Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass A Girousse, G Tavernier, C Valle, C Moro, N Mejhert, AL Dinel, ... PLoS biology 11 (2), e1001485, 2013 | 238 | 2013 |
Immune cell Toll-like receptor 4 mediates the development of obesity-and endotoxemia-associated adipose tissue fibrosis IK Vila, PM Badin, MA Marques, L Monbrun, C Lefort, L Mir, K Louche, ... Cell reports 7 (4), 1116-1129, 2014 | 160 | 2014 |
A UBE2O-AMPKα2 axis that promotes tumor initiation and progression offers opportunities for therapy IK Vila, Y Yao, G Kim, W Xia, H Kim, SJ Kim, MK Park, JP Hwang, ... Cancer cell 31 (2), 208-224, 2017 | 123 | 2017 |
High-fat diet-mediated lipotoxicity and insulin resistance is related to impaired lipase expression in mouse skeletal muscle PM Badin, IK Vila, K Louche, A Mairal, MA Marques, V Bourlier, ... Endocrinology 154 (4), 1444-1453, 2013 | 96 | 2013 |
Defective natriuretic peptide receptor signaling in skeletal muscle links obesity to type 2 diabetes M Coué, PM Badin, IK Vila, C Laurens, K Louche, MA Marquès, V Bourlier, ... Diabetes 64 (12), 4033-4045, 2015 | 93 | 2015 |
STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses IK Vila, H Chamma, A Steer, M Saccas, C Taffoni, E Turtoi, LS Reinert, ... Cell metabolism 34 (1), 125-139. e8, 2022 | 85 | 2022 |
PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression MK Park, Y Yao, W Xia, SR Setijono, JH Kim, IK Vila, HH Chiu, Y Wu, ... Nature communications 10 (1), 636, 2019 | 72 | 2019 |
Fatty acids from fat cell lipolysis do not activate an inflammatory response but are stored as triacylglycerols in adipose tissue macrophages S Caspar-Bauguil, CI Kolditz, C Lefort, I Vila, E Mouisel, D Beuzelin, ... Diabetologia 58, 2627-2636, 2015 | 42 | 2015 |
Nucleic acid immunity and DNA damage response: new friends and old foes C Taffoni, A Steer, J Marines, H Chamma, IK Vila, N Laguette Frontiers in immunology 12, 660560, 2021 | 36 | 2021 |
Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation J Guerra, AL Valadao, D Vlachakis, K Polak, IK Vila, C Taffoni, ... Science advances 6 (21), eaax3333, 2020 | 32 | 2020 |
Exercise-like effects by Estrogen-related receptor-gamma in muscle do not prevent insulin resistance in db/db mice PM Badin, IK Vila, DH Sopariwala, V Yadav, S Lorca, K Louche, ER Kim, ... Scientific reports 6 (1), 26442, 2016 | 28 | 2016 |
Activation of STING in the pancreatic tumor microenvironment: a novel therapeutic opportunity H Chamma, IK Vila, C Taffoni, A Turtoi, N Laguette Cancer Letters 538, 215694, 2022 | 21 | 2022 |
A muscle-specific UBE2O/AMPKα2 axis promotes insulin resistance and metabolic syndrome in obesity IK Vila, MK Park, SR Setijono, Y Yao, H Kim, PM Badin, S Choi, V Narkar, ... JCI insight 4 (13), 2019 | 20 | 2019 |
DNA damage repair kinase DNA‐PK and cGAS synergize to induce cancer‐related inflammation in glioblastoma C Taffoni, J Marines, H Chamma, S Guha, M Saccas, A Bouzid, ... The EMBO Journal 42 (7), e111961, 2023 | 18 | 2023 |
Long-term PGC1β overexpression leads to apoptosis, autophagy and muscle wasting DH Sopariwala, V Yadav, PM Badin, N Likhite, M Sheth, S Lorca, IK Vila, ... Scientific reports 7 (1), 10237, 2017 | 14 | 2017 |
Animal models for the study of nucleic acid immunity: novel tools and new perspectives IK Vila, M Fretaud, D Vlachakis, N Laguette, C Langevin Journal of molecular biology 432 (20), 5529-5543, 2020 | 10 | 2020 |
Alternative pathways driven by STING: From innate immunity to lipid metabolism IK Vila, S Guha, J Kalucka, D Olagnier, N Laguette Cytokine & Growth Factor Reviews 68, 54-68, 2022 | 7 | 2022 |
Protocol to induce and assess cGAS-STING pathway activation in vitro H Chamma, S Guha, N Laguette, IK Vila STAR protocols 3 (2), 101384, 2022 | 7 | 2022 |
A new duet in cancer biology: AMPK the typical and UBE2O the atypical IK Vila, SJ Song, MS Song Molecular & Cellular Oncology 4 (3), e1304846, 2017 | 7 | 2017 |
Dietary restriction induces a sexually dimorphic type I interferon response in mice with gene-environment interactions DJ Harney, M Cielesh, GE Roberts, IK Vila, B Viengkhou, MJ Hofer, ... Cell Reports 42 (6), 2023 | 6 | 2023 |