway NFA El-Magd, M El-Mesery, A El-Karef, MM El-Shishtawy Life Sciences 193, 159-170, 2018 | 52 | 2018 |
Hepatoprotective effect of curcumin on hepatocellular carcinoma through autophagic and apoptic pathways AM Elmansi, AA El-Karef, MM El-Shishtawy, LA Eissa Annals of hepatology 16 (4), 607-618, 2017 | 50 | 2017 |
Protective effects of L-carnosine on CCl4-induced hepatic injury in rats MM Alsheblak, NM Elsherbiny, A El-Karef, MM El-Shishtawy European cytokine network 27, 6-15, 2016 | 49 | 2016 |
Hepatoprotective effect of hesperidin in hepatocellular carcinoma: Involvement of Wnt signaling pathways RA Zaghloul, NM Elsherbiny, HI Kenawy, A El-Karef, LA Eissa, ... Life sciences 185, 114-125, 2017 | 47 | 2017 |
Hepatoprotective effects of glycyrrhizin and omega-3 fatty acids on Nuclear Factor-kappa B pathway in thioacetamide-induced fibrosis in rats AEM Nada, A El.Karef, E Mamdouh, E Laila Egyptian Journal of Basic and Applied Science 2012 (2), 2015 | 46 | 2015 |
Beyond its antioxidant properties: Quercetin targets multiple signalling pathways in hepatocellular carcinoma in rats YA Salama, A El-Karef, AM El Gayyar, N Abdel-Rahman Life Sciences 236, 116933, 2019 | 44 | 2019 |
Protection against nonalcoholic steatohepatitis through targeting IL-18 and IL-1alpha by luteolin N Abu-Elsaad, A El-Karef Pharmacological Reports 71, 688-694, 2019 | 39 | 2019 |
Silymarin and caffeine combination ameliorates experimentally-induced hepatic fibrosis through down-regulation of LPAR1 expression SM Eraky, M El-Mesery, A El-Karef, LA Eissa, AM El-Gayar Biomedicine & Pharmacotherapy 101, 49-57, 2018 | 37 | 2018 |
The vitamin D receptor agonist, calcipotriol, modulates fibrogenic pathways mitigating liver fibrosis in-vivo: an experimental study E Wahsh, N Abu-Elsaad, A El-Karef, T Ibrahim European journal of pharmacology 789, 362-369, 2016 | 36 | 2016 |
Thymoquinone upregulates TRAIL/TRAILR2 expression and attenuates hepatocellular carcinoma in vivo model SA Helmy, M El-Mesery, A El-Karef, LA Eissa, AM El Gayar Life sciences 233, 116673, 2019 | 35 | 2019 |
Yogurt Containing the Probacteria Lactobacillus acidophilus Combined with Natural Antioxidants Mitigates Doxorubicin-Induced Cardiomyopathy in Rats AE Nashwa, M, AE Ahmed, G, A El.Karef, I Tarek, M Journal of Medicinal Food 18 (9), 2015 | 33 | 2015 |
Circulating level of large splice variants of tenascin-C is a marker of piecemeal necrosis activity in patients with chronic hepatitis C T Hideaki, A El.Karef, K Masahiko, K Noriaki, F Naoki, H Shinichiro, ... Liver International 26, 311-318, 2006 | 33 | 2006 |
Expression of large tenascin-C splice variants by hepatic stellate cells/myofibroblasts in chronic hepatitis C A El.Karef, K Masahiko, T Hideaki, I Kazuo, N Tomohiro, F Naoki, ... Journal of Hepatology 46 (4), 664-673, 2007 | 32 | 2007 |
Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model SA Helmy, M El-Mesery, A El-Karef, LA Eissa, AM El Gayar Chemico-biological interactions 279, 84-94, 2018 | 30 | 2018 |
Piceatannol increases the expression of hepatocyte growth factor and IL-10 thereby protecting hepatocytes in thioacetamide-induced liver fibrosis H Abd-Elgawad, N Abu-Elsaad, A El-Karef, T Ibrahim Canadian journal of physiology and pharmacology 94 (7), 779-787, 2016 | 29 | 2016 |