An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability L Tremolizzo, G Carboni, WB Ruzicka, CP Mitchell, I Sugaya, P Tueting, ... Proceedings of the National Academy of Sciences 99 (26), 17095-17100, 2002 | 468 | 2002 |
Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection WB Ruzicka, A Zhubi, M Veldic, DR Grayson, E Costa, A Guidotti Molecular psychiatry 12 (4), 385-397, 2007 | 200 | 2007 |
S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis A Guidotti, W Ruzicka, DR Grayson, M Veldic, G Pinna, JM Davis, E Costa Neuroreport 18 (1), 57-60, 2007 | 123 | 2007 |
Circuit-and diagnosis-specific DNA methylation changes at γ-aminobutyric acid–related genes in postmortem human hippocampus in schizophrenia and bipolar disorder WB Ruzicka, S Subburaju, FM Benes JAMA psychiatry 72 (6), 541-551, 2015 | 105 | 2015 |
Reviewing the role of DNA (cytosine-5) methyltransferase overexpression in the cortical GABAergic dysfunction associated with psychosis vulnerability E Dong, DR Grayson, A Guidotti, W Ruzicka, M Veldic, E Costa Epigenetics 2 (1), 29-36, 2007 | 105 | 2007 |
DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients E Dong, WB Ruzicka, DR Grayson, A Guidotti Schizophrenia research 167 (1-3), 35-41, 2015 | 101 | 2015 |
GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability E Costa, Y Chen, E Dong, DR Grayson, M Kundakovic, E Maloku, ... Expert Review of Neurotherapeutics 9 (1), 87-98, 2009 | 79 | 2009 |
Single-cell dissection of schizophrenia reveals neurodevelopmental-synaptic link and transcriptional resilience associated cellular state B Ruzicka, S Mohammadi, J Davila-Velderrain, S Subburaju, R Tso, ... Biological psychiatry 89 (9), S106, 2021 | 59 | 2021 |
Fifty years of research on schizophrenia: the ascendance of the glutamatergic synapse JT Coyle, WB Ruzicka, DT Balu American Journal of Psychiatry 177 (12), 1119-1128, 2020 | 55 | 2020 |
Epigenetic targets in GABAergic neurons to treat schizophrenia E Costa, E Dong, DR Grayson, WB Ruzicka, MV Simonini, M Veldic, ... Advances in pharmacology 54, 95-117, 2006 | 41 | 2006 |
Single-cell multi-cohort dissection of the schizophrenia transcriptome WB Ruzicka, S Mohammadi, JF Fullard, J Davila-Velderrain, S Subburaju, ... Science 384 (6698), eadg5136, 2024 | 21 | 2024 |
Toward dissecting the etiology of schizophrenia: HDAC1 and DAXX regulate GAD67 expression in an in vitro hippocampal GABA neuron model S Subburaju, AJ Coleman, WB Ruzicka, FM Benes Translational Psychiatry 6 (1), e723-e723, 2016 | 20 | 2016 |
Systematic investigation of allelic regulatory activity of schizophrenia-associated common variants JC McAfee, S Lee, J Lee, JL Bell, O Krupa, J Davis, K Insigne, ML Bond, ... Cell Genomics 3 (10), 2023 | 17 | 2023 |
Single-cell anatomical analysis of human hippocampus and entorhinal cortex uncovers early-stage molecular pathology in Alzheimer’s disease J Davila-Velderrain, H Mathys, S Mohammadi, B Ruzicka, X Jiang, A Ng, ... bioRxiv, 2021.07. 01.450715, 2021 | 15 | 2021 |
Epigenetic mechanisms in the pathophysiology of psychotic disorders WB Ruzicka Harvard review of psychiatry 23 (3), 212-222, 2015 | 15 | 2015 |
Variability of DNA methylation within schizophrenia risk loci across subregions of human hippocampus WB Ruzicka, S Subburaju, FM Benes Genes 8 (5), 143, 2017 | 12 | 2017 |
Location matters: distinct DNA methylation patterns in GABAergic interneuronal populations from separate microcircuits within the human hippocampus WB Ruzicka, S Subburaju, JT Coyle, FM Benes Human Molecular Genetics 27 (2), 254-265, 2018 | 7 | 2018 |
Epigenetic regulation of glutamic acid decarboxylase 67 in a hippocampal circuit S Subburaju, AJ Coleman, MG Cunningham, WB Ruzicka, FM Benes Cerebral Cortex 27 (11), 5284-5293, 2017 | 7 | 2017 |
The single-cell opioid responses in the context of HIV (SCORCH) consortium SA Ament, RR Campbell, MK Lobo, JP Receveur, K Agrawal, A Borjabad, ... Molecular Psychiatry, 1-12, 2024 | 1 | 2024 |
643. Sustained Improvement in Mood after 3 Days of Low Field Magnetic Stimulation in Subjects with Bipolar Depression M Rohan, R Yamamoto, W Ruzicka, M Copersino, S Fuller, M Murphy, ... Biological Psychiatry 81 (10), S260-S261, 2017 | 1 | 2017 |