Roles of Chk1 in cell biology and cancer therapy Y Zhang, T Hunter International journal of cancer 134 (5), 1013-1023, 2014 | 481 | 2014 |
Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway YW Zhang, DM Otterness, GG Chiang, W Xie, YC Liu, F Mercurio, ... Molecular cell 19 (5), 607-618, 2005 | 315 | 2005 |
CtIP links DNA double-strand break sensing to resection Z You, LZ Shi, Q Zhu, P Wu, YW Zhang, A Basilio, N Tonnu, IM Verma, ... Molecular cell 36 (6), 954-969, 2009 | 279 | 2009 |
The gap junction-independent tumor-suppressing effect of connexin 43 YW Zhang, M Kaneda, I Morita Journal of Biological Chemistry 278 (45), 44852-44856, 2003 | 221 | 2003 |
The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress YW Zhang, J Brognard, C Coughlin, Z You, M Dolled-Filhart, A Aslanian, ... Molecular cell 35 (4), 442-453, 2009 | 211 | 2009 |
Connexin43 suppresses proliferation of osteosarcoma U2OS cells through post-transcriptional regulation of p27 YW Zhang, I Morita, M Ikeda, KW Ma, S Murota Oncogene 20 (31), 4138-4149, 2001 | 189 | 2001 |
Pretreatment with eicosapentaenoic acid prevented hypoxia/reoxygenation-induced abnormality in endothelial gap junctional intercellular communication through inhibiting the … YW Zhang, I Morita, XS Yao, S Murota Prostaglandins, Leukotrienes and Essential Fatty Acids 61 (1), 33-40, 1999 | 177 | 1999 |
A novel route for connexin 43 to inhibit cell proliferation: negative regulation of S-phase kinase-associated protein (Skp 2) YW Zhang, K Nakayama, KI Nakayama, I Morita Cancer research 63 (7), 1623-1630, 2003 | 171 | 2003 |
Inhibitory effects of eicosapentaenoic acid (EPA) on the hypoxia/reoxygenation-induced tyrosine kinase activation in cultured human umbilical vein endothelial cells YW Zhang, XS Yao, S Murota, I Morita Prostaglandins, leukotrienes and essential fatty acids 67 (4), 253-261, 2002 | 158 | 2002 |
Caffeine protects skin from oxidative stress-induced senescence through the activation of autophagy YF Li, SH Ouyang, LF Tu, X Wang, WL Yuan, GE Wang, YP Wu, WJ Duan, ... Theranostics 8 (20), 5713, 2018 | 146 | 2018 |
Targeting the checkpoint kinase Chk1 in cancer therapy C Merry, K Fu, J Wang, IJ Yeh, Y Zhang Cell cycle 9 (2), 279-283, 2010 | 98 | 2010 |
Synthesis, biological function and evaluation of Shikonin in cancer therapy F Wang, X Yao, Y Zhang, J Tang Fitoterapia 134, 329-339, 2019 | 94 | 2019 |
Cancer-associated loss-of-function mutations Implicate DAPK3 as a tumor‐suppressing kinase J Brognard, YW Zhang, LA Puto, T Hunter Cancer research 71 (8), 3152-3161, 2011 | 83 | 2011 |
Screening of anti-hypoxia/reoxygenation agents by an in vitro model. Part 1: Natural inhibitors for protein tyrosine kinase activated by hypoxia/reoxygenation in cultured human … YW Zhang, I Morita, G Shao, XS Yao, S Murota Planta medica 66 (02), 114-118, 2000 | 69 | 2000 |
53BP1 regulates heterochromatin through liquid phase separation L Zhang, X Geng, F Wang, J Tang, Y Ichida, A Sharma, S Jin, M Chen, ... Nature communications 13 (1), 360, 2022 | 66 | 2022 |
The inhibitory effects of ginsenosides on protein tyrosine kinase activated by hypoxia/reoxygenation in cultured human umbilical vein endothelial cells DQ Dou, YW Zhang, L Zhang, YJ Chen, XS Yao Planta medica 67 (01), 19-23, 2001 | 55 | 2001 |
Shikonin inhibits cancer through P21 upregulation and apoptosis induction F Wang, F Mayca Pozo, D Tian, X Geng, X Yao, Y Zhang, J Tang Frontiers in pharmacology 11, 861, 2020 | 50 | 2020 |
UbcH7 regulates 53BP1 stability and DSB repair ZY Han X1, Zhang L1, Chung J1, Mayca Pozo F1, Tran A1, Seachrist DD1 ... Proc Natl Acad Sci U S A 111 (49), 17456-61, 2014 | 48* | 2014 |
Coumarin Analogues from the Citrus grandis (L.) Osbeck and Their Hepatoprotective Activity D Tian, F Wang, M Duan, L Cao, Y Zhang, X Yao, J Tang Journal of Agricultural and Food Chemistry 67 (7), 1937-1947, 2019 | 46 | 2019 |
Coupling cellular localization and function of checkpoint kinase 1 (Chk1) in checkpoints and cell viability J Wang, X Han, X Feng, Z Wang, Y Zhang Journal of Biological Chemistry 287 (30), 25501-25509, 2012 | 46 | 2012 |