关注
Laura MacConaill
Laura MacConaill
未知所在单位机构
在 dfci.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ...
Nature 483 (7391), 603-607, 2012
82362012
AACR Project GENIE: powering precision medicine through an international consortium
AACR Project Genie Consortium, AACR Project GENIE Consortium, ...
Cancer discovery 7 (8), 818-831, 2017
14512017
Recurrent BRAF mutations in Langerhans cell histiocytosis
G Badalian-Very, JA Vergilio, BA Degar, LE MacConaill, B Brandner, ...
Blood, The Journal of the American Society of Hematology 116 (11), 1919-1923, 2010
13122010
Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling
N Wagle, C Emery, MF Berger, MJ Davis, A Sawyer, P Pochanard, ...
Journal of clinical oncology 29 (22), 3085-3096, 2011
12202011
High-throughput oncogene mutation profiling in human cancer
RK Thomas, AC Baker, RM DeBiasi, W Winckler, T LaFramboise, WM Lin, ...
Nature genetics 39 (3), 347-351, 2007
11752007
MEK1 mutations confer resistance to MEK and B-RAF inhibition
CM Emery, KG Vijayendran, MC Zipser, AM Sawyer, L Niu, JJ Kim, ...
Proceedings of the National Academy of Sciences 106 (48), 20411-20416, 2009
7902009
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations
PK Brastianos, PM Horowitz, S Santagata, RT Jones, A McKenna, G Getz, ...
Nature genetics 45 (3), 285-289, 2013
7112013
High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing
N Wagle, MF Berger, MJ Davis, B Blumenstiel, M DeFelice, P Pochanard, ...
Cancer discovery 2 (1), 82-93, 2012
6512012
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway
CA Lovejoy, W Li, S Reisenweber, S Thongthip, J Bruno, T De Lange, ...
PLoS genetics 8 (7), e1002772, 2012
6452012
Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine
EM Van Allen, N Wagle, P Stojanov, DL Perrin, K Cibulskis, S Marlow, ...
Nature medicine 20 (6), 682-688, 2014
5802014
An oncogene–tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB
J Min, A Zaslavsky, G Fedele, SK McLaughlin, EE Reczek, T De Raedt, ...
Nature medicine 16 (3), 286-294, 2010
4852010
RAS Mutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors
PA Oberholzer, D Kee, P Dziunycz, A Sucker, N Kamsukom, R Jones, ...
Journal of clinical oncology 30 (3), 316-321, 2012
4712012
8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC
N Ahmadiyeh, MM Pomerantz, C Grisanzio, P Herman, L Jia, V Almendro, ...
Proceedings of the National academy of sciences 107 (21), 9742-9746, 2010
4512010
Validation of OncoPanel: a targeted next-generation sequencing assay for the detection of somatic variants in cancer
EP Garcia, A Minkovsky, Y Jia, MD Ducar, P Shivdasani, X Gong, ...
Archives of Pathology and Laboratory Medicine 141 (6), 751-758, 2017
4382017
Institutional implementation of clinical tumor profiling on an unselected cancer population
LM Sholl, K Do, P Shivdasani, E Cerami, AM Dubuc, FC Kuo, EP Garcia, ...
JCI insight 1 (19), 2016
3982016
Profiling critical cancer gene mutations in clinical tumor samples
LE MacConaill, CD Campbell, SM Kehoe, AJ Bass, C Hatton, L Niu, ...
PloS one 4 (11), e7887, 2009
3712009
Oncogenic mutations in cervical cancer: genomic differences between adenocarcinomas and squamous cell carcinomas of the cervix
AA Wright, BE Howitt, AP Myers, SE Dahlberg, E Palescandolo, ...
Cancer 119 (21), 3776-3783, 2013
3112013
Clinical implications of the cancer genome
LE MacConaill, LA Garraway
Journal of Clinical Oncology 28 (35), 5219-5228, 2010
3082010
Differential sensitivity of melanoma cell lines with BRAF V600E mutation to the specific Raf inhibitor PLX4032
JN Søndergaard, R Nazarian, Q Wang, D Guo, T Hsueh, S Mok, ...
Journal of translational medicine 8, 1-11, 2010
2762010
Frameshift events predict anti–PD-1/L1 response in head and neck cancer
GJ Hanna, P Lizotte, M Cavanaugh, FC Kuo, P Shivdasani, A Frieden, ...
JCI insight 3 (4), 2018
2572018
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