The metabolite BH4 controls T cell proliferation in autoimmunity and cancer SJF Cronin, C Seehus, A Weidinger, S Talbot, S Reissig, M Seifert, ... Nature 563 (7732), 564-568, 2018 | 208 | 2018 |
Identification of ALK in Thinness M Orthofer, A Valsesia, R Mägi, QP Wang, J Kaczanowska, I Kozieradzki, ... Cell 181 (6), 1246-1262. e22, 2020 | 87 | 2020 |
Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome P Tsvetkov, ML Mendillo, J Zhao, JE Carette, PH Merrill, D Cikes, ... elife 4, e08467, 2015 | 86 | 2015 |
The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception V Nagy, T Cole, C Van Campenhout, TM Khoung, C Leung, S Vermeiren, ... Cell Cycle 14 (12), 1799-1808, 2015 | 52 | 2015 |
ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF-and IFNγ-driven immunopathology R Gawish, P Starkl, L Pimenov, A Hladik, K Lakovits, F Oberndorfer, ... Elife 11, e74623, 2022 | 47 | 2022 |
Sigma-1 receptor inhibition reduces neuropathic pain induced by partial sciatic nerve transection in mice by opioid-dependent and-independent mechanisms I Bravo-Caparrós, G Perazzoli, S Yeste, D Cikes, JM Baeyens, EJ Cobos, ... Frontiers in pharmacology 10, 613, 2019 | 47 | 2019 |
Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice MA Tejada, A Montilla-García, SJ Cronin, D Cikes, C Sánchez-Fernández, ... Proceedings of the National Academy of Sciences 114 (31), 8396-8401, 2017 | 40 | 2017 |
Deletion of Tis7 protects mice from high-fat diet-induced weight gain and blunts the intestinal adaptive response postresection C Yu, S Jiang, J Lu, CC Coughlin, Y Wang, EA Swietlicki, L Wang, I Vietor, ... The Journal of nutrition 140 (11), 1907-1914, 2010 | 24 | 2010 |
HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases M Kogler, L Tortola, GL Negri, A Leopoldi, AM El-Naggar, S Mereiter, ... Cancer research 80 (14), 3009-3022, 2020 | 22 | 2020 |
The HUSH complex controls brain architecture and protocadherin fidelity A Hagelkruys, M Horrer, J Taubenschmid-Stowers, A Kavirayani, ... Science advances 8 (44), eabo7247, 2022 | 12 | 2022 |
Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability CS Olie, E van der Wal, D Cikes, L Maton, JC de Greef, IH Lin, YF Chen, ... Scientific reports 10 (1), 17621, 2020 | 8 | 2020 |
PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing D Cikes, K Elsayad, E Sezgin, E Koitai, F Torma, M Orthofer, R Yarwood, ... Nature Metabolism 5 (3), 495-515, 2023 | 7 | 2023 |
Brillouin light scattering anisotropy microscopy for imaging the viscoelastic anisotropy in living cells H Keshmiri, D Cikes, M Samalova, L Schindler, LM Appel, M Urbanek, ... Nature Photonics, 2024 | 5* | 2024 |
Gpcpd1-GPC metabolic pathway is dysfunctional in aging and its deficiency severely perturbs glucose metabolism D Cikes, M Leutner, SJF Cronin, M Novatchkova, L Pfleger, R Klepochová, ... Nature Aging, 2024 | 5* | 2024 |
The negative adipogenesis regulator Dlk1 is transcriptionally regulated by Ifrd1 (TIS7) and translationally by its orthologue Ifrd2 (SKMc15) I Vietor, D Cikes, K Piironen, T Vasakou, D Heimdörfer, R Gstir, ... Elife 12, e88350, 2023 | 5* | 2023 |
Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons SJF Cronin, W Yu, A Hale, S Licht-Mayer, MJ Crabtree, JA Korecka, ... bioRxiv, 2023 | 2 | 2023 |
Pseudorabies virus hijacks DDX3X, initiating an addictive “mad itch” and immune suppression, to facilitate viral spread SJF Cronin, MA Tejada, R Song, K Laval, D Cikes, M Ji, A Brai, ... bioRxiv, 2023 | 1 | 2023 |
Neuropeptide Neuromedin B does not alter body weight and glucose homeostasis nor does it act as an insulin-releasing peptide D Cikes, P Atanes, SJF Cronin, A Hagelkrüys, GC Huang, SJ Persaud, ... Scientific Reports 12 (1), 9383, 2022 | 1 | 2022 |
A conserved role for PCYT2-regulated lipid biosynthesis in muscle health and ageing JM Penninger, D Cikes NATURE METABOLISM 5 (3), 368-369, 2023 | | 2023 |
Research briefing JM Penninger, D Cikes Nature 5, 368-369, 2023 | | 2023 |