Human TUBB3 Mutations Perturb Microtubule Dynamics, Kinesin Interactions, and Axon Guidance MA Tischfield, HN Baris, C Wu, G Rudolph, L Van Maldergem, W He, ... Cell 140 (1), 74-87, 2010 | 635 | 2010 |
Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle ML Gupta Jr, P Carvalho, DM Roof, D Pellman Nature cell biology 8 (9), 913-923, 2006 | 406 | 2006 |
Mutations in TUBB8 and Human Oocyte Meiotic Arrest R Feng, Q Sang, Y Kuang, X Sun, Z Yan, S Zhang, J Shi, G Tian, ... New England Journal of Medicine 374 (3), 223-232, 2016 | 282 | 2016 |
Cell cycle control of kinesin-mediated transport of Bik1 (CLIP-170) regulates microtubule stability and dynein activation P Carvalho, ML Gupta Jr, MA Hoyt, D Pellman Developmental cell 6 (6), 815-829, 2004 | 281 | 2004 |
Phenotypic spectrum of the tubulin-related disorders and functional implications of disease-causing mutations MA Tischfield, GY Cederquist, ML Gupta Jr, EC Engle Current opinion in genetics & development 21 (3), 286-294, 2011 | 234 | 2011 |
Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome KM Austin, ML Gupta Jr, SA Coats, A Tulpule, G Mostoslavsky, AB Balazs, ... The Journal of clinical investigation 118 (4), 1511-1518, 2008 | 169 | 2008 |
Epothilone and paclitaxel: unexpected differences in promoting the assembly and stabilization of yeast microtubules CJ Bode, ML Gupta Jr, EA Reiff, KA Suprenant, GI Georg, RH Himes Biochemistry 41 (12), 3870-3874, 2002 | 157 | 2002 |
Mechanisms underlying the dual-mode regulation of microtubule dynamics by Kip3/kinesin-8 X Su, W Qiu, ML Gupta Jr, JB Pereira-Leal, SL Reck-Peterson, D Pellman Molecular cell 43 (5), 751-763, 2011 | 148 | 2011 |
An inherited TUBB2B mutation alters a kinesin-binding site and causes polymicrogyria, CFEOM and axon dysinnervation GY Cederquist, A Luchniak, MA Tischfield, M Peeva, Y Song, ... Human molecular genetics 21 (26), 5484-5499, 2012 | 132 | 2012 |
Understanding tubulin–Taxol interactions: mutations that impart Taxol binding to yeast tubulin ML Gupta Jr, CJ Bode, GI Georg, RH Himes Proceedings of the National Academy of Sciences 100 (11), 6394-6397, 2003 | 131 | 2003 |
Stabilization of tubulin by deuterium oxide G Chakrabarti, S Kim, ML Gupta Jr, JS Barton, RH Himes Biochemistry 38 (10), 3067-3072, 1999 | 90 | 1999 |
β-Tubulin C354 mutations that severely decrease microtubule dynamics do not prevent nuclear migration in yeast ML Gupta Jr, CJ Bode, DA Thrower, CG Pearson, KA Suprenant, ... Molecular biology of the cell 13 (8), 2919-2932, 2002 | 89 | 2002 |
The two α-tubulin isotypes in budding yeast have opposing effects on microtubule dynamics in vitro CJ Bode, ML Gupta Jr, KA Suprenant, RH Himes EMBO reports 4 (1), 94-99, 2003 | 87 | 2003 |
Paclitaxel‐induced microtubule stabilization causes mitotic block and apoptotic‐like cell death in a paclitaxel‐sensitive strain of Saccharomyces cerevisiae TB Foland, WL Dentler, KA Suprenant, ML Gupta Jr, RH Himes Yeast 22 (12), 971-978, 2005 | 73 | 2005 |
Mutagenesis of β‐tubulin cysteine residues in Saccharomyces cerevisiae: Mutation of cysteine 354 results in cold‐stable microtubules ML Gupta Jr, CJ Bode, CA Dougherty, RT Marquez, RH Himes Cell motility and the cytoskeleton 49 (2), 67-77, 2001 | 69 | 2001 |
The kinesin-8 Kip3 scales anaphase spindle length by suppression of midzone microtubule polymerization RS Rizk, KA DiScipio, KG Proudfoot, ML Gupta Jr The Journal of cell biology 204 (6), 965-975, 2014 | 45 | 2014 |
Spatial control of microtubule length and lifetime by opposing stabilizing and destabilizing functions of Kinesin-8 Y Fukuda, A Luchniak, ER Murphy, ML Gupta Jr Current Biology 24 (16), 1826-35, 2014 | 33 | 2014 |
Synthesis and Biological Evaluation of a Biotinylated Paclitaxel with an Extra-Long Chain Spacer Arm LG Lis, MA Smart, A Luchniak, ML Gupta Jr, VJ Gurvich ACS medicinal chemistry letters 3 (9), 745-748, 2012 | 28 | 2012 |
Tubulin isotypes–functional insights from model organisms ET Nsamba, ML Gupta Jr Journal of Cell Science 135 (9), jcs259539, 2022 | 25 | 2022 |
Checkpoint Proteins Bub1 and Bub3 Delay Anaphase Onset in Response to Low Tension Independent of Microtubule-Kinetochore Detachment KG Proudfoot, SJ Anderson, S Dave, AR Bunning, PS Roy, A Bera, ... Cell Reports 27 (2), 416-428. e4, 2019 | 22 | 2019 |