| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13289* | 2021 |
| α-Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models AA Cooper, AD Gitler, A Cashikar, CM Haynes, KJ Hill, B Bhullar, K Liu, ... Science 313 (5785), 324-328, 2006 | 1713 | 2006 |
| Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation AM Nargund, MW Pellegrino, CJ Fiorese, BM Baker, CM Haynes Science 337 (6094), 587-590, 2012 | 1005 | 2012 |
| Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death CM Haynes, EA Titus, AA Cooper Molecular cell 15 (5), 767-776, 2004 | 721 | 2004 |
| ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans CM Haynes, K Petrova, C Benedetti, Y Yang, D Ron Developmental cell 13 (4), 467-480, 2007 | 633 | 2007 |
| The mitochondrial UPR–protecting organelle protein homeostasis CM Haynes, D Ron Journal of cell science 123 (22), 3849-3855, 2010 | 596 | 2010 |
| The transcription factor ATF5 mediates a mammalian mitochondrial UPR CJ Fiorese, AM Schulz, YF Lin, N Rosin, MW Pellegrino, CM Haynes Current biology 26 (15), 2037-2043, 2016 | 571 | 2016 |
| The mitochondrial UPR: mechanisms, physiological functions and implications in ageing T Shpilka, CM Haynes Nature reviews Molecular cell biology 19 (2), 109-120, 2018 | 564 | 2018 |
| The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376. 7 in C. elegans CM Haynes, Y Yang, SP Blais, TA Neubert, D Ron Molecular cell 37 (4), 529-540, 2010 | 557 | 2010 |
| A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging M Mohrin, J Shin, Y Liu, K Brown, H Luo, Y Xi, CM Haynes, D Chen Science 347 (6228), 1374-1377, 2015 | 478 | 2015 |
| Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes O Florey, SE Kim, CP Sandoval, CM Haynes, M Overholtzer Nature cell biology 13 (11), 1335-1343, 2011 | 461 | 2011 |
| UPRmt regulation and output: a stress response mediated by mitochondrial-nuclear communication A Melber, CM Haynes Cell research 28 (3), 281-295, 2018 | 433 | 2018 |
| Mitochondrial and nuclear accumulation of the transcription factor ATFS-1 promotes OXPHOS recovery during the UPRmt AM Nargund, CJ Fiorese, MW Pellegrino, P Deng, CM Haynes Molecular cell 58 (1), 123-133, 2015 | 429 | 2015 |
| Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response C Benedetti, CM Haynes, Y Yang, HP Harding, D Ron Genetics 174 (1), 229-239, 2006 | 408 | 2006 |
| Signaling the mitochondrial unfolded protein response MW Pellegrino, AM Nargund, CM Haynes Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (2), 410-416, 2013 | 405 | 2013 |
| Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2 BM Baker, AM Nargund, T Sun, CM Haynes PLoS genetics 8 (6), e1002760, 2012 | 350 | 2012 |
| Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection MW Pellegrino, AM Nargund, NV Kirienko, R Gillis, CJ Fiorese, ... Nature 516 (7531), 414-417, 2014 | 347 | 2014 |
| Post-2020 biodiversity targets need to embrace climate change A Arneth, YJ Shin, P Leadley, C Rondinini, E Bukvareva, M Kolb, ... Proceedings of the National Academy of Sciences 117 (49), 30882-30891, 2020 | 311* | 2020 |
| Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response YF Lin, AM Schulz, MW Pellegrino, Y Lu, S Shaham, CM Haynes Nature 533 (7603), 416-419, 2016 | 289 | 2016 |
| Mitochondrial protein quality control during biogenesis and aging BM Baker, CM Haynes Trends in biochemical sciences 36 (5), 254-261, 2011 | 227 | 2011 |
