Microwave‐assisted Suzuki coupling reactions with an encapsulated palladium catalyst for batch and continuous‐flow transformations IR Baxendale, CM Griffiths‐Jones, SV Ley, GK Tranmer Chemistry–A European Journal 12 (16), 4407-4416, 2006 | 309 | 2006 |
A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly IR Baxendale, J Deeley, CM Griffiths-Jones, SV Ley, S Saaby, ... Chemical communications, 2566-2568, 2006 | 248 | 2006 |
Fully automated continuous flow synthesis of 4, 5-disubstituted oxazoles M Baumann, IR Baxendale, SV Ley, CD Smith, GK Tranmer Organic letters 8 (23), 5231-5234, 2006 | 161 | 2006 |
Preparation of the neolignan natural product grossamide by a continuous-flow process IR Baxendale, CM Griffiths-Jones, SV Ley, GK Tranmer Synlett 2006 (03), 0427-0430, 2006 | 122 | 2006 |
The boron advantage: the evolution and diversification of boron’s applications in medicinal chemistry K Messner, B Vuong, GK Tranmer Pharmaceuticals 15 (3), 264, 2022 | 74 | 2022 |
Tagged phosphine reagents to assist reaction work-up by phase-switched scavenging using a modular flow reactor CD Smith, IR Baxendale, GK Tranmer, M Baumann, SC Smith, ... Organic & Biomolecular Chemistry 5 (10), 1562-1568, 2007 | 70 | 2007 |
Molybdenum-mediated cleavage reactions of isoxazoline rings fused in bicyclic frameworks GK Tranmer, W Tam Organic Letters 4 (23), 4101-4104, 2002 | 69 | 2002 |
Pharmaceutical strategy and innovation: An academics perspective IR Baxendale, JJ Hayward, SV Ley, GK Tranmer ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 768-788, 2007 | 61 | 2007 |
A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocols IR Baxendale, SV Ley, CD Smith, GK Tranmer Chemical communications, 4835-4837, 2006 | 56 | 2006 |
Intramolecular 1, 3-dipolar cycloadditions of norbornadiene-tethered nitrile oxides C Yip, S Handerson, GK Tranmer, W Tam The Journal of Organic Chemistry 66 (1), 276-286, 2001 | 52 | 2001 |
Synthesis of 2, 3-disubstituted norbornadienes GK Tranmer, C Yip, S Handerson, RW Jordan, W Tam Canadian Journal of Chemistry 78 (5), 527-535, 2000 | 47 | 2000 |
The identification of 4, 7-disubstituted naphthoic acid derivatives as UDP-competitive antagonists of P2Y14 JY Gauthier, M Belley, D Deschênes, JF Fournier, S Gagné, Y Gareau, ... Bioorganic & medicinal chemistry letters 21 (10), 2836-2839, 2011 | 45 | 2011 |
Intramolecular 1, 3-dipolar cycloadditions of norbornadiene-tethered nitrones GK Tranmer, W Tam The Journal of Organic Chemistry 66 (15), 5113-5123, 2001 | 40 | 2001 |
The utilization of copper flow reactors in organic synthesis J Bao, GK Tranmer Chemical Communications 51 (15), 3037-3044, 2015 | 36 | 2015 |
Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series N Lachance, Y Gareau, S Guiral, Z Huang, E Isabel, JP Leclerc, S Léger, ... Bioorganic & medicinal chemistry letters 22 (2), 980-984, 2012 | 36 | 2012 |
Taming the cytokine storm: repurposing montelukast for the attenuation and prophylaxis of severe COVID-19 symptoms N Sanghai, GK Tranmer Drug discovery today 25 (12), 2076-2079, 2020 | 35 | 2020 |
Synthesis and SAR of pyrimidine-based, non-nucleotide P2Y14 receptor antagonists D Guay, C Beaulieu, M Belley, SN Crane, J DeLuca, Y Gareau, M Hamel, ... Bioorganic & medicinal chemistry letters 21 (10), 2832-2835, 2011 | 35 | 2011 |
Continuous flow photochemistry as an enabling synthetic technology: synthesis of substituted-6 (5 H)-phenanthridinones for use as poly (ADP-ribose) polymerase inhibitors Y Fang, GK Tranmer MedChemComm 7 (4), 720-724, 2016 | 30 | 2016 |
Heterocyclic compounds as inhibitors of stearoyl-coenzyme A delta-9 desaturase N LaChance, S Leger, RM Oballa, D Powell, GK Tranmer, E Martins, ... US Patent App. 13/255,922, 2012 | 28 | 2012 |
Hypoxia activated prodrugs: Factors influencing design and development D Liang, G H Miller, G K Tranmer Current medicinal chemistry 22 (37), 4313-4325, 2015 | 24 | 2015 |