Macrophage-derived IL-6 trans-signalling as a novel target in the pathogenesis of bronchopulmonary dysplasia D Hirani, CM Alvira, S Danopoulos, C Milla, M Donato, L Tian, J Mohr, ... European Respiratory Journal 59 (2), 2022 | 75 | 2022 |
Intraperitoneal glucose tolerance test, measurement of lung function, and fixation of the lung to study the impact of obesity and impaired metabolism on pulmonary outcomes K Dinger, J Mohr, C Vohlen, D Hirani, E Hucklenbruch-Rother, ... Journal of Visualized Experiments: Jove, 56685, 2018 | 28 | 2018 |
Strain-dependent effects on lung structure, matrix remodeling, and Stat3/Smad2 signaling in C57BL/6N and C57BL/6J mice after neonatal hyperoxia JP Will, D Hirani, F Thielen, F Klein, C Vohlen, K Dinger, J Dötsch, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2019 | 25 | 2019 |
Elafin treatment rescues EGFR-Klf4 signaling and lung cell survival in ventilated newborn mice MA Alejandre Alcazar, M Kaschwich, R Ertsey, S Preuss, C Milla, ... American Journal of Respiratory Cell and Molecular Biology 59 (5), 623-634, 2018 | 22 | 2018 |
Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life J Selle, K Dinger, V Jentgen, D Zanetti, J Will, T Georgomanolis, C Vohlen, ... Nature Communications 13 (1), 4352, 2022 | 18 | 2022 |
Novel functional role of GH/IGF-I in neonatal lung myofibroblasts and in rat lung growth after intrauterine growth restriction J Nawabi, C Vohlen, K Dinger, C Thangaratnarajah, C Klaudt, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 315 (5 …, 2018 | 15 | 2018 |
Dynamic regulation of GH–IGF1 signaling in injury and recovery in hyperoxia-induced neonatal lung injury C Vohlen, J Mohr, A Fomenko, C Kuiper-Makris, T Grzembke, ... Cells 10 (11), 2947, 2021 | 11 | 2021 |
CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia DV Hirani, F Thielen, S Mansouri, S Danopoulos, C Vohlen, ... Inflammation and Regeneration 43 (1), 52, 2023 | 9 | 2023 |
Intrauterine growth restriction induces skin inflammation, increases TSLP and impairs epidermal barrier function L Polányi, CM Niessen, C Vohlen, J Stinn, T Kretschmer, V Jentgen, ... Journal of Molecular Medicine 98, 279-289, 2020 | 6 | 2020 |
Loss of IL-6 enables lung growth in newborn mice exposed to prolonged hyperoxia D Hirani, K Dinger, J Mohr, C Vohlen, B Darvishan, F Klein, EL Garcia, ... European Respiratory Journal 52 (suppl 62), 2018 | 3 | 2018 |
Novel KLF4-FOXO1 interactome in lung fibroblasts: regulator of myofibroblasts in hyperoxia-induced lung injury D Hirani, M Koch, J Mohr, C Vohlen, S Nayakanti, C Grimm, ... European Respiratory Journal 56 (suppl 64), 2020 | 1 | 2020 |
Loss of IL-6 promotes alveolar progenitor cells and lung growth in newborn mice exposed to mechanical ventilation J Mohr, H Kesler, D Hirani, M Odenthal, J Dötsch, MAA Alcazar European Respiratory Journal 56 (suppl 64), 2020 | 1 | 2020 |
Krüppel-like Factor 4 is a Stat3-Smad2 regulator in ATII cells determining ATII cell fate during lung development and hyperoxia-induced lung injury J Mohr, M Koch, S Danopoulos, L Ebert, N Oikonomou, C Vohlen, ... European Respiratory Journal 54 (suppl 63), 2019 | 1 | 2019 |
Krüppel-like Factor 4 (Klf4) in human and mouse lung development: regulation of ATII cell homeostasis in lungs of newborn mice exposed to HYX J Mohr, M Koch, N Oikonomou, B Schermer, K Dinger, C Vohlen, D Hirani, ... European Respiratory Journal 52 (suppl 62), 2018 | 1 | 2018 |
Krüppel-like factor 4 (Klf4) is a novel regulator of neonatal lung fibroblast homeostasis and reduced in hyperoxia-induced lung injury D Hirani, M Koch, K Dinger, J Mohr, C Vohlen, C Klaudt, J Doetsch, ... European Respiratory Journal 52 (suppl 62), 2018 | 1 | 2018 |
Targeting IL-6 and Endothelin Axis Enables Alveolar Growth in Mechanically Ventilated Newborn Mice DVB Hirani, V Wagde, J Selle, O Klymenko, M Donato, S Preuss, ... C70. FROM BUDS TO BREATH: MECHANISMS AND PATHOGENESIS OF LUNG DEVELOPMENT …, 2024 | | 2024 |
Hemmung der Endothelin 1 (End1)-Interleukin 6 (IL-6) Achse erhält das alveoläre Wachstum bei mechanisch beatmeten neugeborenen Mäusen. D Hirani, C Kuiper-Makris, V Wadge, J Selle, O Klymenko, M Donato, ... Klinische Pädiatrie 236 (02), 0023, 2024 | | 2024 |
Dietary intervention in obese mice protects the offspring from obesity-related inflammation, vascular remodeling, arrest of alveolarization and pulmonary inflamm-aging in a sex … S Krug, J Selle, T Trojan, C Vohlen, D Hirani, O Klymenko, R Janoschek, ... Klinische Pädiatrie 236 (02), 0024, 2024 | | 2024 |
CXCL10 deficiency protects from lung macrophage invasion and enables lung growth during acute injury and recovery in experimental bronchopulmonary dysplasia D Hirani, F Thielen, S Mansouri, S Danopoulos, C Vohlen, ... Zeitschrift für Geburtshilfe und Neonatologie 227 (03), FV078, 2023 | | 2023 |
Blockade des IL-6 trans-Signalwegs schützt vor vaskulärem und bronchialem Umbau in experimenteller BPD C Bartz, D Hirani, I Mizikóva, J Selle, C Vohlen, R Wilke, C Kuiper-Makris, ... Zeitschrift für Geburtshilfe und Neonatologie 227 (03), FV079, 2023 | | 2023 |