Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia P Ranganathan, X Yu, C Na, R Santhanam, S Shacham, M Kauffman, ... Blood, The Journal of the American Society of Hematology 120 (9), 1765-1773, 2012 | 229 | 2012 |
Regulation of acute graft-versus-host disease by microRNA-155 P Ranganathan, CEA Heaphy, S Costinean, N Stauffer, C Na, ... Blood, The Journal of the American Society of Hematology 119 (20), 4786-4797, 2012 | 160 | 2012 |
Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies ZA Hing, HYJ Fung, P Ranganathan, S Mitchell, D El-Gamal, JA Woyach, ... Leukemia 30 (12), 2364-2372, 2016 | 138 | 2016 |
Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality A Saha, RS O’Connor, G Thangavelu, SB Lovitch, DB Dandamudi, ... The Journal of clinical investigation 126 (7), 2642-2660, 2016 | 96 | 2016 |
XPO1 inhibition using selinexor synergizes with chemotherapy in acute myeloid leukemia by targeting DNA repair and restoring topoisomerase IIα to the nucleus P Ranganathan, T Kashyap, X Yu, X Meng, TH Lai, B McNeil, ... Clinical Cancer Research 22 (24), 6142-6152, 2016 | 87 | 2016 |
miR-146b antagomir–treated human Tregs acquire increased GVHD inhibitory potency Y Lu, KL Hippen, AL Lemire, J Gu, W Wang, X Ni, P Ranganathan, ... Blood, The Journal of the American Society of Hematology 128 (10), 1424-1435, 2016 | 65 | 2016 |
Decitabine priming enhances the antileukemic effects of exportin 1 (XPO1) selective inhibitor selinexor in acute myeloid leukemia P Ranganathan, X Yu, R Santhanam, J Hofstetter, A Walker, K Walsh, ... Blood, The Journal of the American Society of Hematology 125 (17), 2689-2692, 2015 | 65 | 2015 |
Complement-mediated thrombotic microangiopathy as a link between endothelial damage and steroid-refractory GVHD SA Wall, Q Zhao, M Yearsley, L Blower, A Agyeman, P Ranganathan, ... Blood advances 2 (20), 2619-2628, 2018 | 56 | 2018 |
Implications of the miR-10 family in chemotherapy response of NPM1-mutated AML V Havelange, P Ranganathan, S Geyer, D Nicolet, X Huang, X Yu, ... Blood, The Journal of the American Society of Hematology 123 (15), 2412-2415, 2014 | 53 | 2014 |
Serum miR-29a is upregulated in acute graft-versus-host disease and activates dendritic cells through TLR binding P Ranganathan, A Ngankeu, NC Zitzer, PP Leoncini, X Yu, L Casadei, ... The Journal of Immunology 198 (6), 2500-2512, 2017 | 47 | 2017 |
Determinant roles of dendritic cell-expressed Notch Delta-like and Jagged ligands on anti-tumor T cell immunity EE Tchekneva, MUL Goruganthu, RV Uzhachenko, PL Thomas, ... Journal for immunotherapy of cancer 7, 1-17, 2019 | 45 | 2019 |
Selinexor in combination with decitabine in patients with acute myeloid leukemia: results from a phase 1 study B Bhatnagar, Q Zhao, AS Mims, S Vasu, GK Behbehani, K Larkin, ... Leukemia & lymphoma 61 (2), 387-396, 2020 | 41 | 2020 |
Knockout of both miR-15/16 loci induces acute myeloid leukemia F Lovat, M Fassan, D Sacchi, P Ranganathan, A Palamarchuk, M Bill, ... Proceedings of the National Academy of Sciences 115 (51), 13069-13074, 2018 | 40 | 2018 |
PRMT5 regulates T cell interferon response and is a target for acute graft-versus-host disease KJ Snyder, NC Zitzer, Y Gao, HK Choe, NE Sell, L Neidemire-Colley, ... JCI insight 5 (8), 2020 | 36 | 2020 |
Somatic hypermutation of TCR γ V genes in the sandbar shark H Chen, H Bernstein, P Ranganathan, SF Schluter Developmental & Comparative Immunology 37 (1), 176-183, 2012 | 35 | 2012 |
MicroRNA-155 modulates acute graft-versus-host disease by impacting T cell expansion, migration, and effector function NC Zitzer, K Snyder, X Meng, PA Taylor, YA Efebera, SM Devine, ... The Journal of Immunology 200 (12), 4170-4179, 2018 | 30 | 2018 |
EGFL7 antagonizes NOTCH signaling and represents a novel therapeutic target in acute myeloid leukemia M Bill, A Pathmanathan, M Karunasiri, C Shen, MH Burke, ... Clinical Cancer Research 26 (3), 669-678, 2020 | 23 | 2020 |
Discovery and functional implications of a miR-29b-1/miR-29a cluster polymorphism in acute myeloid leukemia A Ngankeu, P Ranganathan, V Havelange, D Nicolet, S Volinia, ... Oncotarget 9 (4), 4354, 2018 | 16 | 2018 |
Dissection of the major hematopoietic quantitative trait locus in chromosome 6q23. 3 identifies miR-3662 as a player in hematopoiesis and acute myeloid leukemia SE Maharry, CJ Walker, S Liyanarachchi, S Mehta, M Patel, MA Bainazar, ... Cancer discovery 6 (9), 1036-1051, 2016 | 16 | 2016 |
Autoantibodies to the δ-opioid receptor function as opioid agonists and display immunomodulatory activity P Ranganathan, H Chen, MK Adelman, SF Schluter Journal of neuroimmunology 217 (1-2), 65-73, 2009 | 15 | 2009 |