The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs YI Zhu, T Tchkonia, T Pirtskhalava, AC Gower, H Ding, N Giorgadze, ... Aging cell 14 (4), 644-658, 2015 | 2058 | 2015 |
Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors YI Zhu, T Tchkonia, H Fuhrmann‐Stroissnigg, HM Dai, YY Ling, MB Stout, ... Aging cell 15 (3), 428-435, 2016 | 956 | 2016 |
JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age M Xu, T Tchkonia, H Ding, M Ogrodnik, ER Lubbers, T Pirtskhalava, ... Proceedings of the National Academy of Sciences 112 (46), E6301-E6310, 2015 | 689 | 2015 |
Targeting senescent cells enhances adipogenesis and metabolic function in old age M Xu, AK Palmer, H Ding, MM Weivoda, T Pirtskhalava, TA White, A Sepe, ... elife 4, e12997, 2015 | 540 | 2015 |
Targeting senescent cells alleviates obesity‐induced metabolic dysfunction AK Palmer, M Xu, YI Zhu, T Pirtskhalava, MM Weivoda, CM Hachfeld, ... Aging cell 18 (3), e12950, 2019 | 473 | 2019 |
Physiological aging: links among adipose tissue dysfunction, diabetes, and frailty MB Stout, JN Justice, BJ Nicklas, JL Kirkland Physiology 32 (1), 9-19, 2017 | 343 | 2017 |
Exercise prevents diet-induced cellular senescence in adipose tissue MJ Schafer, TA White, G Evans, JM Tonne, GC Verzosa, MB Stout, ... Diabetes 65 (6), 1606-1615, 2016 | 320 | 2016 |
Short-term aerobic exercise training in obese humans with type 2 diabetes mellitus improves whole-body insulin sensitivity through gains in peripheral, not hepatic insulin … JJ Winnick, WM Sherman, DL Habash, MB Stout, ML Failla, MA Belury, ... The journal of clinical endocrinology & metabolism 93 (3), 771-778, 2008 | 239 | 2008 |
Cardiac alterations in cancer-induced cachexia in mice M Tian, Y Nishijima, ML Asp, MB Stout, PJ Reiser, MA Belury International journal of oncology 37 (2), 347-353, 2010 | 149 | 2010 |
Liver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles EO List, DE Berryman, K Funk, A Jara, B Kelder, F Wang, MB Stout, X Zhi, ... Endocrinology 155 (5), 1793-1805, 2014 | 143 | 2014 |
Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice MB Stout, T Tchkonia, T Pirtskhalava, AK Palmer, EO List, DE Berryman, ... Aging (Albany NY) 6 (7), 575, 2014 | 121 | 2014 |
17α-Estradiol alleviates age-related metabolic and inflammatory dysfunction in male mice without inducing feminization MB Stout, FJ Steyn, MJ Jurczak, JPG Camporez, YI Zhu, JR Hawse, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2017 | 112 | 2017 |
Time-dependent effects of safflower oil to improve glycemia, inflammation and blood lipids in obese, post-menopausal women with type 2 diabetes: a randomized, double-masked … ML Asp, AL Collene, LE Norris, RM Cole, MB Stout, SY Tang, JC Hsu, ... Clinical nutrition 30 (4), 443-449, 2011 | 108 | 2011 |
TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess L Idrissova, H Malhi, NW Werneburg, NK LeBrasseur, SF Bronk, C Fingas, ... Journal of hepatology 62 (5), 1156-1163, 2015 | 91 | 2015 |
Resilience in aging mice JL Kirkland, MB Stout, F Sierra Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2016 | 86 | 2016 |
Butyrylcholinesterase deficiency promotes adipose tissue growth and hepatic lipid accumulation in male mice on high-fat diet VP Chen, Y Gao, L Geng, MB Stout, MD Jensen, S Brimijoin Endocrinology 157 (8), 3086-3095, 2016 | 56 | 2016 |
Inflammation and the depot‐specific secretome of human preadipocytes Y Zhu, T Tchkonia, MB Stout, N Giorgadze, L Wang, PW Li, ... Obesity 23 (5), 989-999, 2015 | 55 | 2015 |
Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR−/− mice EO List, DE Berryman, Y Ikeno, GB Hubbard, K Funk, R Comisford, ... Aging (Albany NY) 7 (7), 500, 2015 | 51 | 2015 |
Evaluating health span in preclinical models of aging and disease: guidelines, challenges, and opportunities for geroscience DM Huffman, JN Justice, MB Stout, JL Kirkland, N Barzilai, SN Austad Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2016 | 48 | 2016 |
Analysis of DNA modifications in aging research DR Masser, N Hadad, H Porter, MB Stout, A Unnikrishnan, DR Stanford, ... Geroscience 40, 11-29, 2018 | 44 | 2018 |