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William Brad Ruzicka
William Brad Ruzicka
Assistant Professor of Psychiatry, Harvard Medical School
在 mclean.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability
L Tremolizzo, G Carboni, WB Ruzicka, CP Mitchell, I Sugaya, P Tueting, ...
Proceedings of the National Academy of Sciences 99 (26), 17095-17100, 2002
4662002
Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection
WB Ruzicka, A Zhubi, M Veldic, DR Grayson, E Costa, A Guidotti
Molecular psychiatry 12 (4), 385-397, 2007
2012007
S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis
A Guidotti, W Ruzicka, DR Grayson, M Veldic, G Pinna, JM Davis, E Costa
Neuroreport 18 (1), 57-60, 2007
1212007
Reviewing the role of DNA (cytosine-5) methyltransferase overexpression in the cortical GABAergic dysfunction associated with psychosis vulnerability
E Dong, DR Grayson, A Guidotti, W Ruzicka, M Veldic, E Costa
Epigenetics 2 (1), 29-36, 2007
1052007
Circuit-and diagnosis-specific DNA methylation changes at γ-aminobutyric acid–related genes in postmortem human hippocampus in schizophrenia and bipolar disorder
WB Ruzicka, S Subburaju, FM Benes
JAMA psychiatry 72 (6), 541-551, 2015
1002015
DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients
E Dong, WB Ruzicka, DR Grayson, A Guidotti
Schizophrenia research 167 (1-3), 35-41, 2015
972015
GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability
E Costa, Y Chen, E Dong, DR Grayson, M Kundakovic, E Maloku, ...
Expert Review of Neurotherapeutics 9 (1), 87-98, 2009
782009
Single-cell dissection of schizophrenia reveals neurodevelopmental-synaptic link and transcriptional resilience associated cellular state
B Ruzicka, S Mohammadi, J Davila-Velderrain, S Subburaju, R Tso, ...
Biological psychiatry 89 (9), S106, 2021
572021
Epigenetic targets in GABAergic neurons to treat schizophrenia
E Costa, E Dong, DR Grayson, WB Ruzicka, MV Simonini, M Veldic, ...
Advances in pharmacology 54, 95-117, 2006
412006
Fifty years of research on schizophrenia: the ascendance of the glutamatergic synapse
JT Coyle, WB Ruzicka, DT Balu
American Journal of Psychiatry 177 (12), 1119-1128, 2020
402020
Toward dissecting the etiology of schizophrenia: HDAC1 and DAXX regulate GAD67 expression in an in vitro hippocampal GABA neuron model
S Subburaju, AJ Coleman, WB Ruzicka, FM Benes
Translational Psychiatry 6 (1), e723-e723, 2016
202016
Epigenetic mechanisms in the pathophysiology of psychotic disorders
WB Ruzicka
Harvard review of psychiatry 23 (3), 212-222, 2015
142015
Single-cell anatomical analysis of human hippocampus and entorhinal cortex uncovers early-stage molecular pathology in Alzheimer’s disease
J Davila-Velderrain, H Mathys, S Mohammadi, B Ruzicka, X Jiang, A Ng, ...
bioRxiv, 2021.07. 01.450715, 2021
122021
Variability of DNA methylation within schizophrenia risk loci across subregions of human hippocampus
WB Ruzicka, S Subburaju, FM Benes
Genes 8 (5), 143, 2017
112017
Single-cell multi-cohort dissection of the schizophrenia transcriptome
WB Ruzicka, S Mohammadi, JF Fullard, J Davila-Velderrain, S Subburaju, ...
medRxiv, 2022.08. 31.22279406, 2022
82022
Systematic investigation of allelic regulatory activity of schizophrenia-associated common variants
JC McAfee, S Lee, J Lee, JL Bell, O Krupa, J Davis, K Insigne, ML Bond, ...
Cell Genomics 3 (10), 2023
72023
Location matters: distinct DNA methylation patterns in GABAergic interneuronal populations from separate microcircuits within the human hippocampus
WB Ruzicka, S Subburaju, JT Coyle, FM Benes
Human Molecular Genetics 27 (2), 254-265, 2018
72018
Epigenetic regulation of glutamic acid decarboxylase 67 in a hippocampal circuit
S Subburaju, AJ Coleman, MG Cunningham, WB Ruzicka, FM Benes
Cerebral Cortex 27 (11), 5284-5293, 2017
72017
643. Sustained Improvement in Mood after 3 Days of Low Field Magnetic Stimulation in Subjects with Bipolar Depression
M Rohan, R Yamamoto, W Ruzicka, M Copersino, S Fuller, M Murphy, ...
Biological Psychiatry 81 (10), S260-S261, 2017
12017
P. 3. d. 067 Potential and direct methylation of 5-HT receptors in treatment resistant schizophrenia
A Bani-Fatemi, WB Ruzicka, VV De Luca
European Neuropsychopharmacology, S562, 2014
12014
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