Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia PX Xu, J Adams, H Peters, MC Brown, S Heaney, R Maas Nature genetics 23 (1), 113-117, 1999 | 802 | 1999 |
SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1–SIX1–DNA complexes RG Ruf, PX Xu, D Silvius, EA Otto, F Beekmann, UT Muerb, S Kumar, ... Proceedings of the National Academy of Sciences 101 (21), 8090-8095, 2004 | 507 | 2004 |
Six1 is required for the early organogenesis of mammalian kidney PX Xu, W Zheng, L Huang, P Maire, C Laclef, D Silvius Oxford University Press for The Company of Biologists Limited 130 (14), 3085 …, 2003 | 418 | 2003 |
The role of Six1 in mammalian auditory system development W Zheng, L Huang, ZB Wei, D Silvius, B Tang, PX Xu Oxford University Press for The Company of Biologists Limited 130 (17), 3989 …, 2003 | 398 | 2003 |
Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode PX Xu, I Woo, H Her, DR Beier, RL Maas Development 124 (1), 219-231, 1997 | 380 | 1997 |
Eya1 is required for the morphogenesis of mammalian thymus, parathyroid and thyroid PX Xu, W Zheng, C Laclef, P Maire, RL Maas, H Peters, X Xu Oxford University Press for The Company of Biologists Limited 129 (13), 3033 …, 2002 | 321 | 2002 |
Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes D Zou, D Silvius, B Fritzsch, PX Xu Oxford University Press for The Company of Biologists Limited 131 (22), 5561 …, 2004 | 273 | 2004 |
Eya1-Six1 interaction is sufficient to induce hair cell fate in the cochlea by activating Atoh1 expression in cooperation with Sox2 M Ahmed, EYM Wong, J Sun, J Xu, F Wang, PX Xu Developmental cell 22 (2), 377-390, 2012 | 258 | 2012 |
Six1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype R Grifone, C Laclef, F Spitz, S Lopez, J Demignon, JE Guidotti, ... Molecular and cellular biology, 2004 | 230 | 2004 |
Transcription factor SIX5 is mutated in patients with branchio-oto-renal syndrome BE Hoskins, CH Cramer, D Silvius, D Zou, RM Raymond, DJ Orten, ... The American Journal of Human Genetics 80 (4), 800-804, 2007 | 227 | 2007 |
Regulation of Pax6 expression is conserved between mice and flies PX Xu, X Zhang, S Heaney, A Yoon, AM Michelson, RL Maas Development 126 (2), 383-395, 1999 | 217 | 1999 |
Mouse Eya genes are expressed during limb tendon development and encode a transcriptional activation function PX Xu, J Cheng, JA Epstein, RL Maas Proceedings of the National Academy of Sciences 94 (22), 11974-11979, 1997 | 203 | 1997 |
Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs, and their vasculature Y Rinkevich, T Mori, D Sahoo, PX Xu, JR Bermingham Jr, IL Weissman Nature cell biology 14 (12), 1251-1260, 2012 | 198 | 2012 |
Eya1 and Eya2 proteins are required for hypaxial somitic myogenesis in the mouse embryo R Grifone, J Demignon, J Giordani, C Niro, E Souil, F Bertin, C Laclef, ... Developmental biology 302 (2), 602-616, 2007 | 190 | 2007 |
Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation M Bouchard, D de Caprona, M Busslinger, P Xu, B Fritzsch BMC developmental biology 10, 1-17, 2010 | 179 | 2010 |
EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear M Ahmed, J Xu, PX Xu Development 139 (11), 1965-1977, 2012 | 153 | 2012 |
Patterning of the third pharyngeal pouch into thymus/parathyroid by Six and Eya1 D Zou, D Silvius, J Davenport, R Grifone, P Maire, PX Xu Developmental biology 293 (2), 499-512, 2006 | 153 | 2006 |
Eya1 acts as a critical regulator for specifying the metanephric mesenchyme G Sajithlal, D Zou, D Silvius, PX Xu Developmental biology 284 (2), 323-336, 2005 | 152 | 2005 |
Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis J Xu, EYM Wong, C Cheng, J Li, MTK Sharkar, CY Xu, B Chen, J Sun, ... Developmental cell 31 (4), 434-447, 2014 | 133 | 2014 |
Molecular effects of Eya1 domain mutations causing organ defects in BOR syndrome C Buller, X Xu, V Marquis, R Schwanke, PX Xu Human molecular genetics 10 (24), 2775-2781, 2001 | 125 | 2001 |